
Feiran Lu, Ph.D.
Assistant Professor
Department Molecular Genetics
Education
- Undergraduate
- Shandong University (2006), Biochemistry
- Graduate School
- Tsinghua University (2011), Structural Biology
Research Interest
- Cholesterol Metabolism
- Membrane Protein Structural Biology
Publications
Featured Publications
- Triazoles inhibit cholesterol export from lysosomes by binding to NPC1.
- Trinh MN, Lu F, Li X, Das A, Liang Q, De Brabander JK, Brown MS, Goldstein JL Proc. Natl. Acad. Sci. U.S.A. 2016 Dec
- Identification of NPC1 as the target of U18666A, an inhibitor of lysosomal cholesterol export and Ebola infection.
- Lu F, Liang Q, Abi-Mosleh L, Das A, De Brabander JK, Goldstein JL, Brown MS Elife 2015 Dec 4
- Structure and mechanism of the uracil transporter UraA.
- Lu F, Li S, Jiang Y, Jiang J, Fan H, Lu G, Deng D, Dang S, Zhang X, Wang J, Yan N Nature 2011 Apr 472 7342 243-6
- Structure of a fucose transporter in an outward-open conformation.
- Dang S, Sun L, Huang Y, Lu F, Liu Y, Gong H, Wang J, Yan N Nature 2010 Oct 467 7316 734-8
- Mechanism of substrate recognition and transport by an amino acid antiporter.
- Gao X, Zhou L, Jiao X, Lu F, Yan C, Zeng X, Wang J, Shi Y Nature 2010 Feb 463 7282 828-32
- Structure and mechanism of an amino acid antiporter.
- Gao X, Lu F, Zhou L, Dang S, Sun L, Li X, Wang J, Shi Y Science 2009 Jun 324 5934 1565-8
Professional Associations/Affiliations
- American Society for Biochemistry and Molecular Biology (2017)
- Sigma Xi (2017)