Benjamin Greenberg, M.D. Titles and Appointments Vice Chair of Clinical & Translational Research Professor Endowed Title Cain Denius Scholar in Mobility Disorders; Distinguished Teaching Professor School Medical School Department Neurology | Pediatrics You have reached the Academic Profile. For more information on the doctor and patient care, please visit the clinical profile. Biography Joined UT Southwestern: 2009 Clinical Interests: Dr. Greenberg is recognized internationally as an expert in rare autoimmune disorders of the central nervous system (e.g. transverse myelitis, neuromyelitis optica, ADEM, and autoimmune encephalitis). He splits his clinical time between seeing both adult and pediatric patients. He routinely consults on the inpatient units of Clements University Hospital, Parkland, and Children’s. Research: His research interests are in both the diagnosis and treatment of transverse myelitis, neuromyelitis optica, encephalitis, multiple sclerosis, and infections of the nervous system. He is actively involved in developing better ways to diagnose and prognosticate for and treat patients with these disorders. He has led an effort to improve biorepository development and has created uniform protocols for sample handling and analysis. As part of this initiative, his research has identified novel biomarkers that may be able to distinguish between patients with various neurologic disorders. He also coordinates Phase 1, Phase 2, and Phase 3 trials that study new treatments to prevent neurologic damage and restore function to those who have already been affected. Leadership: He currently serves as the Vice Chair for Clinical and Translational Research for the Department of Neurology. When he joined UT Southwestern, he was named Deputy Director of the Multiple Sclerosis Program and Director of the new Transverse Myelitis and Neuromyelitis Optica Program. That same year he established the Pediatric Demyelianting Disease Program at Children’s Medical Center Dallas. Background: Dr. Benjamin Greenberg received his Bachelor of Arts degree from Johns Hopkins University and his Masters Degree in Molecular Microbiology and Immunology from the Johns Hopkins School of Public Health in Baltimore, Maryland. He attended medical school at Baylor College of Medicine in Houston, Texas. Then, he completed an internship in medicine at Rush Presbyterian-St. Lukes Medical Center in Chicago, Illinois before going on to his residency in neurology at The Johns Hopkins Hospital in Baltimore, MD. He then joined the faculty within the Division of Neuroimmunology at Hopkins and became the co-director of the Transverse Myelitis Center and director of the Encephalitis Center. In January of 2009 he was recruited to the faculty at the University of Texas Southwestern Medical Center. Education Medical School Baylor College of Medicine (2001) Internship Rush-Presbyterian-St. Lukes Med Ctr - GME (2002), Internal Medicine Residency Johns Hopkins School of Medicine (2005), Neurology Research Interest Acute Disseminated Encephalomyelitis (ADEM) Acute Flaccid Myelitis anti-MOG Antibody Associated Disease anti-NMDAR Antibody Encephalitis Autoimmune Encephalitis Biomarkers of Disease Clinical Treatment Trials Multiple Sclerosis Neuromyelitis Optica Optic Neuritis Transverse Myelitis Publications Neuronal ceroid lipofuscinoses type 7 (CLN7): a case series reporting cross sectional and retrospective clinical data to evaluate validity of standardized tools to assess disease progression, quality of life, and adaptive skills Kayani S, BordesEdgar V, Lowden A, Nettesheim ER, Dahshi H, Messahel S, Minassian BA, Greenberg BM Orphanet Journal of Rare Diseases 2024 Dec 19 Astrocytic stress response is induced by exposure to astrocyte-binding antibodies expressed by plasmablasts from pediatric patients with acute transverse myelitis Smith C, Telesford KM, Piccirillo SG, Licon-Munoz Y, Zhang W, Tse KM, Rivas JR, Joshi C, Shah DS, Wu AX, Trivedi R, Christley S, Qian Y, Cowell LG, Scheuermann RH, Stowe AM, Nguyen L, Greenberg BM, Monson NL Journal of Neuroinflammation 2024 Dec 21 Correction: Evidence of brain target engagement in Parkinson’s disease and multiple sclerosis by the investigational nanomedicine, CNM- Au8, in the REPAIR phase 2 clinical trials (Journal of Nanobiotechnology, (2023), 21, 1, (478), 10.1186/s12951-023-02236-z) Ren J, Dewey RB, Rynders A, Evan