Denise Marciano, M.D., Ph.D., is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center, and a member of its Division of Nephrology. She specializes in kidney disease.

Originally from Washington, D.C., Dr. Marciano holds a bachelor's degree in chemistry from Dartmouth College in Hanover, New Hampshire, where she graduated magna cum laude. She earned her doctorate in cellular biophysics from The Rockefeller University, and her medical degree from Weill Cornell University Medical College in New York. She completed internal medicine residency training, as well as fellowship training in nephrology, at the University of California San Francisco, where she also completed a postdoctoral research fellowship in the Louis F. Reichardt Lab.

Certified by the American Board of Internal Medicine in internal medicine and nephrology, she joined the UT Southwestern faculty in 2011.

Dr. Marciano focuses her research on understanding the cellular and molecular mechanisms that drive kidney development and regeneration. She uses a variety of cellular, genetic, and biochemical approaches to study these processes in renal tubules and the filtration units of the kidney, called glomeruli. She also studies the pathogenesis of human congenital kidney abnomalities and glomerular diseases. She has received several grant awards to support her research laboratory, including awards from the March of Dimes and the NIH. More details on her research program can be found at the Marciano Research Lab.



Graduate School
Rockefeller University (1999)
Other Post Graduate Training
Rockefeller University (1999)
Medical School
Cornell University Medical College (2001)
University of California, San Francisco (2004), Internal Medicine
University of California at San Francisco (2007), Nephrology

Research Interest

  • Cell Polarity
  • Glomerular Development, Structure, and Disease
  • Human Congenital Kidney Diseases
  • Kidney Development and Disease
  • Tubule Formation


Featured Publications LegendFeatured Publications

Honors & Awards

  • Elected Member, American Society for Clinical Investigation
    Physician-Scientist Honorary Society (2020)
  • Carolyn R. Bacon Distinguished Professorship in Medical Science and Education
    UT Southwestern (2019)
  • Fellow
    American Society of Nephrology (2017)
  • Basil O'Connor Scholar
    March of Dimes (2013)
  • Norman S. Coplon Extramural Grant
    Weil Cornell Medicine (2013)
  • K08 and NKF Young Investigator Awards
    National Kidney Foundation (2008)
  • National Research Service Award
    National Institutes of Health (2005)
  • Janet M. Glasgow Memorial Achievement Award
    Weill Cornell University Medical College (2001)

Professional Associations/Affiliations

  • American Heart Association
  • American Society of Nephrology
  • National Kidney Foundation