Ivan Pedrosa, M.D., Ph.D.

Ivan Pedrosa, M.D., Ph.D., is Professor of Radiology and Vice Chair of Radiology Research at UT Southwestern. He also holds the Jack Reynolds, M.D., Chair in Radiology, and is Co-Leader of the Kidney Cancer Program at the Simmons Comprehensive Cancer Center.

My passion about Radiology relies on the joy of continuously acquiring new knowledge in different areas of medicine, physics, and technology while maintaining a real appreciation about the privilege and responsibility of being part of a team of physicians who help that person behind the picture feel better.

Originally from Spain, Dr. Pedrosa earned his medical degree at the University Complutense in Madrid and completed his radiology residency training at the Hospital Clinico San Carlos in Madrid. He then received advanced training in trauma and emergency radiology through a fellowship at Jackson Memorial Hospital/Ryder Trauma Center in Miami, and in Body MRI through a fellowship at the Beth Israel Deaconess Medical Center in Boston.

Before joining the faculty at UT Southwestern in 2011, Dr. Pedrosa served as an Associate Professor of Radiology at Harvard Medical School and Director of Body MRI.

Research and clinical practice

As a body imager and clinical researcher, Dr. Pedrosa focuses on developing new MRI techniques to support translational research efforts in different diseases of the chest, abdomen, and pelvis. His primary areas of interest include kidney and prostate cancer; liver, pancreatic and biliary disease; and imaging of the gastrointestinal tract.

Dr. Pedrosa’s NIH-funded translational research program in kidney cancer focuses on implementing novel MRI techniques for identification of vascular MRI measures that correlate to aggressiveness and molecular measures of angiogenesis, and the measures of tumor perfusion as an indicator of initial and acquired resistance to antiangiogenic therapies in metastatic disease.

Investigating novel imaging techniques

Dr. Pedrosa has served as principal investigator and co-investigator in a number of clinical trials assessing novel imaging approaches. The overarching goal of his research is to translate novel imaging techniques into the clinical setting for more accurate diagnosis and robust evaluation of disease severity of different pathologies in the torso to improve patient outcomes. This is emphasized through the development and implementation of multiparametric MRI protocols that rely on robust and reproducible quantitative imaging strategies. These efforts provide the basis for data-driven optimization of clinical imaging protocols, including endorectal coil 3T prostate MRI, renal mass characterization, and diffuse liver disease.

Dr. Pedrosa is an active member of numerous national and international societies, including the Society of Computed Body Tomography/Magnetic Resonance Imaging (SCBT/MR), International Society of Magnetic Resonance Imaging in Medicine (ISMRM), Radiological Society if North America (RSNA), American College of Radiology, Sociedad Española de Radiología Medica, European Society of Radiology, American Urological Association and the American Society of Clinical Oncology. He currently serves as a scientific advisor for a recipient of the RSNA research scholar grant and has served in multiple society committees, including as a member of the ISMRM’s Annual Meeting Program Committee, Young Investigator Committee, and Educational Committee; and as chair of the SCBT/MR’s Scientific Committee. He is also a member of the American College of Radiology Imaging Network’s (ACRIN) Experimental Imaging Science Committee and the Renal Cancer Task Force of the Genitourinary Steering Committee of the National Cancer Institute.

It is not only a privilege to contribute to the Radiology education of our trainees at UT Southwestern, it is also a pleasure to see them become the leaders in our field.

Educating, editing and lecturing

In addition to authoring more than 130 peer-reviewed works and 35 additions and chapters to other texts, Dr. Pedrosa serves as a reviewer for multiple medical and scientific journals, including Radiology, American Journal of Roentgenology, Cancer, Radiographics, Journal of Urology, and Clinical Cancer Research. He has served as a visiting professor at universities and medical centers within the U.S. and abroad, and has also been invited to speak at more than 90 national and international conferences.

As a dedicated radiology educator and mentor, Dr. Pedrosa received the Teacher of the Year Award at Beth Israel Medical Center (2005) and the Golden Apple Award at UT Southwestern (2014). He has also served as senior mentor of many trainees who have received awards, including the Joseph E. and Nancy O. Whitley Award for the best manuscript on radiology education from the Association of University Radiologists (2006), the RSNA Trainee Research Prize (2012, 2015), and the Lauterbur Award for the best MRI abstract (2012, 2015) and Resoundant Innovation Award (2015) from the SCBT/MR.

Personal note

Dr. Pedrosa is passionate about cooking for his family and friends and watching movies, including classic movies from Hollywood’s Golden Age.

Fellowship

MD Anderson Cancer Center (1993), Research

Medical School

Universidad Complutense de Madrid, Spain (1994)

Residency

Hospital Universitario San Carlos (1995), Family Medicine

Residency

Hospital Universitario San Carlos (2000), Diagnostic Radiology

Fellowship

Jackson Memorial Hospital (2001), Trauma/emergency Radiology

Fellowship

Body MRI Fellowship Prog. -Beth Israel Deaconess Hospital (2002), Body Imaging

Graduate School

Universidad de Oviedo (2017)

Other Post Graduate Training

Universiddad de Oviedo (2017)

• Kidney Cancer
• Novel MRI techniques for physiologic assessment of abdominal/pelvic disease
• Pancreas and Biliary Disease

Featured Publications

HIF2 inactivation and tumor suppression with a tumor-directed RNA-silencing drug in mice and humans.

Ma Y, Joyce A, Brandenburg O, Saatchi F, Stevens C, Tcheuyap VT, Christie A, Do Q, Fatunde O, Macchiaroli A, Wong SC, Woolford L, Yousuf Q, Miyata J, Carrillo D, Onabolu O, McKenzie T, Mishra A, Hardy T, He W, Li D, Ivanishev A, Zhang Q, Pedrosa I, Kapur P, Schluep T, Kanner SB, Hamilton J, Brugarolas J, Clin Cancer Res 2022 Oct

Multicenter Evaluation of Multiparametric MRI Clear Cell Likelihood Scores in Solid Indeterminate Small Renal Masses.

