Kemp Kernstine, M.D., Ph.D.
Department Cardiovascular & Thoracic Surgery
Kemp Kernstine, M.D., Ph.D., trained to become the subspecialty surgeon he is today for 13 years. Now, as the only general thoracic surgeon associated with an academic medical center in North Texas, the expertise he offers is crucial for patients with conditions involving the lungs, esophagus, mediastinum, or chest wall.
Dr. Kernstine is Professor and Chief of the Division of Thoracic Surgery at UT Southwestern Medical Center and holds the Robert Tucker Hayes Foundation Distinguished Chair in Cardiothoracic Surgery. He completed his undergraduate and medical studies at Duke University. His internship and general surgery residency training were at the University of Minnesota in Minneapolis where he completed his Ph.D. as well. He pursued further training in heart and lung surgery at The Brigham and Women’s Hospital, Harvard Medical School, as a general thoracic track resident.
Board certified in surgery and thoracic surgery, Dr. Kernstine has numerous professional affiliations that include the American Medical Association, the American College of Surgeons, the American College of Chest Physicians, the American Thoracic Society, the American Association of Thoracic Surgeons, the Society of Thoracic Surgeons, the Society of Surgical Oncologists, the Western Thoracic Society, and the International Society of Minimally Invasive Cardiothoracic Surgeons. He has served in numerous leadership roles of many of these societies.
In addition to his clinical work, which involves the surgical management of a wide spectrum of benign and malignant diseases of the chest often treated with robotic surgery, Dr. Kernstine has strong research interests in minimally invasive and robotic surgery procedures, the surgical evaluation, and treatment of lung and esophageal cancer, mesothelioma, and thymic cancers. He has also studied the treatment of benign esophageal disease such as esophageal masses, achalasia, hiatal hernia, and gastro-esophageal reflux disease and is interested in the study of thymectomy in the treatment of myasthenia gravis.
Dr. Kernstine has received funding from the National Cancer Institute and various regional and national grants and has published numerous articles, abstracts and books on lung and esophageal cancer and chest surgery. He is both nationally and internationally recognized for his work.
- Medical School
- Duke University School of Medicine (1982)
- University of Minnesota Medical School (1985), General Surgery
- University of Minnesota Medical School (1988), Research
- University of Minnesota Medical School (1990), Surgery
- Brigham and Women's Hospital (1993), Cardiothoracic Surgery
- Brigham and Women's Hospital (1994), Cardiothoracic Surgery
- V A Medical Center - West Roxbury (1995), Cardiothoracic Surgery
- Graduate School
- University of Minnesota, Minneapolis (1996)
- Other Post Graduate Training
- University of Minnesota, Minneapolis (1996)
- Lung Cancer and Esophageal Cancer
- Minimally Invasive and Robotic Surgical Approaches
- Molecular Early Diagnosis, Staging and Evaluation of Thoracic Malignancies
- Serological antibodies against LY6K as a diagnostic biomarker in esophageal squamous cell carcinoma.
- Zhang B, Zhang Z, Zhang X, Gao X, Kernstine KH, Zhong L Biomarkers 2012 Jun 17 4 372-8
- A case of diffuse large B-cell lymphoma in association with paraesophageal leiomyoma: highlighting false-positivity of PET scan and importance of tissue diagnosis.
- Grover RS, Kernstine K, Krishnan A J Natl Compr Canc Netw 2012 May 10 5 577-81
- Putative multifunctional signature of lung metastases in dedifferentiated chondrosarcoma.
- Malchenko S, Seftor EA, Nikolsky Y, Hasegawa SL, Kuo S, Stevens JW, Poyarkov S, Nikolskaya T, Kucaba T, Wang M, Abdulkawy H, Casavant T, Morcuende J, Buckwalter J, Hohl R, Deyoung B, Kernstine K, Bonaldo Mde F, Hendrix MJ, Soares MB, Soares VM Sarcoma 2012 2012 820254
- Fen1 mutations that specifically disrupt its interaction with PCNA cause aneuploidy-associated cancer.
- Zheng L, Dai H, Hegde ML, Zhou M, Guo Z, Wu X, Wu J, Su L, Zhong X, Mitra S, Huang Q, Kernstine KH, Pfeifer GP, Shen B Cell Res. 2011 Jul 21 7 1052-67
- Autoantibodies against MMP-7 as a novel diagnostic biomarker in esophageal squamous cell carcinoma.
- Zhou JH, Zhang B, Kernstine KH, Zhong L World J. Gastroenterol. 2011 Mar 17 10 1373-8
- Minimally invasive and robotic-assisted thymus resection.
- Limmer KK, Kernstine KH Thorac Surg Clin 2011 Feb 21 1 69-83, vii
- Autoantibodies against MMP-7 as a novel diagnostic biomarker in esophageal squamous cell carcinoma
- Zhou JH, Zhang B, Kernstine KH, Zhong L. World J Gastroenterol 2011 2011 17 (10) 1373-8
- A practical guide of the southwest oncology group to measure malignant pleural mesothelioma tumors by RECIST and modified RECIST criteria.
- Tsao AS, Garland L, Redman M, Kernstine K, Gandara D, Marom EM. Journal of Thoracic Oncology 2011 2011 6 (3) 598-601
- Predictors of finding benefit after lung cancer diagnosis.
- Thornton AA, Owen JE, Kernstine K, Koczywas M, Grannis F, Cristea M, Reckamp K, Stanton AL. Psycho-Oncology 2011 2011
- Protein microarray: Sensitive and effective immunodetection for drug residues.
- Zhong L, Zhang W, Zer C, Ge K, Gao X, Kernstine KH BMC Biotechnology 2010 10 12-18
Honors & Awards
- Castle Connolly Americas Top Doctors
2008 - 2012 (2012)
- Castle Connolly Americas Top Doctors for Cancer
2005 - 2012 (2012)
- Brigham and Women's Hospital Thoracic Alumnus of the Year
- Willem J. Kolff Young Investigators Award
American Society for Artificially Implantable Organs (1988)
- Howard Hughes Medical Research Fellow
Duke University (1980)
- American Association of Thoracic Surgery
- American College of Surgeons, Fellow
- International Association for the Study of Lung Cancer
- International Society of Minimally Invasive Cardiothoracic Surgery
- Society of Thoracic Surgeons