Venkatakrishna Kakkilaya, M.D., is an Associate Professor in the Department of Pediatrics at UT Southwestern Medical Center. Board certified in both pediatrics and neonatology, Dr. Kakkilaya joined the UT Southwestern faculty in 2011.

Dr. Kakkilaya earned his medical degree at Karnatak University, followed by residencies in pediatrics at VM Medical College in India and later at LSU Health Sciences Center Shreveport. He subsequently completed a fellowship in neonatal-perinatal medicine at LSU Health Sciences Center Shreveport. He is credentialed to practice at Children’s Health.

Dr.Kakkilaya's research interest are focused on non invasive respiratory support of preterm infants and quality improvement in NICU. 


Medical School
Karnatak University (1990)
VM Medical College, India (1993), Pediatrics
LSU Health Sciences Center Shreveport (2007), Pediatrics
LSU Health Sciences Center Shreveport (2010), Neonatal-perinatal Medicine

Research Interest

  • Less invasive surfactant administration
  • Nasal CPAP: Optimal delivery systems and weaning strategies in extremely low birth weight infants
  • Neonatal abstinence syndrome
  • New tools in improving informed decision making in the NICU
  • Non invasive respiratory support in preterm infants


Featured Publications LegendFeatured Publications

Evaluation of a respiratory care protocol including less invasive surfactant administration in preterm infants.
Chan CS, Chiu M, Ariyapadi S, Brown LS, Burchfield P, Simcik V, Garcia K, Mazioniene K, Jaleel MA, Wyckoff MH, Kapadia VS, Kakkilaya V, Pediatr Res 2023 Dec
Risk Factors for Admission Hyperthermia and Associated Outcomes in Preterm Infants.
Chiu M, Mir I, Adhikari E, Heyne R, Ornelas N, Tolentino-Plata K, Thomas A, Burchfield P, Simcik V, Ramon E, Brown LS, Nelson DB, Wyckoff MH, Kakkilaya V, J Pediatr 2023 Nov 113842
RDS-NExT workshop: consensus statements for the use of surfactant in preterm neonates with RDS
Should less invasive surfactant administration (LISA) become routine practice in US neonatal units?
Kakkilaya V, Gautham KS, Pediatr Res 2022 Aug
Decreasing delivery room CPAP-associated pneumothorax at =35-week gestational age.
Stocks EF, Jaleel M, Smithhart W, Burchfield PJ, Thomas A, Mangona KLM, Kapadia V, Wyckoff M, Kakkilaya V, Brenan S, Brown LS, Clark C, Nelson DB, Brion LP, J Perinatol 2022 Feb
Decreasing Continuous Positive Airway Pressure Failure in Preterm Infants.
Kakkilaya VB, Weydig HM, Smithhart WE, Renfro SD, Garcia KM, Brown CM, He H, Wagner SA, Metoyer GC, Brown LS, Kapadia VS, Savani RC, Jaleel MA, Pediatrics 2021 Sep
Noninvasive Ventilation in the Delivery Room for the Preterm Infant.
Weydig H, Ali N, Kakkilaya V, Neoreviews 2019 09 20 9 e489-e499
Delivery Room Continuous Positive Airway Pressure and Pneumothorax.
Smithhart W, Wyckoff MH, Kapadia V, Jaleel M, Kakkilaya V, Brown LS, Nelson DB, Brion LP, Pediatrics 2019 Aug
Early predictors of continuous positive airway pressure failure in preterm neonates.
Kakkilaya V, Wagner S, Mangona KLM, Steven Brown L, Jubran I, He H, Savani RC, Kapadia VS, J Perinatol 2019 May
The use of less invasive surfactant administration (LISA) in the United States with review of the literature.
Kurepa D, Perveen S, Lipener Y, Kakkilaya V J Perinatol 2019 Mar 39 3 426-432

Honors & Awards

  • John Haven Emerson Award
  • Young Investigator Award Finalist, Southern Society of Pediatric Research

Professional Associations/Affiliations

  • AAP, Section on Perinatal Medicine (2010)
  • Fellow American Academy of Pediatrics (2007)
  • Member of Royal College of Physicians (1997)
  • Society of Pediatric Research (2022)
  • Southern Society of Pediatric Research (2010)