
J Falck, Ph.D.
Professor
Endowed Title Robert A. Welch Distinguished Chair in Chemistry
Department Biochemistry | Pharmacology
Education
- Undergraduate
- Colorado State University (1970)
- Graduate School
- Colorado State University (1973)
Research Interest
- medicinal chemistry
- natural products isolation and identification
- organometalics
- synthetic methodology
- total synthesis
Publications
Featured Publications
- Picolinate Directed Arene meta-C-H Amination via FeCl3 Catalysis.
- Anugu RR, Munnuri S, Falck JR, J. Am. Chem. Soc. 2020 Feb
- Development of Robust 17(R),18(S)-Epoxyeicosatetraenoic Acid (17,18-EEQ) Analogues as Potential Clinical Antiarrhythmic Agents.
- Adebesin AM, Wesser T, Vijaykumar J, Konkel A, Paudyal MP, Lossie J, Zhu C, Westphal C, Puli N, Fischer R, Schunck WH, Falck JR, J. Med. Chem. 2019 Nov 62 22 10124-10143
- Cu(II)-Mediated N-H and N-Alkyl Aryl Amination and Olefin Aziridination.
- Munnuri S, Anugu RR, Falck JR, Org. Lett. 2019 Mar 21 6 1926-1929
- Stereospecific Stille Cross-Couplings Using Mn(II)Cl2.
- Dakarapu R, Falck JR J. Org. Chem. 2018 Jan
- Cytochrome P450 monooxygenase lipid metabolites are significant second messengers in the resolution of choroidal neovascularization.
- Hasegawa E, Inafuku S, Mulki L, Okunuki Y, Yanai R, Smith KE, Kim CB, Klokman G, Bielenberg DR, Puli N, Falck JR, Husain D, Miller JW, Edin ML, Zeldin DC, Lee KSS, Hammock BD, Schunck WH, Connor KM Proc. Natl. Acad. Sci. U.S.A. 2017 Aug
- 20-HETE Signals Through G Protein-Coupled Receptor GPR75 (Gq) to Affect Vascular Function and Trigger Hypertension
- Garcia, V.; Gilani, A.; Shkolnik, B.; Pandey, V.; Zhang, F.F.; Dakarapu, R.; Gandham, S.K.; Reddy, N.R.; Graves, J.P.; Gruzdev, A.; Zeldin, D.C.; Capdevila, J.H.; Falck, J.R.; Schwartzman, M.L. Cir. Res. 2017 120 1776-1788
- Dirhodium-catalyzed C-H arene amination using hydroxylamines.
- Paudyal MP, Adebesin AM, Burt SR, Ess DH, Ma Z, Kürti L, Falck JR Science 2016 Sep 353 6304 1144-7
- Direct Stereospecific Synthesis of Unprotected N-H and N-Me Aziridines from Olefins
- Jat, J.L.; Paudyal, M.P.; Gao, H.; Xu, Q.-L.; Yousufuddin, M.; Devarajan, D.; Ess, D.H.; Kürti, L.; Falck, J.R. Science 2014 343 61-65
Honors & Awards
- American Chemical Society
Wilfred T. Doherty Award (1996) - Winter Eicosanoid Conference
Special Recognition Award (1996) - Phi Kappa Phi Honarary Society
(1973) - National Science Foundation
Trainee (1970)
Professional Associations/Affiliations
- American Chemical Society
- Royal Society of Chemistry (U.K.)