Mauricio Delgado-Ayala, M.D. - Faculty Profile

Biography

Clinical Interests: Dr. Mauricio R. Delgado-Ayala specializes in the neurorehabilitation of children with motor disorders of central origin and neurogenetic disorders such as holoprosencephaly and tuberous sclerosis complex.

Leadership: In 2019, he became president of the American Academy for Cerebral Palsy and Developmental Medicine. He is a co-founder member of the Mexican Academy for Cerebral palsy and Neurodevelopmental Disabilities.

Background: Dr. Mauricio R. Delgado-Ayala received his medical degree from the University of Monterrey in Monterrey, Mexico. He did his postgraduate training in pediatrics and neurology at the University of Ottawa in Ottawa, Canada. He received certification in neurology with special competence in child neurology and neurophysiology from the American Board of Psychiatry and Neurology. Dr. Delgado-Ayala is a Fellow of the Royal College of Physicians of Canada.

Education

Research Interest

Publications

Germline mutation in POLR2A: a heterogeneous, multi-systemic developmental disorder characterized by transcriptional dysregulation: Hansen AW, Arora P, Khayat MM, Smith LJ, Lewis AM, Rossetti LZ, Jayaseelan J, Cristian I, Haynes D, DiTroia S, Meeks N, Delgado MR, Rosenfeld JA, Pais L, White SM, Meng Q, Pehlivan D, Liu P, Gingras MC, Wangler MF, Muzny DM, Lupski JR, Kaplan CD, Gibbs RA Human Genetics and Genomics Advances 2021 Jan 2
Defining the clinical, molecular and imaging spectrum of adaptor protein complex 4-associated hereditary spastic paraplegia: Ebrahimi-Fakhari D, Teinert J, Behne R, Wimmer M, D'Amore A, Eberhardt K, Brechmann B, Ziegler M, Jensen DM, Nagabhyrava P, Geisel G, Carmody E, Shamshad U, Dies KA, Yuskaitis CJ, Salussolia CL, Ebrahimi-Fakhari D, Pearson TS, Saffari A, Ziegler A, Kölker S, Volkmann J, Wiesener A, Bearden DR, Lakhani S, Segal D, Udwadia-Hegde A, Martinuzzi A, Hirst J, Perlman S, Takiyama Y, Xiromerisiou G, Vill K, Walker WO, Shukla A, Dubey Gupta R, Dahl N, Aksoy A, Verhelst H, Delgado MR, Kremlikova Pourova R, Sadek AA, Elkhateeb NM, Blumkin L, Brea-Fernández AJ, Dacruz-Álvarez D, Smol T, Ghoumid J, Miguel D, Heine C, Schlump JU, Langen H, Baets J, Bulk S, Darvish H, Bakhtiari S, Kruer MC, Lim-Melia E, Aydinli N, Alanay Y, El-Rashidy O, Nampoothiri S, Patel C, Beetz C, Bauer P, Yoon G, Guillot M, Miller SP, Bourinaris T, Houlden H, Robelin L, Anheim M, Alamri AS, Mahmoud AA, Inaloo S, Habibzadeh P, Faghihi MA, Jansen AC, Brock S, Roubertie A, Darras BT, Agrawal PB, Santorelli FM, Gleeson J, Zaki MS, Sheikh SI, Bennett JT, Sahin M Brain 2020 Oct 143 2929-2944
Duration of Symptom Relief Between Injections for AbobotulinumtoxinA (Dysport®) in Spastic Paresis and Cervical Dystonia: Comparison of Evidence From Clinical Studies: Esquenazi A, Delgado MR, Hauser RA, Picaut P, Foster K, Lysandropoulos A, Gracies JM Frontiers in Neurology 2020 Sep 11
Neural and non-neural contributions to ankle spasticity in children with cerebral palsy: Xu D, Wu YN, Gaebler-Spira D, Gao F, Clegg NJ, Delgado MR, Zhang LQ Developmental Medicine and Child Neurology 2020 Sep 62 1040-1046
Efficacy of Repeat AbobotulinumtoxinA (Dysport®) Injections in Improving Gait in Children with Spastic Cerebral Palsy: Dursun N, Bonikowski M, Dabrowski E, Matthews D, Gormley M, Tilton A, Carranza J, Grandoulier AS, Picaut P, Delgado MR Developmental Neurorehabilitation 2020 Aug 23 368-374
GATAD2B-associated neurodevelopmental disorder (GAND): clinical and molecular insights into a NuRD-related disorder: Author Collaboration TU, Shieh C, Jones N, Vanle B, Au M, Huang AY, Silva AP, Lee H, Douine ED, Otero MG, Choi A, Grand K, Taff IP, Delgado MR, Hajianpour MJ, Seeley A, Rohena L, Vernon H, Gripp KW, Vergano SA, Mahida S, Naidu S, Sousa AB, Wain KE, Challman TD, Beek G, Basel D, Ranells J, Smith R, Yusupov R, Freckmann ML, Ohden L, Davis-Keppen L, Chitayat D, Dowling JJ, Finkel R, Dauber A, Spillmann R, Pena LD, Metcalfe K, Splitt M, Lachlan K, McKee SA, Hurst J, Fitzpatrick DR, Morton JE, Cox H, Venkateswaran S, Young JI, Marsh ED, Nelson SF Genetics in Medicine 2020 May 22 878-888
Correction: GATAD2B-associated neurodevelopmental disorder (GAND): clinical and molecular insights into a NuRD-related disorder (Genetics in Medicine, (2020), 10.1038/s41436-019-0747-z): Author Collaboration TU, Shieh C, Jones N, Vanle B, Au M, Huang AY, Silva AP, Lee H, Douine ED, Otero MG, Choi A, Grand K, Taff IP, Delgado MR, Hajianpour MJ, Seeley A, Rohena L, Vernon H, Gripp KW, Vergano SA, Mahida S, Naidu S, Sousa AB, Wain KE, Challman TD, Beek G, Basel D, Ranells J, Smith R, Yusupov R, Freckmann ML, Ohden L, Davis-Keppen L, Chitayat D, Dowling JJ, Finkel R, Dauber A, Spillmann R, Pena LD, Metcalfe K, Splitt M, Lachlan K, McKee SA, Hurst J, Fitzpatrick DR, Morton JE, Cox H, Venkateswaran S, Young JI, Marsh ED, Nelson SF Genetics in Medicine 2020 Apr 22 822
Correction: DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract (Genetics in Medicine, (2019), 21, 12, (2755-2764), 10.1038/s41436-019-0576-0): Blackburn AT, Bekheirnia N, Uma VC, Corkins ME, Xu Y, Rosenfeld JA, Bainbridge MN, Yang Y, Liu P, Madan-Khetarpal S, Delgado MR, Hudgins L, Krantz I, Rodriguez-Buritica D, Wheeler PG, Al-Gazali L, Shamsi AM, Gomez-Ospina N, Chao HT, Mirzaa GM, Scheuerle AE, Kukolich MK, Scaglia F, Eng C, Willsey HR, Braun MC, Lamb DJ, Miller RK, Bekheirnia MR Genetics in Medicine 2020 Apr 22 821
Corrigendum: 2-Pyrrolidinone and Succinimide as Clinical Screening Biomarkers for GABA-Transaminase Deficiency: Anti-seizure Medications Impact Accurate Diagnosis (Frontiers in Neuroscience, (2019), 13, 10.3389/fnins.2019.00394): Kennedy AD, Pappan KL, Donti T, Delgado MR, Shinawi M, Pearson TS, Lalani SR, Craigen WJ, Sutton VR, Evans AM, Sun Q, Emrick LT, Elsea SH Frontiers in Neuroscience 2020 Jan 13
TBX6 missense variants expand the mutational spectrum in a non-Mendelian inheritance disease: Chen W, Lin J, Wang L, Li X, Zhao S, Liu J, Akdemir ZC, Zhao Y, Du R, Ye Y, Song X, Zhang Y, Yan Z, Yang X, Lin M, Shen J, Wang S, Gao N, Yang Y, Liu Y, Li W, Liu J, Zhang N, Yang X, Xu Y, Zhang J, Delgado MR, Posey JE, Qiu G, Rios JJ, Liu P, Wise CA, Zhang F, Wu Z, Lupski JR, Wu N Human mutation 2020 Jan 41 182-195

