Feng Cai, Ph.D. Titles and Appointments Assistant Professor School Medical School Department Children's Medical Center Research Institute at UT Southwestern | Pediatrics Biography Feng Cai, Ph.D., received his B.Sc. in 1999 from Lanzhou University in China. He pursued his Ph.D. in glycochemistry from University of Illinois at Chicago and Wayne State University. In 2009, Dr. Cai moved to Dallas for postdoctoral research in asymmetric catalysis and medicinal chemistry at UT Southwestern in the Department of Biochemistry. He moved back to China in 2015 to resume his interests in glycochemistry and chemical biology. Dr. Cai returned to Dallas to study metabolomics at Children's Medical Center Research Institute at UT Southwestern (CRI) with Ralph DeBerardinis, Ph.D., and joined CRI's Metabolomics Facility. In 2023, Dr. Cai was promoted to a research assistant professor. Education Graduate School University of Illinois at Chic (2007), Chemistry Graduate School Wayne State University (2009), Chemistry Publications Featured Publications Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples. Cai F, Bezwada D, Cai L, Mahar R, Wu Z, Chang MC, Pachnis P, Yang C, Kelekar S, Gu W, Brooks B, Ko B, Vu HS, Mathews TP, Zacharias LG, Martin-Sandoval M, Do D, Oaxaca KC, Jin ES, Margulis V, Malloy CR, Merritt ME, DeBerardinis RJ, Cell Metab 2023 Oct 35 10 1830-1843.e5 The hexosamine biosynthesis pathway is a targetable liability in KRAS/LKB1 mutant lung cancer. Kim J, Lee HM, Cai F, Ko B, Yang C, Lieu EL, Muhammad N, Rhyne S, Li K, Haloul M, Gu W, Faubert B, Kaushik AK, Cai L, Kasiri S, Marriam U, Nham K, Girard L, Wang H, Sun X, Kim J, Minna JD, Unsal-Kacmaz K, DeBerardinis RJ, Nat Metab 2020 Dec 2 12 1401-1412 Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation. Gu Z, Liu Y, Cai F, Patrick M, Zmajkovic J, Cao H, Zhang Y, Tasdogan A, Chen M, Qi L, Liu X, Li K, Lyu J, Dickerson KE, Chen W, Ni M, Merritt ME, Morrison SJ, Skoda RC, DeBerardinis RJ, Xu J, Cancer Discov 2019 Jun On the Rapid Oxidation of Allene-Containing Phosphines Cai F, Thangada ND, Pan E, Ready JM Organometallics 2013 32 19 5619-5622 Chiral allene-containing phosphines in asymmetric catalysis. Cai F, Pu X, Qi X, Lynch V, Radha A, Ready JM J. Am. Chem. Soc. 2011 Nov 133 45 18066-9 Bacillus anthracis o-succinylbenzoyl-CoA synthetase: reaction kinetics and a novel inhibitor mimicking its reaction intermediate. Tian Y, Suk DH, Cai F, Crich D, Mesecar AD, Biochemistry 2008 Nov 47 47 12434-47 Stereocontrolled glycoside and glycosyl ester synthesis. neighboring group participation and hydrogenolysis of 3-(2'-benzyloxyphenyl)-3,3-dimethylpropanoates. Crich D, Cai F, Org Lett 2007 Apr 9 8 1613-5 Results 1-7 of 7 1 Professional Associations/Affiliations Children's Medical Center Research Institute at UT Southwestern
