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Sherwood Brown, M.D.,  Ph.D.

Sherwood Brown, M.D., Ph.D.

Titles and Appointments

Distinguished Teaching Professor

Professor

Endowed Title
Aradine S. Ard Chair in Brain Science; Lou and Ellen McGinley Distinguished Chair in Psychiatric Research
School
Medical School
Department
Psychiatry
Graduate Programs
Clinical Psychology

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For more information on the doctor and patient care, please visit the clinical profile.

  • Biography

    E. Sherwood Brown, M.D., Ph.D. MBA, is Professor of Psychiatry with Tenure, the Lou and Ellen McGinley Distinguished Chair in Psychiatric Research and Aradine S. Ard Chair in Brain Research, Vice Chair for Clinical Research, Chief of the Division of Clinical Neuroscience, and Director of the Psychoneuroendocrine Research Program at The University of Texas Southwestern Medical Center. He received B.A. and Ph.D. degrees in Chemistry from Texas Christian University. He received an M.D. degree from the University of Texas Medical School at Houston, and completed a psychiatry residency, on the research track, at UT Southwestern Medical Center followed by a research fellowship. He also completed an MBA,with Healthcare Organization Leadership Concentration, at the University of Texas at Dallas. He is board-certified in psychiatry and consultation-liaison psychiatry and is President of the Academy of Consultation-Liaison Psychiatry. 

    He serves on several journal editorial boards including Biological Psychiatry:Cognitive Neuroscience and Neuroimaging  and Journal of Affective Disorders, and is Editor-in-Chief of the Journal of Dual Diagnosis. Dr. Brown’s research focuses on comorbidities of mood disorders including medical illness and substance abuse. He has had numerous grants from NIH and private foundations, including grants from NIAAA and NIDA examining the treatment of patients with bipolar disorder and substance dependence, a grant from NHLBI examining the treatment of depressed asthma patients, NIA exploring neurosteroid treatments for peri-menopausal depression and NIMH examining the effects of stress and corticosteroids on the human brain. He has published well over 200 research papers, books, chapters, reviews and editorials. 

  • Education
    Medical School
    UT Health Science Center McGovern Medical School (1993)
    Internship
    UT Southwestern Medical Center (1994), Psychiatry
    Residency
    UT Southwestern Medical Center (1997), Psychiatry
    Fellowship
    UT Southwestern Medical Center (1998), Research
  • Research Interest
    • Depression in asthma patients
    • Effects of corticosteroids on the hippocampus
    • Treatment of bipolar depression
    • Treatment of patients with bipolar disorder and substance abuse
  • Publications

    Star Featured Publications

    Associations of a Composite Stress Measurement Tool With Cardiovascular Risk Factors and Outcomes: Findings From the Dallas Heart Study.
    Eleazu I, Ayers C, Navar AM, Salhadar K, Albert M, Carnethon M, Brown ES, Ogbu Nwobodo L, Carter S, Bess C, Powell-Wiley TM, de Lemos JA, J Am Heart Assoc 2025 Feb e033752
    The relationship between asthma and suggested alcohol dependence and heavy alcohol use in the Cooper Center longitudinal study: The role of depressive symptom severity.
    Agarwal CD, Shuval K, Li Q, DeFina LF, Barlow CE, Khan DA, Brown ES, J Affect Disord 2024 Nov 370 356-361
    Depressive Symptom Severity in Mid- to Late-Life in Individuals with and without Asthma.
    Palka JM, Peacock M, Tusken M, Ibrahim M, Najjab A, Carter L, Khan DA, Brown ES, J Allergy Clin Immunol Pract 2024 Sep
    IQ in high school as a predictor of midlife alcohol drinking patterns.
    Druffner N, Egan D, Ramamurthy S, O'Brien J, Davis AF, Jack J, Symester D, Thomas K, Palka JM, Thakkar VJ, Brown ES, Alcohol Alcohol 2024 May 59 4
    The relationship between alcohol consumption and amygdala volume in a community-based sample.
    Pho C, Yu FF, Palka JM, Brown ES, Brain Imaging Behav 2024 Apr
    Contribution of caregiver and child anxiety and depressive symptoms to child asthma-related quality of life.
    Gwak DY, Tea JC, Fatima FN, Palka JM, Lehman H, Khan DA, Zhou H, Wood BL, Miller BD, Brown ES, Ann Allergy Asthma Immunol 2024 Mar
    fMRI BOLD responses to film stimuli and their association with exhaled nitric oxide in asthma and health.
    Ritz T, Kroll JL, Khan DA, Yezhuvath US, Aslan S, Pinkham A, Rosenfield D, Brown ES, Psychophysiology 2024 Feb e14513
    Link between depression and bone mineral density in Cooper Center Longitudinal Study: Indirect effects of vitamin D, inflammation, and physical activity.
    Li C, Palka JM, Abdullah N, Adler-Neal A, Banner B, Efseroff B, Jones C, Clark I, Munoz-Puga M, Boswell N, Karlay B, Siddiqui R, Hergert S, Newton S, Narapureddy S, Tran V, Leonard D, DeFina LF, Barlow CE, Brown ES, J Affect Disord 2023 Oct 344 277-283
    Association of serotonin reuptake inhibitors with asthma control.
    Gajewski AJ, Palka JM, Raitt JM, Agarwal CD, Khan DA, Kao CH, Brown ES, Allergy Asthma Proc 2023 Sep 44 5 354-360
    The cross-sectional relationship among omega-3 fatty acid levels, cardiorespiratory fitness, and depressive symptoms from the Cooper Center Longitudinal Study.
    Kulikova A, Palka JM, Van Enkevort EA, DeFina LF, Ly H, Sunderajan P, Willis BL, Barlow CE, Brown ES, J Psychosom Res 2023 May 168 111181
  • Honors & Awards
    • Gerald L. Klerman Award
      Award for clinical research from National Alliance for Research in Schizophrenia and Depression (NARSAD) (2002)
    • Bristol-Myers Squibb Travel Fellowship
      American College of Neuropsychopharmacology (ACNP) Annual Meeting (1999)
    • Lilly Fellowship Travel Award
      Society of Biological Psychiatry Annual Convention (1998)
    • New Investigator Award
      Award from New Clinical Drug Evaluation Unit (NCDEU) (1997)
  • Professional Associations/Affiliations
    • Academy of Consultation-Liaison Psychiatry (2005)
    • American College of Neuropsychopharmacology (2004)
    • American Psychiatric Association (1993)
    • Research Society on Alcoholism (2007)
    • Society of Biological Psychiatry (2000)
    • Texas Medical Association (1993)