Dr. Benjamin Greenberg received his Bachelor of Arts degree from Johns Hopkins University and his Masters Degree in Molecular Microbiology and Immunology from the Johns Hopkins School of Public Health in Baltimore, Maryland. He attended medical school at Baylor College of Medicine in Houston, Texas. Then, he completed an internship in medicine at Rush Presbyterian-St. Lukes Medical Center in Chicago, Illinois before going on to his residency in neurology at The Johns Hopkins Hospital in Baltimore, MD. He then joined the faculty within the division of neuroimmunology at Hopkins and became the co-director of the Transverse Myelitis Center and director of the Encephalitis Center. In January of 2009 he was recruited to the faculty at the University of Texas Southwestern Medical Center where he was named Deputy Director of the Multiple Sclerosis Program and Director of the new Transverse Myelitis and Neuromyelitis Optica Program. That same year he established the Pediatric Demyelianting Disease Program at Children’s Medical Center Dallas.

Dr. Greenberg is recognized internationally as an expert in rare autoimmune disorders of the central nervous system (e.g. transverse myelitis, neuromyelitis optica, ADEM and autoimmune encephalitis). He splits his clinical time between seeing both adult and pediatric patients. He routinely consults on the inpatient units of University Hospital, Zale Lipshy, Parkland and Children’s. His research interests are in both the diagnosis and treatment of transverse myelitis, neuromyelitis optica, encephalitis, multiples sclerosis and infections of the nervous system. He is actively involved in developing better ways to diagnose and prognosticate for patients with these disorders. He has led an effort to improve biorepository development and has created uniform protocols for sample handling and analysis. As part of this initiative his research has identified novel biomarkers that may be able to distinguish between patients with various neurologic disorders. He also coordinates trials that study new treatments to prevent neurologic damage and restore function to those who have already been affected. He currently serves as the Director of the Perot Foundation Neurosciences Translational Reseach Center and is a Cain Denius Foundation Scholar in Mobiity Disorders.


Medical School
Baylor College of Medicine (2001)
Rush-Presbyterian-St. Lukes Med Ctr - GME (2002), Internal Medicine
Johns Hopkins School of Medicine (2005), Neurology

Research Interest

  • Acute Disseminated Encephalomyelitis (ADEM)
  • Acute Flaccid Myelitis
  • anti-MOG Antibody Associated Disease
  • anti-NMDAR Antibody Encephalitis
  • Autoimmune Encephalitis
  • Biomarkers of Disease
  • Clinical Treatment Trials
  • Multiple Sclerosis
  • Neuromyelitis Optica
  • Optic Neuritis
  • Transverse Myelitis


