Dr. Lopez did her residency in Pediatrics at the University of Illinois at Chicago, IL,  and her fellowship in Pediatric Endocrinology at Massachusetts General Hospital/Harvard Medical School,  Boston, MA.

She has performed research in the area of type 2 diabetes and obesity in adults and pediatrics  and has participated in several multicenter clinical trials with new drugs for type 2 diabetes.

She is currently the Medical Director for the GENder, Education and Care Interdisciplinary Support (GENECIS) program, which provides mental health and endocrine care for gender non-conforming children and adolescents. Dr. Lopez is also currently co-chair of the Transgender Health Special Interest Group of the Pediatric Endocrine Society.


Medical School
Universidad La Salle/Facuitad de Medicina (2000)
University of Illinois at Chicago (2005), Pediatrics
Massachusetts General Hospital (2008), Pediatric Endocrinology

Research Interest

  • Gender dysphoria in children and adolescents
  • Metabolic effects of endocrine therapy in adolescents with gender dysphoria
  • Neurobiology of transgender children and adolescents


Featured Publications LegendFeatured Publications

An infant with hypercalcemia and rachitic changes: question.
Siddique K, Lucke A, Lucio D, Lopez X, Seikaly M Pediatr. Nephrol. 2013 Feb 28 2 245-6, 247-9
Insulin augmentation of glucose-stimulated insulin secretion is impaired in insulin-resistant humans.
Halperin F, Lopez X, Manning R, Kahn CR, Kulkarni RN, Goldfine AB Diabetes 2012 Feb 61 2 301-9
Exogenous insulin enhances glucose-stimulated insulin response in healthy humans independent of changes in free fatty acids.
Lopez X, Cypess A, Manning R, O'Shea S, Kulkarni RN, Goldfine AB J. Clin. Endocrinol. Metab. 2011 Dec 96 12 3811-21
Impact of GLP-1 and GLP-1 receptor agonists on cardiovascular risk factors in type 2 diabetes.
Verge D, López X Curr Diabetes Rev 2010 Jul 6 4 191-200
Insulin enhances glucose-stimulated insulin secretion in healthy humans.
Bouche C, Lopez X, Fleischman A, Cypess AM, O'Shea S, Stefanovski D, Bergman RN, Rogatsky E, Stein DT, Kahn CR, Kulkarni RN, Goldfine AB Proc. Natl. Acad. Sci. U.S.A. 2010 Mar 107 10 4770-5
Family history of diabetes impacts on interactions between minimal model estimates of insulin sensitivity and glucose effectiveness.
Lopez X, Bouché C, Tatro E, Goldfine AB Diabetes Obes Metab 2009 Feb 11 2 123-30
Human insulin analog--induced lipoatrophy.
Lopez X, Castells M, Ricker A, Velazquez EF, Mun E, Goldfine AB Diabetes Care 2008 Mar 31 3 442-4


Featured Books Legend Featured Books

Honors & Awards

  • Best grades of graduating class from Medical School
    Universidad La Salle Medical School, Mexico City (2000)
  • Graduation from Medical School with Honors
    Universidad La Salle Medical School, Mexico City (2000)

Professional Associations/Affiliations

  • American Academy of Pediatrics, Endocrinology Executive Committee Member (2016-2019)
  • Pediatric Endocrine Society, Co-chair of the Transgender and Gender Non-Conforming Youth SIG (2015)
  • World Professional Association for Transgender Health (WPATH) (2014)
  • Diabetes National Medical Advisor, Novo Nordisk, Spain (2008-2010)