Kalamazoo College , Biology
Graduate School
Wayne State University (1981)

Research Interest

  • Genome editing and transgenesis
  • Oncogene and nutrient collaboration in cancer
  • Ribosomopathies
  • Rodent models of cancer


Featured Publications LegendFeatured Publications

Hepatoblastoma modeling in mice places nrf2 within a cancer field established by mutant ?-catenin.
Comerford SA, Hinnant EA, Chen Y, Bansal H, Klapproth S, Rakheja D, Finegold MJ, Lopez-Terrada D, O?Donnell KA, Tomlinson GE, Hammer RE. J Clin Invest Insight. 2016 16 e88549.
Acetate dependence of tumors.
Comerford SA, Huang Z, Du X, Wang Y, Cai L, Witkiewicz A, Walters H, Tantawy MN, Fu A, Manning C, Horton JD, Hammer RE, McKnight SL, Tu BP Cell. 2014 159 1591-1602
Comparative analysis of SV40 17kT and LT function in vivo demonstrates that LT's C-terminus re-programs hepatic gene expression and is necessary for tumorigenesis in the liver.
Comerford SA, Schultz N, Hinnant EA, Klapproth S, Hammer RE Oncogenesis 2012 1 e28
Induction of hepatocyte proliferation and death by modulation of T-Antigen expression.
Comerford, S.A., Clouthier, D.E., Hinnant, E., and Hammer, R.E. Oncogene 2003 22 2515-2530

Honors & Awards

  • State Capital of Wiesbaden, Germany
    Carol-Nachman Prize in Rheumatology (1992)
  • USDA Unit Award for Distinguished Service
    Application of Gene Transfer to Farm Animals (1989)
  • University of Pennsylvania School of Veterinary Medicine
    NIH Postdoctoral Fellowship (1983)

Professional Associations/Affiliations

  • International Society for Stem Cell Research (ISSCR) (2018)
  • International Society of Transgenic Technology (ISTT) (2010)
  • Public Responsibility in Medicine and Research (PRIMR) (2016)
  • Society for Developmental Biology (2020)