Shunxing Rong, Ph.D. Assistant Professor School Medical School Department Center for Human Nutrition | Internal Medicine Biography Shunxing Rong obtained his Bachelor and master degrees from Fudan University, School of Public Health (former Shanghai Medical University) in 2002 and 2005, respectively. He received his Ph.D from Wake Forest University School of Medicine in 2010. Dr. Rong did his postdoctoral training in Dr. Jay Horton laboratory at UT Southwestern Medical Center (2011-2017). After that Dr. Rong was appointed as an assistant professor in the Center for Human Nutrition and Department of Molecular Genetics. Education Undergraduate Fudan University (2002), Medicine Graduate School Fudan University (2005), Public Health Graduate School Wake Forest Univ - Undergradua (2010), Pathology Research Interest Cholesterol and fatty acid homeostasis Obesity and diabetes Publications Featured Publications DGAT2 inhibition blocks SREBP-1 cleavage and improves hepatic steatosis by increasing phosphatidylethanolamine in the ER. Rong S, Xia M, Vale G, Wang S, Kim CW, Li S, McDonald JG, Radhakrishnan A, Horton JD, Cell Metab 2024 Feb Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity. Zhang Z, Xun Y, Rong S, Yan L, SoRelle JA, Li X, Tang M, Keller K, Ludwig S, Moresco EMY, Beutler B, Nat Commun 2022 Jul 13 1 4136 Osteocalcin and Non-Alcoholic Fatty Liver Disease: Lessons From Two Population-Based Cohorts and Animal Models. Xia M, Rong S, Zhu X, Yan H, Chang X, Sun X, Zeng H, Li X, Zhang L, Chen L, Wu L, Ma H, Hu Y, He W, Gao J, Pan B, Hu X, Lin H, Bian H, Gao X, J Bone Miner Res 2021 Apr 36 4 712-728 Hepatic deletion of Mboat7 (LPIAT1) causes activation of SREBP-1c and fatty liver. Xia M, Chandrasekaran P, Rong S, Fu X, Mitsche MA, J Lipid Res 2021 Feb 62 100031 Cholesterol auxotrophy and intolerance to ezetimibe in mice with SREBP-2 deficiency in the intestine. Rong S, McDonald J, Engelking L J. Lipid Res. 2017 Jun Expression of SREBP-1c requires SREBP-2-mediated generation of a sterol ligand for LXR in livers of mice. Rong S, Cortés VA, Rashid S, Anderson NN, McDonald JG, Liang G, Moon YA, Hammer RE, Horton JD Elife 2017 Feb 6 CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL. Bartuzi P, Billadeau DD, Favier R, Rong S, Dekker D, Fedoseienko A, Fieten H, Wijers M, Levels JH, Huijkman N, Kloosterhuis N, van der Molen H, Brufau G, Groen AK, Elliott AM, Kuivenhoven JA, Plecko B, Grangl G, McGaughran J, Horton JD, Burstein E, Hofker MH, van de Sluis B Nat Commun 2016 Mar 7 10961 Histone deacetylase 9 represses cholesterol efflux and alternatively activated macrophages in atherosclerosis development. Cao Q, Rong S, Repa JJ, St Clair R, Parks JS, Mishra N Arterioscler. Thromb. Vasc. Biol. 2014 Sep 34 9 1871-9 Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2-/- lipodystrophic mice independent of hepatocyte leptin receptors. Cortés VA, Cautivo KM, Rong S, Garg A, Horton JD, Agarwal AK J. Lipid Res. 2014 Feb 55 2 276-88 Omega-3 fatty acids ameliorate atherosclerosis by favorably altering monocyte subsets and limiting monocyte recruitment to aortic lesions. Brown AL, Zhu X, Rong S, Shewale S, Seo J, Boudyguina E, Gebre AK, Alexander-Miller MA, Parks JS Arterioscler. Thromb. Vasc. Biol. 2012 Sep 32 9 2122-30 Results 1-10 of 14 1 2 Next Last
