Biography

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Dr. de Lemos is Professor of medicine and holds the Sweetheart Ball-Kern Wildenthal, MD, PhD Distinguished Chair in Cardiology.  He is the Cardiology Service Chief at Parkland Memorial Hospital where he also serves as CCU Director.  He was the director of the Cardiology Fellowship at UT Southwestern from 2005-2011. He is an active investigator in the Donald W. Reynolds Cardiovascular Research Center at UT Southwestern, and the Medical Director of the Dallas Heart Study.   He has chaired or co-chaired several research planning committees at UT Southwestern.  His primary research interests are in early detection, risk assessment and management of cardiovascular disease, with a particular focus on the role of cardiovascular biomarkers.  His research has evaluated existing biomarkers such as B-type natriuretic peptide, C-reactive protein and cardiac troponins as well as novel biomarkers reflecting biological pathways of disease.  He was the lead author of the Z phase of the A to Z trial, an international trial investigating different cholesterol lowering strategies in patients with acute coronary syndromes.  He graduated from Harvard Medical School and completed an Internal Medicine Residency at UT Southwestern Medical Center, where he also served as Chief Medical Resident.  He completed a fellowship in Cardiovascular Medicine and served on the faculty at the Brigham and Women’s Hospital before returning to UT Southwestern Medical School.  He has served on multiple committees of the AHA and ACC and is on the editorial board of the Journal of the American College of Cardiology, the American Journal of Cardiology and the American Heart Journal.  He has mentored >25 post-doctoral research trainees and has authored or coauthored over 250 manuscripts or book chapters and won several teaching awards. He sees patients with a broad range of cardiac problems, but specializes in those with chest pain and coronary artery disease.

Education

Medical School
Harvard Medical School (1992)
Internship
UT Southwestern Medical Center (1993), Internal Medicine
Residency
UT Southwestern Medical Center (1995), Internal Medicine
Chief Resident
UT Southwestern Medical Center (1996), Internal Medicine
Fellowship
Harvard Medical School (1999), Cardiology

Research Interest

  • Acute Coronary Syndromes
  • Cardiac Biomarkers
  • Lipid Lowering Therapy
  • Screening for Cardiovascular Disease