Books

Status Epilepticus. In Essential Guide to Pediatric Intensive Care

Delgado, MR (1990). St. Louis, Missouri, Quality Medical Publishers, Inc

Status Epilepticus. In Essentials of Pediatric Intensive Care

Delgado MR, Riela A (1996). St. Louis, Missouri, Quality Medical Publishers, Inc

Neurophysiological Testing in ICU. In Essentials of Pediatric Intensive Care

Sing B, Riela A, Delgado MR (1996). St. Louis, Missouri, Quality Medical Publishers, Inc.

Paralisis Cerebral: Estado Actual. In Desordenes Del Neurodesarrollo

Delgado MR (2001). Monterrey, N.L. México, Psicofarma S.A. de C.V.

The Use of Botulinum Toxin in Juvenile Cerebral Palsy. In Scientific and Therapeutic Aspects of Botulinum Toxin

Delgado MR (2002). NY, Lippincott Williams & Wilkins

Tratamiento Con Toxina Botulinica de la Espasticidad en Niños. In Toxina Botulinica Nuevas indicaciones terapeuticas

Delgado MR, Carranza del Rio J (2010). Buenos Aires, Argentina, Medica Panamericana

Honors & Awards

Best Doctors in America
(2017-2018)
Keynote Speaker at Commencement Exercises, Fall Class of 2010 University of Monterrey
(2010)
Best Doctors in America-Fifteen Edition
(2009)
FREDDDIE Award
Category Special People for video; Living with Hope: Understanding Holoprosencephaly. Associate Producer (2001)
Instituto De Seguridad y Servicios Sociales, Centro Medico nacional
Associate Professor of Pediatric Neurology (2000)
JCN/Decher Neuroscience Prize
(1998)
Keeper of the Flame Award; National Tuberous Sclerosis Association
(1998)
Gold Award; 5th International A.V. Epilepsy Festival
(1997)
Professional Advisor of the Year Award; Epilepsy Foundation of America
(1995)
Dr. H.M. Finlayson Award for the best clinical paper-Annual Canadian Neuropathology Meeting
(1984)

Professional Associations/Affiliations

Academia Mexicana para la Parálisis Cerebral y Trastornos del Neurodesarrollo (2015)
American Academy Cerebral Palsy Developmental Medicine (1996)
American Academy of Neurology (1981)
American Child Neurology Society (1985)
American Society of Neurorehabilitation (1990)
Canadian Association of Child Neurology (1985-2005)
Dallas County Medical Society (2011)
International Child Neurology Association (1990)
Professors of Child Neurology (1990-2017)
Royal College of Physicians of Canada (1987)
Sociedad Mexicana de Neurología Pediátrica (1990)
Texas Medical Assiociation (2011)