Tiffany Simms-Waldrip, M.D., is an Associate Professor in the Department of Pediatrics at UT Southwestern Medical Center. She specializes in pediatric hematology-oncology and focuses her research on hematopoietic stem cell transplant, transplant for bone marrow failure syndromes, and graft-versus-host disease.

Dr. Simms-Waldrip earned her medical degree at Texas Tech University Health Sciences Center. She performed her residency in pediatrics at UCLA Medical Center, where she also completed a fellowship in pediatric hematology-oncology.

Certified by the American Board of Pediatrics in pediatric hematology-oncology, she joined the UT Southwestern faculty in 2010.

Dr. Simms-Waldrip is the Clinical Director of Pediatric Hematopoietic Stem Cell Transplant (HSCT) at UT Southwestern and Children’s Medical Center Dallas. She also serves as the HSCT Education Coordinator and HSCT Bone Marrow Failure Physician at both institutions.

She is a member of the American Society for Transplantation and Cellular Therapy and serves on numerous committees, including as Chair of the Tissue and Transfusion Utilization Committee at Children’s. In addition, she is a Pediatrics Residency Program mentor at UTSW.

She has published numerous academic articles.


Medical School
Texas Tech University Health Sciences Center (2004)
University of California, Los Angeles (2007), Pediatrics
University of California, Los Angeles (2010), Pediatric Hematology/oncology

Research Interest

  • Graft-versus-host disease
  • Hematopoiesis
  • Transplantation in bone marrow failure syndromes


Featured Publications LegendFeatured Publications

Volumetric Modulated Arc Therapy Enabled Total Body Irradiation (VMAT-TBI): Six-year Clinical Experience and Treatment Outcomes.
Zhang-Velten ER, Parsons D, Lee P, Chambers E, Abdulrahman R, Desai NB, Dan T, Wardak Z, Timmerman R, Vusirikala M, Patel P, Simms-Waldrip T, Aquino V, Koh A, Tan J, Iqbal Z, Zhang Y, Reynolds R, Chiu T, Joo M, Hrycushko B, Ouyang L, Lamphier R, Yan Y, Jiang SB, Kumar KA, Gu X, Transplant Cell Ther 2021 Nov
Food for Gut: Microbiota Fuels Immune Reconstitution after BMT.
Simms-Waldrip TR, Koh AY Cell Host Microbe 2018 Apr 23 4 423-424
Antibiotic-Induced Depletion of Anti-Inflammatory Clostridia is Associated with the Development of GVHD in Pediatric Stem Cell Transplant Patients.
Simms-Waldrip TR, Sunkersett G, Coughlin LA, Savani MR, Arana C, Kim J, Kim M, Zhan X, Greenberg DE, Xie Y, Davies SM, Koh AY Biol. Blood Marrow Transplant. 2017 Feb
Activation of HIF-1a and LL-37 by commensal bacteria inhibits Candida albicans colonization.
Fan D, Coughlin LA, Neubauer MM, Kim J, Kim MS, Zhan X, Simms-Waldrip TR, Xie Y, Hooper LV, Koh AY Nat. Med. 2015 Jun
Invasive fungal infections in pediatric hematopoietic stem cell transplant patients.
Simms-Waldrip T, Rosen G, Nielsen-Saines K, Ikeda A, Brown B, Moore T Infect Dis (Lond) 2015 Apr 47 4 218-24
Nasal Endoscopy in the evaluation of prolonged febrile events in children undergoing hematopoietic stem cell transplantation
Aquino V, Holmes S, Olivarez K, DeMasi J, Simms-Waldrip TR, Koh AY, Siegel J Biology of Blood and Marrow Transplantation 2015 Feb 21 2 S242?S243
Incidence and outcome of rhinovirus in children undergoing hematopoietic stem cell transplantation
DeMasi J, Aquino V, Simms-Waldrip TR, Koh AY, Holmes S. Biology of Blood and Marrow Transplantation 2015 Feb 21 2 S248
Dramatic response to rituximab in a child with severe cold autoimmune hemolytic anemia arising after allogeneic hematopoietic SCT.
Simms-Waldrip T, Ikeda A, Goldfinger D, Moore T, Yuan S Bone Marrow Transplant. 2010 Jan 45 1 201-2
The aggresome pathway as a target for therapy in hematologic malignancies.
Simms-Waldrip T, Rodriguez-Gonzalez A, Lin T, Ikeda AK, Fu C, Sakamoto KM Mol. Genet. Metab. 2008 Jul 94 3 283-6
Role of the aggresome pathway in cancer: targeting histone deacetylase 6-dependent protein degradation.
Rodriguez-Gonzalez A, Lin T, Ikeda AK, Simms-Waldrip T, Fu C, Sakamoto KM Cancer Res. 2008 Apr 68 8 2557-60

Honors & Awards

  • ASBMT Clinical Research Training Scholar
  • NIH T32 Developmental Hematology Training Grant
  • AAP Resident Research Grant
  • Magna Cum Laude, Texas Christian University

Professional Associations/Affiliations

  • American Society for Transplantation and Cellular Therapy (2010)
  • American Society of Pediatric Hematology/Oncology (2009-2012)