Education

Undergraduate
National Taiwan University (2000), Medical Technology
Graduate School
National Taiwan University (2007), Biochemistry

Publications

Featured Publications LegendFeatured Publications

CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells.
Kim J, Hu Z, Cai L, Li K, Choi E, Faubert B, Bezwada D, Rodriguez-Canales J, Villalobos P, Lin YF, Ni M, Huffman KE, Girard L, Byers LA, Unsal-Kacmaz K, Peña CG, Heymach JV, Wauters E, Vansteenkiste J, Castrillon DH, Chen BPC, Wistuba I, Lambrechts D, Xu J, Minna JD, DeBerardinis RJ Nature 2017 Jun 546 7656 168-172
Three-dimensional spheroid culture targeting versatile tissue bioassays using a PDMS-based hanging drop array.
Kuo CT, Wang JY, Lin YF, Wo AM, Chen BPC, Lee H Sci Rep 2017 Jun 7 1 4363
Coordination of the Ser2056 and Thr2609 Clusters of DNA-PKcs in Regulating Gamma Rays and Extremely Low Fluencies of Alpha-Particle Irradiation to G0/G1 Phase Cells.
Nagasawa H, Lin YF, Kato TA, Brogan JR, Shih HY, Kurimasa A, Bedford JS, Chen BP, Little JB Radiat. Res. 2017 Jan
FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress.
Yang Y, Liu Z, Wang F, Temviriyanukul P, Ma X, Tu Y, Lv L, Lin YF, Huang M, Zhang T, Pei H, Chen BP, Jansen JG, de Wind N, Fischhaber PL, Friedberg EC, Tang TS, Guo C Nucleic Acids Res. 2015 Jul
DNA-PKcs phosphorylates hnRNP-A1 to facilitate the RPA-to-POT1 switch and telomere capping after replication.
Sui J, Lin YF, Xu K, Lee KJ, Wang D, Chen BP Nucleic Acids Res. 2015 May
The Catalytic Subunit of DNA-Dependent Protein Kinase Coordinates with Polo-Like Kinase 1 to Facilitate Mitotic Entry.
Lee KJ, Shang ZF, Lin YF, Sun J, Morotomi-Yano K, Saha D, Chen BP Neoplasia 2015 Apr 17 4 329-38
NSCLC cells demonstrate differential mode of cell death in response to the combined treatment of radiation and a DNA-PKcs inhibitor.
Yu L, Shang ZF, Hsu FM, Zhang Z, Tumati V, Lin YF, Chen BP, Saha D Oncotarget 2015 Jan
Transcriptional elongation requires DNA break-induced signalling.
Bunch H, Lawney BP, Lin YF, Asaithamby A, Murshid A, Wang YE, Chen BP, Calderwood SK Nat Commun 2015 6 10191