J, Evan J, Ligozio S, Ho KS, Sguigna PV, Glanzman R, Hotchkin MT, Dewey RB, Greenberg BM Journal of Nanobiotechnology 2024 Dec 22 Smouldering-Associated Worsening in Multiple Sclerosis: An International Consensus Statement on Definition, Biology, Clinical Implications, and Future Directions Scalfari A, Traboulsee A, Oh J, Airas L, Bittner S, Calabrese M, Garcia Dominguez JM, Granziera C, Greenberg B, Hellwig K, Illes Z, Lycke J, Popescu V, Bagnato F, Giovannoni G Annals of Neurology 2024 Nov 96 826-845 Development and validation of a claims-based algorithm to identify patients with Neuromyelitis Optica Spectrum disorder Patel AM, Exuzides A, Yermilov I, Dalglish H, Gibbs SN, Reddy SR, Chang E, Paydar C, Broder MS, Cohan S, Greenberg B, Levy M Journal of the Neurological Sciences 2024 Aug 463 Immune-mediated myositis following gene therapy for Duchenne muscular dystrophy: a case report Iannaccone ST, Cai C, Rhem B, Batley K, Rajaram V, Greenberg BM, Dharia S, Zaidman CM Journal of neurology 2024 Aug 271 5659-5664 The positive predictive value of MOG-IgG testing based on the 2023 diagnostic criteria for MOGAD Nguyen L, Singh S, Feltrin FS, Tardo LM, Clarke RL, Wang CX, Greenberg BM Multiple Sclerosis Journal - Experimental, Translational and Clinical 2024 Jul 10 AAV gene therapy for hereditary spastic paraplegia type 50: a phase 1 trial in a single patient Dowling JJ, Pirovolakis T, Devakandan K, Stosic A, Pidsadny M, Nigro E, Sahin M, Ebrahimi-Fakhari D, Messahel S, Varadarajan G, Greenberg BM, Chen X, Minassian BA, Cohn R, Bonnemann CG, Gray SJ Nature medicine 2024 Jul 30 1882-1887 Emerging Cerebrospinal Fluid Biomarkers of Disease Activity and Progression in Multiple Sclerosis Cross AH, Gelfand JM, Thebault S, Bennett JL, Von Büdingen HC, Cameron B, Carruthers R, Edwards K, Fallis R, Gerstein R, Giacomini PS, Greenberg B, Hafler DA, Ionete C, Kaunzner UW, Kodama L, Lock C, Longbrake EE, Musch B, Pardo G, Piehl F, Weber MS, Yuen S, Ziemssen T, Bose G, Freedman MS, Anania VG, Ramesh A, Winger RC, Jia X, Herman A, Harp C, Bar-Or A JAMA neurology 2024 Apr 81 373-383 Clinical analysis of myelin oligodendrocyte glycoprotein antibody-associated disease in a diverse cohort of children: A single-center observational study Nguyen L, Wang CX, Hernandez RS, Greenberg BM Multiple Sclerosis and Related Disorders 2024 Apr 84 Results 1-10 of 236 1 2 3 4 5 Next Last Books Featured Books Myelopathy: A Guide to Diagnosis and Treatment Benjamin Greenberg (Ed.) (2022). Honors & Awards D Magazine Best Doctors in Dallas (2023) D Magazine Best Doctors in Dallas (2022) UT Southwestern Medical School Teaching Award (2022) D Magazine Best Doctors in Dallas (2021) UT Southwestern Medical School Teaching Award (2021) D Magazine Best Doctors in Dallas (2020) UT Southwestern Medical School Teaching Award (2020) D Magazine Best Doctors in Dallas (2019) UT Southwestern Medical School Teaching Award (2019) D Magazine Best Doctors in Medicine (2018) UT Southwestern Medical School Teaching Award (2018) D Magazine Best Doctors in Dallas (2017) UT Southwestern Medical School Teaching Award (2017) D Magazine Best Doctors in Dallas (2016) University of Texas Southwestern Academy of Teachers (2016) UT Southwestern Medical School Teaching Award (2016) University of Texas Board of Regents Teaching Award (2015) UT Southwestern Medical School Teaching Award (2015) UT Southwestern Medical School Teaching Award (2014) UT Southwestern Medical School Teaching Award (2013) UT Southwestern Medical School Teaching Award (2012) Fred Baskin Investigator AwardResearch Award (2011) UT Southwestern Medical School Teaching Award (2011) UT Southwestern Medical School Teaching Award (2010) UT Southwestern Neurology Trephined Cranium Teaching Award (2010) Accelerated Cure Project Physician of Distinction Award (2009) UT Southwestern Medical School Teaching Award (2009) Frank FordDepart of Neurology Teaching Award (2008) Guy McKhannResident Teaching Award (2005) Service Award From MarylandMultiple Sclerosis Society (2004) Intern of the Year AwardRush Internal Medicine (2002) Alpha Omega Alpha Honor Society, Baylor College of Medicine (2001) Professional Associations/Affiliations American Academy of Neurology (2002) American Neurological Association (2014) International Society for Biological and Environmental Repositories (2009) Siegel Rare Neuroimmune Association (2004)
