Education

Graduate School
Technical University of Munich (1971), Physics
Graduate School
Technical University of Munich (1974), Experimental Physics

Publications

Featured Publications LegendFeatured Publications

NMR structures of the selenoproteins Sep15 and SelM reveal redox activity of a new thioredoxin-like family.
A.D. Ferguson, V.M. Labunskyy, D.E. Fomenko, Y. Chelliah, D. Arac, C.A. Amezcua, J. Rizo, V.N. Gladyshev & J. Deisenhofer J. Biol. Chem February 2006 281 (6) 3536-3543
NMR structures of the selenoproteins Sep15 and SelM reveal redox activity of a new thioredoxin-like family.
Ferguson AD, Labunskyy VM, Fomenko DE, Araç D, Chelliah Y, Amezcua CA, Rizo J, Gladyshev VN, Deisenhofer J J. Biol. Chem. 2006 Feb 281 6 3536-43
Mechanistic insight into the allosteric activation of a ubiquitin-conjugating enzyme by RING-type ubiquitin ligases.
Ozkan E, Yu H, Deisenhofer J Proc. Natl. Acad. Sci. U.S.A. 2005 Dec 102 52 18890-5
Structure of the ectodomain of Drosophila peptidoglycan-recognition protein LCa suggests a molecular mechanism for pattern recognition.
Chang CI, Ihara K, Chelliah Y, Mengin-Lecreulx D, Wakatsuki S, Deisenhofer J Proc. Natl. Acad. Sci. U.S.A. 2005 Jul 102 29 10279-84
A Drosophila pattern recognition receptor contains a peptidoglycan docking groove and unusual L,D-carboxypeptidase activity.
Chang CI, Pili-Floury S, Hervé M, Parquet C, Chelliah Y, Lemaitre B, Mengin-Lecreulx D, Deisenhofer J PLoS Biol. 2004 Sep 2 9 E277
Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana.
Brautigam CA, Smith BS, Ma Z, Palnitkar M, Tomchick DR, Machius M, Deisenhofer J Proc. Natl. Acad. Sci. U.S.A. 2004 Aug 101 33 12142-7
Tetramerization and ATP binding by a protein comprising the A, B, and C domains of rat synapsin I.
Brautigam CA, Chelliah Y, Deisenhofer J J. Biol. Chem. 2004 Mar 279 12 11948-56
Metal import through microbial membranes.
Ferguson AD, Deisenhofer J Cell 2004 Jan 116 1 15-24
The low-density lipoprotein receptor: ligands, debates and lore.
Rudenko G, Deisenhofer J Curr. Opin. Struct. Biol. 2003 Dec 13 6 683-9
'MAD'ly phasing the extracellular domain of the LDL receptor: a medium-sized protein, large tungsten clusters and multiple non-isomorphous crystals.
Rudenko G, Henry L, Vonrhein C, Bricogne G, Deisenhofer J Acta Crystallogr. D Biol. Crystallogr. 2003 Nov 59 Pt 11 1978-86

Honors & Awards

  • Nobel Prize in Chemistry
    (shared with R. Huber and H. Michel) (1988)
  • Otto-Bayer-Preis
    (shared with H. Michel) (1988)
  • Biological Physics Prize of the American Physical Society
    (shared with H. Michel) (1986)

Professional Associations/Affiliations

  • Academia Europaea (1989)
  • American Association for the Advancement of Science (Fellow 1992)
  • American Crystallographic Association
  • German Academy of Natural Scientists Leopoldina (2003)
  • National Academy of Sciences (1997)