Johann Deisenhofer, Ph.D.

Graduate School

Technical University of Munich (1971), Physics

Graduate School

Technical University of Munich (1974), Experimental Physics

Featured Publications

Structure of the LDL receptor extracellular domain at endosomal pH.

Rudenko, G., Henry, L., Henderson, K., Ichtchenko, K., Brown, M.S., Goldstein, J.L., and Deisenhofer, J. Science 2002 298 2353-2358

The crystal structure of the cytochrome bc1 complex from bovine heart mitochondria.

D. Xia, C.-A. Yu, H. Kim, J.-Z. Xia, A.M. Kachurin, L. Zhang, L. Yu & J. Deisenhofer Science 1997 277 60-66

Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats.

B. Kobe & J. Deisenhofer Nature 1993 366 751-756

The photosynthetic reaction centre from the purple bacterium Rhodopseudomonas viridis.

J. Deisenhofer & H. Michel EMBO J 1989 8 (8) 2149-2170

Crystallographic refinement of the structure of bovine pancreatic trypsin inhibitor at 1.5 Å resolution.

Deisenhofer, J., and Steigemann, W. Acta Crystallographica 1975 B31 238-250

Crystal structure of Spot 14, a modulator of fatty acid synthesis.

Colbert CL, Kim CW, Moon YA, Henry L, Palnitkar M, McKean WB, Fitzgerald K, Deisenhofer J, Horton JD, Kwon HJ Proc. Natl. Acad. Sci. U.S.A. 2010 Nov 107 44 18820-5

A heterodimeric complex of the LRR proteins LRIM1 and APL1C regulates complement-like immunity in Anopheles gambiae.

Baxter RH, Steinert S, Chelliah Y, Volohonsky G, Levashina EA, Deisenhofer J Proc. Natl. Acad. Sci. U.S.A. 2010 Sep 107 39 16817-22

Model of human low-density lipoprotein and bound receptor based on cryoEM.

Ren G, Rudenko G, Ludtke SJ, Deisenhofer J, Chiu W, Pownall HJ Proc. Natl. Acad. Sci. U.S.A. 2010 Jan 107 3 1059-64

Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol.

Kwon HJ, Abi-Mosleh L, Wang ML, Deisenhofer J, Goldstein JL, Brown MS, Infante RE Cell 2009 Jun 137 7 1213-24

Insights into pilus assembly and secretion from the structure and functional characterization of usher PapC.

Huang Y, Smith BS, Chen LX, Baxter RH, Deisenhofer J Proc. Natl. Acad. Sci. U.S.A. 2009 May 106 18 7403-7

• Nobel Prize in Chemistry
  (shared with R. Huber and H. Michel) (1988)
• Otto-Bayer-Preis
  (shared with H. Michel) (1988)
• Biological Physics Prize of the American Physical Society
  (shared with H. Michel) (1986)

• Academia Europaea (1989)
• American Association for the Advancement of Science (Fellow 1992)
• American Crystallographic Association
• German Academy of Natural Scientists Leopoldina (2003)
• National Academy of Sciences (1997)