Rebecca Faulkner, Ph.D. Titles and Appointments Assistant Instructor School Medical School Department Internal Medicine Education Graduate School (2014), Cell Regulation Research Interest Lipid Metabolism Publications Featured Publications Allosteric regulation of UBIAD1 trafficking from ER to Golgi revealed by chemical genetic screening. Jun DJ, Schumacher MM, Jo Y, Faulkner RA, Yang Y, Tsien J, Qin T, DeBose-Boyd RA, Proc Natl Acad Sci U S A 2025 May 122 20 e2426532122 Direct binding to sterols accelerates endoplasmic reticulum-associated degradation of HMG CoA reductase. Faulkner RA, Yang Y, Tsien J, Qin T, DeBose-Boyd RA, Proc Natl Acad Sci U S A 2024 Feb 121 7 e2318822121 Regulated degradation of HMG CoA reductase requires conformational changes in sterol-sensing domain. Chen H, Qi X, Faulkner RA, Schumacher MM, Donnelly LM, DeBose-Boyd RA, Li X, Nat Commun 2022 Jul 13 1 4273 Synthesis, function, and regulation of sterol and nonsterol isoprenoids. Faulkner R, Jo Y, Front Mol Biosci 2022 9 1006822 Retriever is a multiprotein complex for retromer-independent endosomal cargo recycling. McNally KE, Faulkner R, Steinberg F, Gallon M, Ghai R, Pim D, Langton P, Pearson N, Danson CM, Nägele H, Morris LL, Singla A, Overlee BL, Heesom KJ, Sessions R, Banks L, Collins BM, Berger I, Billadeau DD, Burstein E, Cullen PJ, Nat Cell Biol 2017 Oct 19 10 1214-1225 Endosomal sorting of Notch receptors through COMMD9-dependent pathways modulates Notch signaling. Li H, Koo Y, Mao X, Sifuentes-Dominguez L, Morris LL, Jia D, Miyata N, Faulkner RA, van Deursen JM, Vooijs M, Billadeau DD, van de Sluis B, Cleaver O, Burstein E, J Cell Biol 2015 Nov 211 3 605-17 Lipid-regulated degradation of HMG-CoA reductase and Insig-1 through distinct mechanisms in insect cells. Faulkner RA, Nguyen AD, Jo Y, DeBose-Boyd RA, J Lipid Res 2013 Apr 54 4 1011-22 Results 1-7 of 7 1
