Kathleen Ludwig, M.D. Titles and Appointments Associate Professor Schools Medical School Departments Pediatrics You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Dr. Ludwig is a board-certified pediatric oncologist, with a special interest in the care of patients with leukemia, lymphoma, relapsed leukemia, or lymphadenopathy, as well as managing general pediatric oncology disorders. She also devotes a dedicated part of her practice to treating patients with vascular anomalies. She is an active member of the Children’s Oncology Group and serves as the institutional principal investigator for numerous early phase I trials aiming to improve survival in patients with refractory/relapsed leukemia. Dr. Ludwig feels that families play a vital role in the care of a child with cancer and works with them to provide the best, most informed care possible. Education Medical School Loyola University Chicago Stritch School of Medicine (2009) Residency UT Southwestern/Children's Medical Center (2012), Pediatrics Fellowship UT Southwestern/Children's Medical Center (2015), Pediatric Hematology/oncology Research Interest Leukemia Vascular Anomalies Publications A Case Series of Peritoneal Mesothelioma in Pediatric Patients Merritt A, Ludwig K, Polanco PM, Sengupta A, Sadanand A Journal of Pediatric Hematology/Oncology 2026 Mar 48 e105-e108 An analysis of diagnostic metabolomic profiles associated with hepatotoxicity during childhood ALL induction therapy Mason EJ, Crain AM, Scheurer ME, Lupo PJ, Rabin KR, Taylor OA, Roberts M, Woodhouse JP, Chavana A, Ludwig K, Klesse L, Heym K, Griffin T, Erana R, Bernini JC, Gramatges MM, Yi JS, Pruitt SL, Bernhardt MB, Zhu H, Mittelman SD, Huynh V, Orgel E, Schraw JM, Brown AL Blood Advances 2025 Nov 9 5802-5810 Prediction of methotrexate neurotoxicity using clinical, sociodemographic, and area-based information in children with acute lymphoblastic leukemia Harris RD, Taylor OA, Gramatges MM, Hughes AE, Zobeck M, Pruitt S, Bernhardt MB, Chavana A, Huynh V, Ludwig K, Klesse L, Heym K, Griffin T, Erana R, Bernini JC, Choi A, Ohno Y, Richard MA, Morrison AC, Chen H, Yu B, Lupo PJ, Rabin KR, Scheurer ME, Brown AL Oncologist 2025 Jun 30 Larotrectinib for Newly Diagnosed Infantile Fibrosarcoma and Other Pediatric NTRK Fusion-Positive Solid Tumors (Children's Oncology Group ADVL1823) Laetsch TW, Voss S, Ludwig K, Hall D, Barkauskas DA, Dubois SG, Ronan J, Rudzinski ER, Memken A, Robinson K, Sorger J, Reid JM, Bhatla T, Crompton BD, Church AJ, Fox E, Weigel BJ Journal of Clinical Oncology 2025 Apr 43 1188-1197 Evaluation of methotrexate Pharmacogenomic variation to predict acute neurotoxicity in children with acute lymphoblastic leukemia Harris RD, Taylor OA, Gramatges MM, Hughes AE, Zobeck M, Pruitt S, Bernhardt MB, Chavana A, Huynh V, Ludwig K, Klesse L, Heym K, Griffin T, Erana R, Bernini JC, Choi A, Ohno Y, Richard MA, Morrison AC, Chen H, Yu B, Lupo PJ, Rabin K, Scheurer ME, Brown AL Pharmacotherapy 2025 Jan 45 4-11 Phase II Study of Samotolisib in Children and Young Adults With Tumors Harboring Phosphoinositide 3-Kinase/Mammalian Target of Rapamycin Pathway Alterations: Pediatric MATCH APEC1621D Laetsch TW, Ludwig K, Williams PM, Roy-Chowdhuri S, Patton DR, Coffey B, Reid JM, Piao J, Saguilig L, Alonzo TA, Berg SL, Mhlanga J, Fox E, Weigel BJ, Hawkins DS, Mooney MM, Takebe N, Tricoli JV, Janeway KA, Seibel NL, Parsons DW JCO Precision Oncology 2024 Sep 8 Genomic heterogeneity within B/T mixed phenotype acute leukemia in a context of an immunophenotype Zheng R, Fuda F, Gagan J, Weinberg OK, Koduru P, Cantu M, Ludwig K, Truscott JM, Collins R, Chung S, Madanat YF, Chen W Leukemia Research Reports 2024 Jan 21 Early therapy with sirolimus reduces size of a large solid renal mass but not seizure activity in an infant with tuberous sclerosis Hani SB, Artunduaga M, Ludwig K, Bissler JJ, Wolf MT Journal of Nephrology 2024 Jan 37 203-205 Recent progress in the treatment of cancer in children Butler E, Ludwig K, Pacenta HL, Klesse LJ, Watt TC, Laetsch TW CA Cancer Journal for Clinicians 2021 Jul 71 315-332 Giant congenital melanocytic nevus treated with trametinib Mir A, Agim NG, Kane AA, Josephs SC, Park JY, Ludwig K Pediatrics 2019 Mar 143 Results 1-10 of 13 1 2 Next Last Honors & Awards Best Pediatric SubspecialistD-Magazine (2021-2023) Best Poster awardUT Southwestern Pediatric Fellow's Research Symposium (2015) Best Basic Science AwardAnnual Surgical Research Forum, UT Southwestern (2014) Above-and-Beyond Recognition for ExcellenceUT Southwestern Pediatric Residency Program (2010) Professional Associations/Affiliations American Society of Clinical Oncology (2013) American Society of Hematology (2013) American Society of Pediatric Hematology/Oncology (2013) Childrens Medical Center Oncology Group (2013)
