Fangyu Peng, M.D., is a Professor of Radiology at UT Southwestern Medical Center and a member of its Nuclear Medicine Division. He also holds a secondary appointment in the Advanced Imaging Research Center. His clinical interests include general nuclear medicine, PET imaging, and computed tomography (CT), with a particular interest in oncology and neurology. 

Dr. Peng earned his medical degree at Jiangxi Medical College in Nanchang, China. He then earned a master’s degree in molecular virology at Chinese Academy of Preventive Medicine's Institute of Virology in Beijing. He earned a doctoral degree in microbiology and immunology at the University of South Florida College of Medicine in Tampa. He then completed a research fellowship program in hematopathology at Ball Memorial Hospital in Muncie, Indiana, before completing his residency in pathology at Upstate Medical University in Syracuse, New York. Dr. Peng then completed a residency in nuclear medicine at the University of Connecticut Health Center in Farmington, and in anatomic pathology at Hartford Hospital. He completed his formal training with a fellowship program in nuclear medicine and molecular imaging at the National Institutes of Health in Bethesda, Maryland.

Before being recruited in 2008 to Nuclear Medicine Division, Dr. Peng served as an Assistant Professor of Radiology and Pediatrics at Wayne State University School of Medicine in Detroit, Michigan.

At UT Southwestern, he troubleshoots and improves imaging protocols, and actively participates in educational endeavors, in addition to his regular clinical responsibilities.

Dr. Peng focuses his research on inherited and acquired copper metabolism disorders in Wilson’s disease, Alzheimer’s disease, and traumatic brain injury, and investigates molecular imaging and targeted radionuclide cancer therapy with copper radionuclides. His research has been published in more than 50 peer-reviewed publications. He also invented and received a patent for intracellular trapping of radionuclides by enzyme-mediated reduction.


Medical School
Jiangxi Medical College (1982)
Other Post Graduate Training
University of South Florida (1994)
Graduate School
University of South Florida (1994), Medical Microbiology & Immunology
Ball Memorial Hospital (1996), Hematopathology
SUNY Upstate Medical University (1998), Pathology
University of Connecticut Health Center (2000), Nuclear Medicine
Hartford Hospital (2002), Anatomic Pathology
Warren Grant Magnuson Clinical Center - NIH (2003), Nuclear Medicine

Research Interest

  • Molecular imaging and targeted radionuclide cancer therapy with copper radionuclides
  • Positron Emission Tomography of altered copper fluxes in Wilson's disease, Alzheimer's disease, and traumatic brain injury with copper-64 chloride


Featured Publications LegendFeatured Publications

Recent Advances in Cancer Imaging with 64CuCl2 PET/CT.
Peng F, Nucl Med Mol Imaging 2022 Apr 56 2 80-85
Reduction in Copper Uptake and Inhibition of Prostate Cancer Cell Proliferation by Novel Steroid-based Compounds.
Xie F, Peng F, Anticancer Res 2021 Dec 41 12 5953-5958
Alteration of Copper Fluxes in Brain Aging: A Longitudinal Study in Rodent Using 64CuCl2-PET/CT.
Peng F, Xie F, Muzik O Aging Dis 2018 Feb 9 1 109-118
Radiopharmaceuticals for Assessment of Altered Metabolism and Biometal Fluxes in Brain Aging and Alzheimer's Disease with Positron Emission Tomography.
Xie F, Peng F J. Alzheimers Dis. 2017 Jun

Honors & Awards

  • Fellow
    American College of Nuclear Medicine (2019)
  • Chief Resident in Nuclear Medicine
    University of Connecticut Health Center (1999-2000)

Professional Associations/Affiliations

  • American Board of Nuclear Medicine (2001)
  • American College of Nuclear Medicine (2014)
  • International Society to Advance Alzheimer’s Research and Treatment (2016)
  • Society of Nuclear Medicine and Molecular Imaging (1998)