Featured Publications LegendFeatured Publications

Increased Prevalence of Familial Autoimmune Disease in Children With Opsoclonus-Myoclonus Syndrome.
Santoro JD, Kerr LM, Codden R, Casper TC, Greenberg BM, Waubant E, Kong SW, Mandl KD, Gorman MP, Neurol Neuroimmunol Neuroinflamm 2021 Nov 8 6
Familial History of Autoimmune Disorders Among Patients With Pediatric Multiple Sclerosis.
Greenberg BM, Casper TC, Mar SS, Ness JM, Plumb P, Liang S, Goyal M, Weinstock-Guttman B, Rodriguez M, Aaen GS, Belman A, Barcellos LF, Rose JW, Gorman MP, Benson LA, Candee M, Chitnis T, Harris YC, Kahn IL, Roalstad S, Hart J, Lotze TE, Rensel M, Rubin JP, Schreiner TL, Tillema JM, Waldman AT, Krupp L, Graves J, Drake K, Waubant E, Neurol Neuroimmunol Neuroinflamm 2021 09 8 5
Molecular Level Characterization of Circulating Aquaporin-4 Antibodies in Neuromyelitis Optica Spectrum Disorder.
Li J, Bazzi SA, Schmitz F, Tanno H, McDaniel JR, Lee CH, Joshi C, Kim JE, Monson N, Greenberg BM, Hedfalk K, Melamed E, Ippolito GC, Neurol Neuroimmunol Neuroinflamm 2021 Jul 8 5
In Depth Evaluation of a Case of Presumed Myocarditis Following the Second Dose of COVID-19 mRNA Vaccine.
Muthukumar A, Narasimhan M, Li QZ, Mahimainathan L, Hitto I, Fuda F, Batra K, Jiang X, Zhu C, Schoggins J, Cutrell JB, Croft CL, Khera A, Drazner MH, Grodin JL, Greenberg BM, Mammen PPA, Morrison SJ, de Lemos JA, Circulation 2021 Jun
Acute flaccid myelitis: long-term outcomes recorded in the CAPTURE study compared with paediatric transverse myelitis.
Greenberg B, Plumb P, Cutter G, Dean J, Desena A, Hopkins S, Krishnan C, Pardo C, Recio A, Schreiner T, Yeh EA, McCreary M, BMJ Neurol Open 2021 3 1 e000127
Acute flaccid myelitis: cause, diagnosis, and management.
Murphy OC, Messacar K, Benson L, Bove R, Carpenter JL, Crawford T, Dean J, DeBiasi R, Desai J, Elrick MJ, Farias-Moeller R, Gombolay GY, Greenberg B, Harmelink M, Hong S, Hopkins SE, Oleszek J, Otten C, Sadowsky CL, Schreiner TL, Thakur KT, Van Haren K, Carballo CM, Chong PF, Fall A, Gowda VK, Helfferich J, Kira R, Lim M, Lopez EL, Wells EM, Yeh EA, Pardo CA, Lancet 2020 Dec
Selective Depletion of Antigen-Specific Antibodies for the Treatment of Demyelinating Disease.
Sun W, Khare P, Wang X, Challa DK, Greenberg BM, Ober RJ, Ward ES, Mol Ther 2020 Nov
Utilization of Visual Acuity Retroilluminated Charts for the Assessment of Afferent Visual System Dysfunction in a Pediatric Neuroimmunology Population.
Sguigna PV, McCreary MC, Conger DL, Graves JS, Benson LA, Waldman AT, Greenberg BM, J Neuroophthalmol 2020 Aug
Trial of Satralizumab in Neuromyelitis Optica Spectrum Disorder.
Yamamura T, Kleiter I, Fujihara K, Palace J, Greenberg B, Zakrzewska-Pniewska B, Patti F, Tsai CP, Saiz A, Yamazaki H, Kawata Y, Wright P, De Seze J, N. Engl. J. Med. 2019 Nov 381 22 2114-2124
Two cases of aquaporin-4 positive neuromyelitis optica associated with T-cell lymphoma.
Blackburn K, Wang C, Greenberg B, J. Neuroimmunol. 2019 Oct 338 577092

Honors & Awards

  • D Magazine Best Doctors in Dallas
  • D Magazine Best Doctors in Dallas
  • D Magazine Best Doctors in Dallas
  • UT Southwestern Medical School Teaching Award
  • D Magazine Best Doctors in Medicine
  • UT Southwestern Medical School Teaching Award
  • D Magazine Best Doctors in Dallas
  • UT Southwestern Medical School Teaching Award
  • D Magazine Best Doctors in Dallas
  • University of Texas Southwestern Academy of Teachers
  • UT Southwestern Medical School Teaching Award
  • University of Texas Board of Regents Teaching Award
  • UT Southwestern Medical School Teaching Award
  • UT Southwestern Medical School Teaching Award
  • UT Southwestern Medical School Teaching Award
  • UT Southwestern Medical School Teaching Award
  • Fred Baskin Investigator Award
    Research Award (2011)
  • UT Southwestern Medical School Teaching Award
  • UT Southwestern Medical School Teaching Award
  • UT Southwestern Neurology Trephined Cranium Teaching Award
  • Accelerated Cure Project Physician of Distinction Award
  • UT Southwestern Medical School Teaching Award
  • Frank Ford
    Depart of Neurology Teaching Award (2008)
  • Guy McKhann
    Resident Teaching Award (2005)
  • Service Award From Maryland
    Multiple Sclerosis Society (2004)
  • Intern of the Year Award
    Rush Internal Medicine (2002)
  • Alpha Omega Alpha Honor Society, Baylor College of Medicine

Professional Associations/Affiliations

  • American Neurological Association (2014)
  • International Society for Biological and Environmental Repositories (2009)
  • Siegel Rare Neuroimmune Association (2004)
  • American Academy of Neurology (2002)