Biography

Denise Marciano earned her bachelor’s degree from Dartmouth College. She received her Ph.D. in Cellular Biophysics at the Rockefeller University and her M.D. at Cornell University. She completed the rest of her medical training at the University of California San Francisco, where she became drawn to caring for patients with kidney disease. At that time, she also developed a passion for research on how the kidney develops and functions. Lured by the opportunity to meld her clinical and scientific interests, she joined the faculty in Internal Medicine at UT Southwestern in 2011. She is also an attending physician at Parkland Memorial Hospital, where she sees patients with renal disease. Dr. Marciano’s interests outside of medicine and research include spending time with her family, hiking, and cooking.

The goal of Dr. Marciano’s research is to understand the cellular and molecular mechanisms that drive kidney development and repair after injury. She uses a variety of cellular, genetic, and biochemical approaches to study these processes in renal tubules and the filtration units of the kidney, called glomeruli. She has received several grant awards to support her research laboratory, including awards from the March of Dimes and the NIH. More details on her research program can be found at the Marciano Research Lab.

Education

Graduate School
Rockefeller University (1999)
Medical School
Cornell University Medical College (2001)
Residency
University of California, San Francisco (2004), Internal Medicine
Fellowship
University of California at San Francisco (2007), Nephrology

Research Interest

  • Cell polarity
  • Glomerular structure and function
  • Kidney development and disease
  • Tubulogenesis

Publications

Featured Publications LegendFeatured Publications

Uromodulin regulates renal magnesium homeostasis through the ion channel transient receptor potential melastatin 6 (TRPM6).
Nie M, Bal MS, Liu J, Yang Z, Rivera C, Wu XR, Hoenderop JGJ, Bindels RJM, Marciano DK, Wolf MTF J. Biol. Chem. 2018 Aug

Honors & Awards

  • Fellow of the American Society of Nephrology
    (2017)
  • March of Dimes Basil O'Connor Scholar
    (2013)
  • Norman S. Coplon Extramural Grant
    (2013)
  • K08 and NKF Young Investigator Awards
    (2008)
  • NRSA F32 grant
    (2005)
  • Janet M. Glasgow Memorial Achievement Award
    Graduated in top ten students at Cornell Univ Medical College (2001)
  • Magna cum laude and Phi Beta Kappa, Dartmouth College
    (1993)

Professional Associations/Affiliations

  • American Heart Association (2014)
  • American Society of Nephrology
  • National Kidney Foundation