Kalamazoo College , Biology
Graduate School
Wayne State University (1981)

Research Interest

  • In vivo models of cancer
  • Oncogene and growth factor collaboration in cancer
  • Regulation of growth and proliferation
  • Regulation of liver growth


Featured Publications LegendFeatured Publications

Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis
Engelking, L.J., Kuriyama, H, Hammer, R.E., Horton, J. D., Brown, M.S.,Goldstein, J. L. and Liang, G J. Clinical Investigation Spring 2004 113 1168-75
Overexpression of sterol regulatory element-binding protein 1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver
Horton, J. D., Shiomorura, I., Ikemoto, S.,Bashmakov, Y., and Hammer, R.E. J. Biological Chemistry 2003 278 36652-60
Induction of hepatocyte proliferation and death by modulation of T-Antigen expression.
Comerford, S.A., Clouthier, D.E., Hinnant, E., and Hammer, R.E. Oncogene 2003 22 2515-2530
Regulation of cytosolic phosphoenolpyruvate carboxykinase gene expression in adipocytes
Beale, E.G., Forest, C., and Hammer, R.E. Biochimie 2003 85 1207-11
Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta1 transgenic mice.
Clouthier, D.E., Comerford, S.A., and Hammer, R.E. J. Clin. Invest. 1997 100 2697-2713

Honors & Awards

  • Jackson Laboratory, Bar Harbor, ME
    Scientific Advisory Bard of Induced Mutant Resource (1996)
  • State Capital of Wiesbaden, Germany
    Carol-Nachman Prize in Rheumatology (1992)
  • USDA Unit Award for Distinguished Service
    Application of Gene Transfer to Farm Animals (1989)
  • University of Pennsylvania School of Veterinary Medicine
    NIH Postdoctoral Fellowship (1983)

Professional Associations/Affiliations

  • American Association for the Advancement of Science
  • American Society of Cell Biology
  • Society for Developmental Biology