Download Curriculum Vitae

Dr. de Lemos is Professor of medicine and holds the Sweetheart Ball-Kern Wildenthal, MD, PhD Distinguished Chair in Cardiology.  He is the Cardiology Service Chief at Parkland Memorial Hospital where he also serves as CCU Director.  He was the director of the Cardiology Fellowship at UT Southwestern from 2005-2011. He is an active investigator in the Donald W. Reynolds Cardiovascular Research Center at UT Southwestern, and the Medical Director of the Dallas Heart Study.   He has chaired or co-chaired several research planning committees at UT Southwestern.  His primary research interests are in early detection, risk assessment and management of cardiovascular disease, with a particular focus on the role of cardiovascular biomarkers.  His research has evaluated existing biomarkers such as B-type natriuretic peptide, C-reactive protein and cardiac troponins as well as novel biomarkers reflecting biological pathways of disease.  He was the lead author of the Z phase of the A to Z trial, an international trial investigating different cholesterol lowering strategies in patients with acute coronary syndromes.  He graduated from Harvard Medical School and completed an Internal Medicine Residency at UT Southwestern Medical Center, where he also served as Chief Medical Resident.  He completed a fellowship in Cardiovascular Medicine and served on the faculty at the Brigham and Women’s Hospital before returning to UT Southwestern Medical School.  He has served on multiple committees of the AHA and ACC and is on the editorial board of the Journal of the American College of Cardiology, the American Journal of Cardiology and the American Heart Journal.  He has mentored >25 post-doctoral research trainees and has authored or coauthored over 250 manuscripts or book chapters and won several teaching awards. He sees patients with a broad range of cardiac problems, but specializes in those with chest pain and coronary artery disease.


Medical School
Harvard Medical School (1992)
UT Southwestern Medical Center (1993), Internal Medicine
UT Southwestern Medical Center (1995), Internal Medicine
Chief Resident
UT Southwestern Medical Center (1996), Internal Medicine
Harvard Medical School (1999), Cardiology

Research Interest

  • Acute Coronary Syndromes
  • Cardiac Biomarkers
  • Lipid Lowering Therapy
  • Screening for Cardiovascular Disease


Featured Publications LegendFeatured Publications

A 4-tiered classification of left ventricular hypertrophy based on left ventricular geometry: the Dallas heart study.
Khouri MG, Peshock RM, Ayers CR, de Lemos JA, Drazner MH Circ Cardiovasc Imaging 2010 Mar 3 2 164-71
An evidence-based algorithm for the use of B-type natriuretic testing in acute coronary syndromes.
McCullough PA, Peacock WF, O'Neil B, de Lemos JA, Lepor NE, Berkowitz R Rev Cardiovasc Med 2010 11 Suppl 2 S51-65
Capturing the pathophysiology of acute coronary syndromes with circulating biomarkers.
McCullough PA, Peacock WF, O'Neil B, de Lemos JA Rev Cardiovasc Med 2010 11 Suppl 2 S3-12
Natriuretic peptides in the prognosis and management of acute coronary syndromes.
de Lemos JA, Peacock WF, McCullough PA Rev Cardiovasc Med 2010 11 Suppl 2 S24-34
Should we focus on novel risk markers and screening tests to better predict and prevent cardiovascular disease? Point.
Enriquez JR, de Lemos JA Prev Cardiol 2010 13 4 152-9
A sensitive cardiac troponin T assay in stable coronary artery disease.
Omland T, de Lemos JA, Sabatine MS, Christophi CA, Rice MM, Jablonski KA, Tjora S, Domanski MJ, Gersh BJ, Rouleau JL, Pfeffer MA, Braunwald E N. Engl. J. Med. 2009 Dec 361 26 2538-47
Keeping our eyes on the prize: low density lipoprotein cholesterol.
de Lemos JA, Khera A Am. J. Cardiol. 2009 Dec 104 12 1697-8
Acute decline in renal function, inflammation, and cardiovascular risk after an acute coronary syndrome.
Mielniczuk LM, Pfeffer MA, Lewis EF, Blazing MA, de Lemos JA, Mohanavelu S, Rouleau J, Fox K, Pedersen TR, Califf RM Clin J Am Soc Nephrol 2009 Nov 4 11 1811-7
Differential associations between soluble cellular adhesion molecules and atherosclerosis in the Dallas Heart Study: a distinct role for soluble endothelial cell-selective adhesion molecule.
Rohatgi A, Owens AW, Khera A, Ayers CR, Banks K, Das SR, Berry JD, McGuire DK, de Lemos JA Arterioscler. Thromb. Vasc. Biol. 2009 Oct 29 10 1684-90
Newer biomarkers in heart failure.
Gupta S, Drazner MH, de Lemos JA Heart Fail Clin 2009 Oct 5 4 579-88


Featured Books Legend Featured Books

Unstable Angina and Non-ST Elevation Myocardial Infarction. In Hurst's the Heart, 13th ed

de Lemos JA, O'Rourke RA, Harrington RA (2011). McGraw Hill

ST Elevation Myocardial infarction. In Irwin and Rippe?s Intensive Care Medicine 7th edition

de Lemos JA and Morrow DA (2011). William and Wilkins

Honors & Awards

  • Simon Dack Award for Medical Publications
    Journal of the American College of Cardiology (2012)
  • Association of University Cardiologists
  • Best Doctors in Dallas, Cardiology
    D Magazine (2011)
  • Core Clerkship Teaching Award
    UT Southwestern (2011)
  • Super Doctors, Cardiology
    Texas Monthly (2011)
  • Best Doctors in Dallas, Cardiology
    D Magazine (2010)
  • Super Doctors, Cardiology
    Texas Monthly (2010)
  • Sweetheart Ball-Kern Wildenthal MD, PhD Distinguished Chair
    Distinguished Chair in Cardiology (2009)
  • Elite Reviewer
    Journal of the American College of Cardiology (2006)
  • Best Doctors in Dallas, Cardiology
    D Magazine (2005)
  • Internal Medicine Teaching Award
    Excellence in Teaching (2005)
  • Eugene Braunwald Fellowship
    Excellence in Clinical Research, Brigham and Women’s Hospital (1999)
  • Soma Weiss Award
    Excellence in Teaching, Brigham and Women’s Hospital (1997)

Professional Associations/Affiliations

  • Society of Chest Pain Physicians (2011)
  • AHA/ACC ST Elevation MI Guideline Committee (2010-2012)
  • Chair, Research and Publications Committee (2010)
  • American Heart Association (1998)
  • American College of Cardiology (1996)