
Sarah Comerford, Ph.D.
Assistant Professor
Department Molecular Genetics
Education
- Undergraduate
- University of London - England (1982), Biochemistry
- Graduate School
- University of London - England (1991), Biology
Research Interest
- Oncogenes, transformation, cell growth and apoptosis.
- PI3K/Akt and mTOR signaling pathways.
- Regulation of cell size and number by the translational machinery
Publications
Featured Publications
- PP2A-dependent disruption of centrosome replication and cytoskeleton organization in Drosophila by SV40 small tumor antigen
- S. Kotadia, L.R. Kao, S.A. Comerford, R.T. Jones, R.E. Hammer and T.L. Megraw Oncogene 2008 Epublished 2008 1-13
- Elucidation of a universal size-control mechanism in Drosophila and mammals
- Dong, J., Feldmann, G., Huang, J., Wu, S., Zhang, N., Comerford, S. A., Gayyed, M. F., Anders, R. A., Maitra, A. and D. Pan Cell September 2007 130 (6) 1120-33
- Induction of hepatocyte proliferation and death by modulation of a liver-specific SV40 T-antigen transgene.
- Comerford, S.A., Clouthier, D.E., Hinnant, E. A. and Hammer, R.E. Oncogene 2003 22 2515-2530
- Hepatic fibrosis, glomerulosclerosis, and a lipodystrophy-like syndrome in PEPCK-TGF-beta 1 transgenic mice.
- Comerford, S.A., Clouthier, D.E., and Hammer, R.E. J. Clin. Invest. 1997 100 2697-2713
- E6 and E7 expression from the HPV 18 LCR: development of genital hyperplasia and neoplasia in transgenic mice.
- Comerford, S.A., Maika, S.A., Laimins, L.A., Messing, A., Elsasser, H.P., and Hammer, R.E. Oncogene 1995 10 587-597