Yanbin Zheng, Ph.D. Titles and Appointments Assistant Professor Schools Medical School Departments Pediatrics Biography Dr. Zheng served as a Postdoctoral Scholar in the Department of Medicine at the University of Chicago from 2003 to 2008. He then took the position as a Research Associate (Assistant Professor) in the Department of Pediatrics at the University of Chicago until 2011. He has since served as an Assistant Professor within the Department of Pediatrics at UT Southwestern. Education Undergraduate Henan Medical University - ? (1997) Graduate School Tianjin University (2000), Biomedical Engineering Graduate School Tsinghua University (2003), Biochemistry Research Interest Muscular Dystrophy Myogenic Differentiation Oncogenes and Tumor Suppressor Genes Rhabdomyosarcoma Publications Ectopic PLAG1 induces muscular dystrophy in the mouse Aguayo JS, Shelton JM, Tan W, Rakheja D, Cai C, Shalaby A, Lee J, Iannaccone ST, Xu L, Chen K, Burns DK, Zheng Y Biochemical and Biophysical Research Communications 2023 Jul 665 159-168 Exon skipping in genes encoding lineage-defining myogenic transcription factors in rhabdomyosarcoma Butler E, Xu L, Rakheja D, Schwettmann B, Toubbeh S, Guo L, Kim J, Skapek SX, Zheng Y Cold Spring Harbor Molecular Case Studies 2022 Aug 8 Bayesian modeling identifies PLAG1 as a key regulator of proliferation and survival in rhabdomyosarcoma cells Zheng Y, Xu L, Hassan M, Zhou X, Zhou Q, Rakheja D, Skapek SX Molecular Cancer Research 2020 18 364-374 Twist2 amplification in rhabdomyosarcoma represses myogenesis and promotes oncogenesis by redirecting MyoD DNA binding Li S, Chen K, Zhang Y, Barnes SD, Jaichander P, Zheng Y, Hassan M, Malladi VS, Skapek SX, Xu L, Bassel-Duby R, Olson EN, Liu N Genes and Development 2019 Jun 33 626-640 Identification of de novo enhancers activated by tgfβ to drive expression of CDKN2A and B in hela cells Liu YT, Xu L, Bennett L, Hooks JC, Liu J, Zhou Q, Liem P, Zheng Y, Skapek SX Molecular Cancer Research 2019 17 1854-1866 Novel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib Hassan M, Butler E, Wilson R, Roy A, Zheng Y, Liem P, Rakheja D, Pavlick D, Young LL, Rosenzweig M, Erlich R, Ali SM, Leavey PJ, Williams Parsons D, Skapek SX, Laetsch TW Cold Spring Harbor Molecular Case Studies 2019 5 Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes Xu L, Zheng Y, Liu J, Rakheja D, Singleterry S, Laetsch TW, Shern JF, Khan J, Triche TJ, Hawkins DS, Amatruda JF, Skapek SX Cell Reports 2018 Jul 24 238-251 Negative regulation of initial steps in skeletal myogenesis by mTOR and other kinases Wilson RA, Liu J, Xu L, Annis J, Helmig S, Moore G, Timmerman C, Grandori C, Zheng Y, Skapek SX Scientific reports 2016 Feb 6 Arf Induction by Tgfβ Is Influenced by Sp1 and C/ebpβ in Opposing Directions Zheng Y, Devitt C, Liu J, Iqbal N, Skapek SX PloS one 2013 Aug 8 A distant, cis-acting enhancer drives induction of Arf by Tgfβ in the developing eye Zheng Y, Devitt C, Liu J, Mei J, Skapek SX Developmental Biology 2013 Aug 380 49-57 Results 1-10 of 23 1 2 3 Next Last Honors & Awards Rally and Infinite Love Independent Investigator Grant Award (2023) Wipe Out Kids Cancer Research Grant Award (2022) Childrens Cancer Fund Research Grant Award (2021) Andrew McDonough B+ Foundation Childhood Cancer Research Grant Award (2018) Hyundai Hope Grant Award (2012)