Schieda N, Davenport MS, Silverman SG, Bagga B, Barkmeier D, Blank Z, Curci NE, Doshi AM, Downey RT, Edney E, Granader E, Gujrathi I, Hibbert RM, Hindman N, Walsh C, Ramsay T, Shinagare AB, Pedrosa I, Radiology 2022 Mar 211680

Stereotactic ablative radiation therapy for renal cell carcinoma with inferior vena cava tumor thrombus.

Freifeld Y, Pedrosa I, Mclaughlin M, Correa RM, Louie AV, Maldonado JA, Tang C, Kadow B, Kutikov A, Uzzo RG, Porta C, Bucknell NW, Siva S, Brugarolas J, Margulis V, Timmerman R, Hannan R, Urol Oncol 2022 Feb

Deep learning kidney segmentation with very limited training data using a cascaded convolution neural network.

Guo J, Odu A, Pedrosa I, PLoS One 2022 17 5 e0267753

Determinants of renal cell carcinoma invasion and metastatic competence.

Kim K, Zhou Q, Christie A, Stevens C, Ma Y, Onabolu O, Chintalapati S, Mckenzie T, Tcheuyap VT, Woolford L, Zhang H, Singla N, Parida PK, Marquez-Palencia M, Pedrosa I, Margulis V, Sagalowsky A, Xie Z, Wang T, Durinck S, Modrusan Z, Seshagiri S, Kapur P, Brugarolas J, Malladi S, Nat Commun 2021 10 12 1 5760

Outcome and Immune Correlates of a Phase II Trial of High-Dose Interleukin-2 and Stereotactic Ablative Radiotherapy for Metastatic Renal Cell Carcinoma.

Hannan R, Mohamad O, Diaz de Leon A, Manna S, Pop LM, Zhang Z, Mannala S, Christie A, Christley S, Monson N, Ishihara D, Hsu EJ, Ahn C, Kapur P, Chen M, Arriaga Y, Courtney K, Cantarel B, Wakeland EK, Fu YX, Pedrosa I, Cowell L, Wang T, Margulis V, Choy H, Timmerman RD, Brugarolas J, Clin Cancer Res 2021 Sep

Germline and sporadic mTOR pathway mutations in low-grade oncocytic tumor of the kidney.

Kapur P, Gao M, Zhong H, Chintalapati S, Mitui M, Barnes SD, Zhou Q, Miyata J, Carrillo D, Malladi VS, Rakheja D, Pedrosa I, Xu L, Kinch L, Brugarolas J, Mod Pathol 2021 Sep

Towards an inclusive digital literacy: An experimental intervention study in a rural area of Brazil.

Nogueira VB, Teixeira DG, de Lima IACN, Moreira MVC, de Oliveira BSC, Pedrosa IMB, de Queiroz JW, Jeronimo SMB, Educ Inf Technol (Dordr) 2021 Sep 1-28

Single-shot RARE with Dixon: Application to robust abdominal imaging with uniform fat and water separation at 3T.

Wang X, Udayakumar D, Xi Y, Rofsky NM, Pedrosa I, Madhuranthakam AJ, Magn Reson Med 2021 09 86 3 1463-1471

Neoadjuvant SABR for Renal Cell Carcinoma Inferior Vena Cava Tumor Thrombus-Safety Lead-in Results of a Phase 2 Trial.

Margulis V, Freifeld Y, Pop LM, Manna S, Kapur P, Pedrosa I, Christie A, Mohamad O, Mannala S, Singla N, Wait M, Bagrodia A, Woldu SL, Gahan J, Brugarolas J, Timmerman R, Hannan R, Int J Radiat Oncol Biol Phys 2021 Jul 110 4 1135-1142

• Cum Laude Award (PhD Thesis)
  University of Oviedo, Asturias, Spain (2017)
• Certificate of Merit (Senior Mentor)
  Radiological Society of North America (2016)
• Certificate of Merit (Senior Mentor)
  Radiological Society of North America (2015)
• Lauterbur Award for Best Scientific Abstract (Senior Mentor)
  Society of Computed Body Tomography/Magnetic Resonance Imaging (2015)
• Resident Trainee Research Prize (Senior Mentor)
  Radiological Society of North America (2015)
• Resoundant Innovation Award (Senior Mentor)
  Society of Computed Body Tomography/Magnetic Resonance Imaging (2015)
• Editor's Recognition Award with Special Distinction
  Radiology (2014)
• Gold Apple Award
  UT Southwestern Medical Center (2014)
• Fellow
  Society of Computed Body Tomography/Magnetic Resonance Imaging (2011)
• Editor's Recognition Award with Distinction in Reviewing
  Radiology (2009)
• Editor's Recognition Award with Special Distinction
  Radiology (2008)
• Joseph E. and Nancy O. Whitley Award (Senior Mentor)
  Association of University Radiologists (2006)
• Norman Joffe, MD Award
  Beth Israel Deaconess Medical Center (2006)
• Teacher of the Year Award
  Beth Israel Deaconess Medical Center (2005)

• American College of Radiology
• Dallas County Medical Society/Texas Medical Association
• European Society of Radiology
• International Society of Magnetic Resonance in Medicine (ISMRM)
• New England Roentgen Ray Society
• Radiological Society of North America (RSNA)
• Sociedad Española de Radiología Medica (SERAM)
• Society of Computed Body Tomography/Magnetic Resonance Imaging (SCBT/MR)
• Texas Radiological Society