Emre Turer, M.D., Ph.D. Titles and Appointments Associate Professor School Medical School Department Internal Medicine | Immunology Graduate Programs Cell and Molecular Biology, Immunology You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Emre Turer, M.D., Ph.D., is an Associate Professor at UT Southwestern Medical Center and a member of its Division of Digestive and Liver Diseases. He specializes in inflammatory bowel disease, ulcerative colitis, and Crohn's disease. Originally from Las Vegas, Nevada, Dr. Turer earned his medical degree and doctoral degree in biological sciences at the University of Chicago Pritzker School of Medicine. He completed both his residency in internal medicine and fellowship in digestive and liver diseases at UT Southwestern as part of the Physician-Scientist Training Program. Board certified in internal medicine and gastroenterology, he joined the UT Southwestern faculty in 2015. Dr. Turer’s research is focused on discovering new genes involved in maintaining intestinal homeostasis. He has published numerous academic articles in the area of intestinal inflammation, including articles in Nature Communications and the Proceedings of the National Academy of Sciences. He also serves as a reviewer for several scholarly journals and is a member of the American Gastroenterological Association and the Crohn’s & Colitis Foundation. In 2020, Dr. Turer was named the Lancaster Family Chair of Gastroenterology by UT Southwestern Medical Center. Education Medical School University of Chicago Pritzker School of Medicine (2009) Residency UT Southwestern Medical Center (2011), Internal Medicine Fellowship UT Southwestern Medical Center (2015), Gastroenterology Research Interest Apoptotic and Inflammatory Signaling Glycosylation Goblet Cells Inflammatory Bowel Disease Intestinal Epithelial Cell Biology Mucosal Immunology Publications Featured Publications Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice. Wang KW, Zhan X, McAlpine W, Zhang Z, Choi JH, Shi H, Misawa T, Yue T, Zhang D, Wang Y, Ludwig S, Russell J, Tang M, Li X, Murray AR, Moresco EMY, Turer EE, Beutler B, Proc. Natl. Acad. Sci. U.S.A. 2019 May Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function. McAlpine W, Sun L, Wang KW, Liu A, Jain R, San Miguel M, Wang J, Zhang Z, Hayse B, McAlpine SG, Choi JH, Zhong X, Ludwig S, Russell J, Zhan X, Choi M, Li X, Tang M, Moresco EMY, Beutler B, Turer E Proc. Natl. Acad. Sci. U.S.A. 2018 12 115 49 E11523-E11531 The Rab32-LRMDA-Retriever Complex is a Key Regulator of Intestinal Immune Homeostasis. Song R, Ngoka C, Singla A, Kramer DA, Diwaker A, Boesch DJ, Liu Q, Moresco JJ, Beutler B, Reinecker HC, Burstein E, Chen B, Turer EE, bioRxiv 2025 Jul Structural basis for Retriever-SNX17 assembly and endosomal sorting. Singla A, Boesch DJ, Fung HYJ, Ngoka C, Enriquez AS, Song R, Kramer DA, Han Y, Banarer E, Lemoff A, Juneja P, Billadeau DD, Bai X, Chen Z, Turer EE, Burstein E, Chen B, Nat Commun 2024 Nov 15 1 10193 The dual lipid desaturase/hydroxylase DEGS2 controls phytoceramide levels necessary to counter intestinal inflammation. Song R, Fond A, Li X, Tang M, Zhan X, Gordillo R, Moresco EMY, Beutler B, Turer EE, Dis Model Mech 2023 Sep 16 9 Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation. Song R, McAlpine W, Fond AM, Nair-Gill E, Choi JH, Nyström EEL, Arike L, Field S, Li X, SoRelle JA, Moresco JJ, Moresco EMY, Yates JR, Azadi P, Ni J, Birchenough GMH, Beutler B, Turer EE, Nat Commun 2023 Jun 14 1 3652 Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation. Misawa T, SoRelle JA, Choi JH, Yue T, Wang KW, McAlpine W, Wang J, Liu A, Tabeta K, Turer EE, Evers B, Nair-Gill E, Poddar S, Su L, Ou F, Yu L, Russell J, Ludwig S, Zhan X, Hildebrand S, Li X, Tang M, Murray AR, Moresco EMY, Beutler B, Sci Immunol 2020 Jan 5 43 Research Techniques Made Simple: Forward Genetic Screening to Uncover Genes Involved in Skin Biology. McAlpine W, Russell J, Murray AR, Beutler B, Turer E, J. Invest. Dermatol. 2019 09 139 9 1848-1853.e1 mutation causes hyperphagic obesity, diabetes and hepatic steatosis. Turer EE, San Miguel M, Wang KW, McAlpine W, Ou F, Li X, Tang M, Zang Z, Wang J, Hayse B, Evers B, Zhan X, Russell J, Beutler B Dis Model Mech 2018 12 11 12 The class I myosin MYO1D binds to lipid and protects against colitis. McAlpine W, Wang KW, Choi JH, San Miguel M, McAlpine SG, Russell J, Ludwig S, Li X, Tang M, Zhan X, Choi M, Wang T, Bu CH, Murray AR, Moresco EMY, Turer EE, Beutler B Dis Model Mech 2018 Sep 11 9 Results 1-10 of 23 1 2 3 Next Last Honors & Awards President's Research Council AwardUTSW (2017) Fellow Research AwardCrohn's and Colitis Foundation of America (2014) Keystone Scholar AwardKeystone Symposium (2005) UCLA Merck Index Award for Outstanding Achievement in Undergraduate ChemistryUniversity of California, Los Angeles (2000)
