Biography

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Sean J. Morrison is the director of the Children’s Medical Center Research Institute (CRI) at UT Southwestern and a Howard Hughes Medical Institute investigator. He holds the Mary McDermott Cook Chair in Pediatric Genetics and the Kathryne and Gene Bishop Distinguished Chair in Pediatric Research. Dr. Morrison completed a B.Sc. in biology and chemistry at Dalhousie University (1991), a Ph.D. in immunology at Stanford University (1996), and a postdoctoral fellowship in neurobiology at Caltech (1999). From 1999 to 2011, Dr. Morrison was a professor at the University of Michigan, where he directed their Center for Stem Cell Biology.

Among other awards, Dr. Morrison received the Presidential Early Career Award for Scientists and Engineers (2003), a MERIT Award from the National Institute on Aging (2009), and was elected to the National Academy of Medicine (2018). Dr. Morrison served as the President of the International Society for Stem Cell Research (2015-2016) and has been active in public policy issues surrounding stem cell research, testifying before the U.S. Congress, and serving as a leader in the successful “Proposal 2” campaign to protect and regulate stem cell research in Michigan’s state constitution.

The Morrison laboratory studies the mechanisms that maintain stem cell function in adult tissues and the ways in which cancer cells hijack these mechanisms to enable neoplastic proliferation. A better understanding of these mechanisms offers the potential to yield new regenerative medicine and cancer therapies.

Morrison Laboratory

Education

Undergraduate
Dalhousie University - Canada (1991), Biology
Graduate School
Stanford University (1996)

Research Interest

  • Cancer stem cell biology
  • Melanoma cell proliferation and metastasis
  • Stem cell aging
  • Stem cell self-renewal

Publications

Featured Publications LegendFeatured Publications

Honors & Awards

  • National Academy of Medicine
    (2018)
  • CPRIT Scholar in Cancer Research
    (2016)
  • MERIT Award, National Institute on Aging
    (2009)
  • Harland Winfield Mossman Award, American Association of Anatomists
    (2008)
  • McCulloch and Till Award, International Society for Hematology & Stem Cells
    (2007)
  • Presidential Early Career Award for Scientists and Engineers, White House Office of Science and Technology
    (2003)

Professional Associations/Affiliations

  • President, International Society for Stem Cell Research (2015-2016)
  • Senior Editor, eLife (2014)
  • Investigator, Howard Hughes Medical Institute (2000)