
Johann Deisenhofer, Ph.D.
Professor Emeritus
Endowed Title Regental Professor
School Medical School
Department Biophysics
Graduate Programs Molecular Biophysics
Education
- Graduate School
- Technical University of Munich (1971), Physics
- Graduate School
- Technical University of Munich (1974), Experimental Physics
Publications
Featured Publications
- Structure of the LDL receptor extracellular domain at endosomal pH.
- Rudenko, G., Henry, L., Henderson, K., Ichtchenko, K., Brown, M.S., Goldstein, J.L., and Deisenhofer, J. Science 2002 298 2353-2358
- The crystal structure of the cytochrome bc1 complex from bovine heart mitochondria.
- D. Xia, C.-A. Yu, H. Kim, J.-Z. Xia, A.M. Kachurin, L. Zhang, L. Yu & J. Deisenhofer Science 1997 277 60-66
- Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats.
- B. Kobe & J. Deisenhofer Nature 1993 366 751-756
- The photosynthetic reaction centre from the purple bacterium Rhodopseudomonas viridis.
- J. Deisenhofer & H. Michel EMBO J 1989 8 (8) 2149-2170
- Crystallographic refinement of the structure of bovine pancreatic trypsin inhibitor at 1.5 Å resolution.
- Deisenhofer, J., and Steigemann, W. Acta Crystallographica 1975 B31 238-250
- Crystal structure of Spot 14, a modulator of fatty acid synthesis.
- Colbert CL, Kim CW, Moon YA, Henry L, Palnitkar M, McKean WB, Fitzgerald K, Deisenhofer J, Horton JD, Kwon HJ Proc. Natl. Acad. Sci. U.S.A. 2010 Nov 107 44 18820-5
- A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae.
- Baxter RH, Steinert S, Chelliah Y, Volohonsky G, Levashina EA, Deisenhofer J Proc. Natl. Acad. Sci. U.S.A. 2010 Sep 107 39 16817-22
- Model of human low-density lipoprotein and bound receptor based on cryoEM.
- Ren G, Rudenko G, Ludtke SJ, Deisenhofer J, Chiu W, Pownall HJ Proc. Natl. Acad. Sci. U.S.A. 2010 Jan 107 3 1059-64
- Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol.
- Kwon HJ, Abi-Mosleh L, Wang ML, Deisenhofer J, Goldstein JL, Brown MS, Infante RE Cell 2009 Jun 137 7 1213-24
- Insights into pilus assembly and secretion from the structure and functional characterization of usher PapC.
- Huang Y, Smith BS, Chen LX, Baxter RH, Deisenhofer J Proc. Natl. Acad. Sci. U.S.A. 2009 May 106 18 7403-7
Honors & Awards
- Nobel Prize in Chemistry
(shared with R. Huber and H. Michel) (1988) - Otto-Bayer-Preis
(shared with H. Michel) (1988) - Biological Physics Prize of the American Physical Society
(shared with H. Michel) (1986)
Professional Associations/Affiliations
- Academia Europaea (1989)
- American Association for the Advancement of Science (Fellow 1992)
- American Crystallographic Association
- German Academy of Natural Scientists Leopoldina (2003)
- National Academy of Sciences (1997)