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Zhong-Jian Shen, M.D., Ph.D.

Zhong-Jian Shen, M.D., Ph.D.

Instructor

School
Medical School
Department
Pathology
  • Education
    Graduate School
    Kyungpook National University (1999), Biochemistry
  • Publications

    Star Featured Publications

    Featured
    Pin1 protein regulates Smad protein signaling and pulmonary fibrosis.
    Shen ZJ, Braun RK, Hu J, Xie Q, Chu H, Love RB, Stodola LA, Rosenthal LA, Szakaly RJ, Sorkness RL, Malter JS J. Biol. Chem. 2012 Jul 287 28 23294-305
    Featured
    The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.
    Shen ZJ, Esnault S, Schinzel A, Borner C, Malter JS Nat. Immunol. 2009 Mar 10 3
    Featured
    Thymic stromal lymphopoietin expression in allergic pulmonary inflammation is Pin1-dependent.
    Esnault S, Rosenthal LA, Shen ZJ, Westmark CJ, Sorkness RL, Malter JS J. Allergy Clin. Immunol. 2008 May 121 5
    Featured
    Pin1 regulates TGF-beta1 production by activated human and murine eosinophils and contributes to allergic lung fibrosis.
    Shen ZJ, Esnault S, Rosenthal LA, Szakaly RJ, Sorkness RL, Westmark PR, Sandor M, Malter JS J. Clin. Invest. 2008 Feb 118 2 479-90
    Featured
    Pinning down signaling in the immune system: the role of the peptidyl-prolyl isomerase Pin1 in immune cell function.
    Esnault S, Shen ZJ, Malter JS Crit. Rev. Immunol. 2008 28 1
    Featured
    A critical role for Pin1 in allergic pulmonary eosinophilia in rats.
    Esnault S, Rosenthal LA, Shen ZJ, Sedgwick JB, Szakaly RJ, Sorkness RL, Malter JS J. Allergy Clin. Immunol. 2007 Nov 120 5
    Featured
    Antisense targeting of TGF-beta1 augments BMP-induced upregulation of osteopontin, type I collagen and Cbfa1 in human Saos-2 cells.
    Shen ZJ, Kim SK, Jun DY, Park W, Kim YH, Malter JS, Moon BJ Exp. Cell Res. 2007 Apr 313 7
    Featured
    Pin1 modulates the type 1 immune response.
    Esnault S, Braun RK, Shen ZJ, Xiang Z, Heninger E, Love RB, Sandor M, Malter JS PLoS ONE 2007 2 2
    Featured
    The peptidyl-prolyl isomerase Pin1 regulates granulocyte-macrophage colony-stimulating factor mRNA stability in T lymphocytes.
    Esnault S, Shen ZJ, Whitesel E, Malter JS J. Immunol. 2006 Nov 177 10
    Featured
    The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils.
    Shen ZJ, Esnault S, Malter JS Nat. Immunol. 2005 Dec 6 12 1280-7