Publications

Featured Publications LegendFeatured Publications

Association of troponin T, detected with highly sensitive assay, and outcomes in infective endocarditis.
Stancoven AB, Shiue AB, Khera A, Pinkston K, Hashim IA, Wang A, de Lemos JA, Peterson GE Am. J. Cardiol. 2011 Aug 108 3 416-20
Risk of incident diabetes with intensive-dose compared with moderate-dose statin therapy: a meta-analysis.
Preiss D, Seshasai SR, Welsh P, Murphy SA, Ho JE, Waters DD, DeMicco DA, Barter P, Cannon CP, Sabatine MS, Braunwald E, Kastelein JJ, de Lemos JA, Blazing MA, Pedersen TR, Tikkanen MJ, Sattar N, Ray KK JAMA 2011 Jun 305 24 2556-64
Myocardial ischemia induced by rapid atrial pacing causes troponin T release detectable by a highly sensitive assay: insights from a coronary sinus sampling study.
Turer AT, Addo TA, Martin JL, Sabatine MS, Lewis GD, Gerszten RE, Keeley EC, Cigarroa JE, Lange RA, Hillis LD, de Lemos JA J. Am. Coll. Cardiol. 2011 Jun 57 24 2398-405
Assessment of adiponectin and the risk of recurrent cardiovascular events in patients presenting with an acute coronary syndrome: observations from the Pravastatin Or atorVastatin Evaluation and Infection Trial-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIMI 22).
Wilson SR, Sabatine MS, Wiviott SD, Ray KK, De Lemos JA, Zhou S, Rifai N, Cannon CP, Morrow DA Am. Heart J. 2011 Jun 161 6 1147-55.e1
Recurrent cardiovascular events with paclitaxel-eluting versus bare-metal stents in saphenous vein graft lesions: insights from the SOS (Stenting of Saphenous Vein Grafts) trial.
Michael TT, Abdel-karim AR, Papayannis A, Lichtenwalter C, de Lemos JA, Obel O, Addo T, Roesle M, Haagen D, Rangan BV, Saeed B, Bissett JK, Sachdeva R, Voudris VV, Karyofillis P, Kar B, Rossen J, Fasseas P, Berger PB, Banerjee S, Brilakis ES J Invasive Cardiol 2011 Jun 23 6 216-9
Highly sensitive troponin assays and the cardiology community: a love/hate relationship?
de Lemos JA, Morrow DA, deFilippi CR Clin. Chem. 2011 Jun 57 6 826-9
Risk scores versus natriuretic peptides for identifying prevalent stage B heart failure.
Gupta S, Rohatgi A, Ayers CR, Patel PC, Matulevicius SA, Peshock RM, Markham DW, de Lemos JA, Berry JD, Drazner MH Am. Heart J. 2011 May 161 5 923-930.e2
Lifetime risks for cardiovascular disease mortality by cardiorespiratory fitness levels measured at ages 45, 55, and 65 years in men. The Cooper Center Longitudinal Study.
Berry JD, Willis B, Gupta S, Barlow CE, Lakoski SG, Khera A, Rohatgi A, de Lemos JA, Haskell W, Lloyd-Jones DM J. Am. Coll. Cardiol. 2011 Apr 57 15 1604-10
Cardiorespiratory fitness and classification of risk of cardiovascular disease mortality.
Gupta S, Rohatgi A, Ayers CR, Willis BL, Haskell WL, Khera A, Drazner MH, de Lemos JA, Berry JD Circulation 2011 Apr 123 13 1377-83
Cardiac troponin T measured by a highly sensitive assay predicts coronary heart disease, heart failure, and mortality in the Atherosclerosis Risk in Communities Study.
Saunders JT, Nambi V, de Lemos JA, Chambless LE, Virani SS, Boerwinkle E, Hoogeveen RC, Liu X, Astor BC, Mosley TH, Folsom AR, Heiss G, Coresh J, Ballantyne CM Circulation 2011 Apr 123 13 1367-76

Books

Featured Books Legend Featured Books

Unstable Angina and Non-ST Elevation Myocardial Infarction. In Hurst's the Heart, 13th ed

de Lemos JA, O'Rourke RA, Harrington RA (2011). McGraw Hill

ST Elevation Myocardial infarction. In Irwin and Rippe?s Intensive Care Medicine 7th edition

de Lemos JA and Morrow DA (2011). William and Wilkins

Honors & Awards

  • Simon Dack Award for Medical Publications
    Journal of the American College of Cardiology (2012)
  • Association of University Cardiologists
    (2011)
  • Best Doctors in Dallas, Cardiology
    D Magazine (2011)
  • Core Clerkship Teaching Award
    UT Southwestern (2011)
  • Super Doctors, Cardiology
    Texas Monthly (2011)
  • Best Doctors in Dallas, Cardiology
    D Magazine (2010)
  • Super Doctors, Cardiology
    Texas Monthly (2010)
  • Sweetheart Ball-Kern Wildenthal MD, PhD Distinguished Chair
    Distinguished Chair in Cardiology (2009)
  • Elite Reviewer
    Journal of the American College of Cardiology (2006)
  • Best Doctors in Dallas, Cardiology
    D Magazine (2005)
  • Internal Medicine Teaching Award
    Excellence in Teaching (2005)
  • Eugene Braunwald Fellowship
    Excellence in Clinical Research, Brigham and Women’s Hospital (1999)
  • Soma Weiss Award
    Excellence in Teaching, Brigham and Women’s Hospital (1997)

Professional Associations/Affiliations

  • Society of Chest Pain Physicians (2011)
  • AHA/ACC ST Elevation MI Guideline Committee (2010-2012)
  • Chair, Research and Publications Committee (2010)
  • American Heart Association (1998)
  • American College of Cardiology (1996)