Biography

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Dr. de Lemos is Professor of medicine and holds the Sweetheart Ball-Kern Wildenthal, MD, PhD Distinguished Chair in Cardiology.  He is the Cardiology Service Chief at Parkland Memorial Hospital where he also serves as CCU Director.  He was the director of the Cardiology Fellowship at UT Southwestern from 2005-2011. He is an active investigator in the Donald W. Reynolds Cardiovascular Research Center at UT Southwestern, and the Medical Director of the Dallas Heart Study.   He has chaired or co-chaired several research planning committees at UT Southwestern.  His primary research interests are in early detection, risk assessment and management of cardiovascular disease, with a particular focus on the role of cardiovascular biomarkers.  His research has evaluated existing biomarkers such as B-type natriuretic peptide, C-reactive protein and cardiac troponins as well as novel biomarkers reflecting biological pathways of disease.  He was the lead author of the Z phase of the A to Z trial, an international trial investigating different cholesterol lowering strategies in patients with acute coronary syndromes.  He graduated from Harvard Medical School and completed an Internal Medicine Residency at UT Southwestern Medical Center, where he also served as Chief Medical Resident.  He completed a fellowship in Cardiovascular Medicine and served on the faculty at the Brigham and Women’s Hospital before returning to UT Southwestern Medical School.  He has served on multiple committees of the AHA and ACC and is on the editorial board of the Journal of the American College of Cardiology, the American Journal of Cardiology and the American Heart Journal.  He has mentored >25 post-doctoral research trainees and has authored or coauthored over 250 manuscripts or book chapters and won several teaching awards. He sees patients with a broad range of cardiac problems, but specializes in those with chest pain and coronary artery disease.

Education

Medical School
Harvard Medical School (1992)
Internship
UT Southwestern Medical Center (1993), Internal Medicine
Residency
UT Southwestern Medical Center (1995), Internal Medicine
Chief Resident
UT Southwestern Medical Center (1996), Internal Medicine
Fellowship
Harvard Medical School (1999), Cardiology

Research Interest

  • Acute Coronary Syndromes
  • Cardiac Biomarkers
  • Lipid Lowering Therapy
  • Screening for Cardiovascular Disease

Publications

Featured Publications LegendFeatured Publications

The association between peptidoglycan recognition protein-1 and coronary and peripheral atherosclerosis: Observations from the Dallas Heart Study.
Rohatgi A, Ayers CR, Khera A, McGuire DK, Das SR, Matulevicius S, Timaran CH, Rosero EB, de Lemos JA Atherosclerosis 2009 Apr 203 2 569-75
Systems-based improvement in door-to-balloon times at a large urban teaching hospital: a follow-up study from Parkland Health and Hospital System.
Parikh SV, Treichler DB, DePaola S, Sharpe J, Valdes M, Addo T, Das SR, McGuire DK, de Lemos JA, Keeley EC, Warner JJ, Holper EM Circ Cardiovasc Qual Outcomes 2009 Mar 2 2 116-22
Association of cystatin C with left ventricular structure and function: the Dallas Heart Study.
Patel PC, Ayers CR, Murphy SA, Peshock R, Khera A, de Lemos JA, Balko JA, Gupta S, Mammen PP, Drazner MH, Markham DW Circ Heart Fail 2009 Mar 2 2 98-104
A randomized controlled trial of a paclitaxel-eluting stent versus a similar bare-metal stent in saphenous vein graft lesions the SOS (Stenting of Saphenous Vein Grafts) trial.
Brilakis ES, Lichtenwalter C, de Lemos JA, Roesle M, Obel O, Haagen D, Saeed B, Gadiparthi C, Bissett JK, Sachdeva R, Voudris VV, Karyofillis P, Kar B, Rossen J, Fasseas P, Berger P, Banerjee S J. Am. Coll. Cardiol. 2009 Mar 53 11 919-28
Hemodynamics and epoprostenol use are associated with thrombocytopenia in pulmonary arterial hypertension.
Chin KM, Channick RN, de Lemos JA, Kim NH, Torres F, Rubin LJ Chest 2009 Jan 135 1 130-6
Detection of acute changes in circulating troponin in the setting of transient stress test-induced myocardial ischaemia using an ultrasensitive assay: results from TIMI 35.
Sabatine MS, Morrow DA, de Lemos JA, Jarolim P, Braunwald E Eur. Heart J. 2009 Jan 30 2 162-9
Cardiovascular risk indicators and perceived race/ethnic discrimination in the Dallas Heart Study.
Albert MA, Ravenell J, Glynn RJ, Khera A, Halevy N, de Lemos JA Am. Heart J. 2008 Dec 156 6 1103-9
Association of lipoprotein-associated phospholipase A2 mass and activity with coronary and aortic atherosclerosis: findings from the Dallas Heart Study.
Brilakis ES, Khera A, Saeed B, Banerjee S, McGuire DK, Murphy SA, de Lemos JA Clin. Chem. 2008 Dec 54 12 1975-81
Association between renal function and circulating levels of natriuretic peptides (from the Dallas Heart Study).
Das SR, Abdullah SM, Leonard D, Drazner MH, Khera A, McGuire DK, de Lemos JA Am. J. Cardiol. 2008 Nov 102 10 1394-8
The association between plasma caspase-3, atherosclerosis, and vascular function in the Dallas Heart Study.
Matulevicius S, Rohatgi A, Khera A, Das SR, Owens A, Ayers CR, Timaran CH, Rosero EB, Drazner MH, Peshock RM, de Lemos JA Apoptosis 2008 Oct 13 10 1281-9

Books

Featured Books Legend Featured Books

Unstable Angina and Non-ST Elevation Myocardial Infarction. In Hurst's the Heart, 13th ed

de Lemos JA, O'Rourke RA, Harrington RA (2011). McGraw Hill

ST Elevation Myocardial infarction. In Irwin and Rippe?s Intensive Care Medicine 7th edition

de Lemos JA and Morrow DA (2011). William and Wilkins

Honors & Awards

  • Simon Dack Award for Medical Publications
    Journal of the American College of Cardiology (2012)
  • Association of University Cardiologists
    (2011)
  • Best Doctors in Dallas, Cardiology
    D Magazine (2011)
  • Core Clerkship Teaching Award
    UT Southwestern (2011)
  • Super Doctors, Cardiology
    Texas Monthly (2011)
  • Best Doctors in Dallas, Cardiology
    D Magazine (2010)
  • Super Doctors, Cardiology
    Texas Monthly (2010)
  • Sweetheart Ball-Kern Wildenthal MD, PhD Distinguished Chair
    Distinguished Chair in Cardiology (2009)
  • Elite Reviewer
    Journal of the American College of Cardiology (2006)
  • Best Doctors in Dallas, Cardiology
    D Magazine (2005)
  • Internal Medicine Teaching Award
    Excellence in Teaching (2005)
  • Eugene Braunwald Fellowship
    Excellence in Clinical Research, Brigham and Women’s Hospital (1999)
  • Soma Weiss Award
    Excellence in Teaching, Brigham and Women’s Hospital (1997)

Professional Associations/Affiliations

  • Society of Chest Pain Physicians (2011)
  • AHA/ACC ST Elevation MI Guideline Committee (2010-2012)
  • Chair, Research and Publications Committee (2010)
  • American Heart Association (1998)
  • American College of Cardiology (1996)