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James Forman, D.M.D, Ph.D.

James Forman, D.M.D, Ph.D.

Professor Emeritus

School
Medical School
Department
Immunology
Graduate Programs
Immunology, Molecular Microbiology
  • Education
    Graduate School
    Tufts University
    Graduate School
    Tufts University (1965)
    Graduate School
    Tufts University (1971)
  • Research Interest
    • CD8 T cells
    • class I antigens
    • Innate immunity
    • NK cells
  • Publications

    Star Featured Publications

    Featured
    Memory CD8+ T Cells Provide Innate Immune Protection against Listeria monocytogenes
    Berg, R., Crossley, E., Murray, S. and Forman, J. J. Experimental Medicine 2003 198 1583
    Featured
    MHC Class Ib Restricted CTL Provide Protection Against Primary and Secondary Listeria monocytogenes Infection.
    Seaman, M., Wang, C.-R., and J. Forman. J. Immunology 2000 165 5192-5201
    Featured
    The pathway for processing leader-derived peptides that regulate the maturation and expression of Qa-1b.
    Bai, A., Broen, J and Forman, J. Immunity 1998 9 413-421
    Featured
    The effect of the proteasome inhibitor lactacystin on the presentation of Tap-dependent and -independent peptide epitopes by class I molecules.
    Bai, A. and Forman, J. J. Immunol. 1997 159 2139-46
    Featured
    Identification of a Tap-dependent leader peptide recognized by alloreactive T cells specific for a class IB antigen.
    Aldrich, C.J., DeCloux, A., Woods, A.S., Cotter, R.J., Soloski, M., and Forman, J. Cell 1994 79 649-658
    Featured
    Negative and positive selection of antigen-specific cytotoxic T lymhoyctes affected by the 3 domain of MHC I molecules.
    Aldrich, C.J., Hammer, R.E., Koszinowski, U., Hood, L., Stroynowski, I., and Forman, J. Nature 1991 352 718-721
    Imatinib mesylate inhibits antigen-specific memory CD8 T cell responses in vivo.
    Parisa Sinai, Rance E. Berg, J. Marshall Haynie, Merrill J. Egorin, Robert L. Ilaria Jr, and James Forman J. Immunology February 2007 178 2028-2037
    Thymus-dependent memory phenotype CD8 T cells in naive B6.H-2Kb-/-Db-/- animals mediate an antigen-specific response against Listeria monocytogenes.
    Su, Jie, Berg, R.E., Murray, S., and Forman, J J. Immunology Fall 2005 in press
    The role of TCR stimulation and TGF-beta in controlling the expression of CD94/NKG2A receptors on CD8 T cells.
    Gunturi, A, Berg, R.E., Crossley, E., Murray, S. and Forman J. European J. Immunology 2005 35 766-775
    CD4-CD8- T cells control intracellular bacterial infections both in vitro and in vivo.
    Cowley SC, Hamilton E, Frelinger JA, Su J, Forman J, Elkins KL. J. Experimental Medicine 2005 202 309-319