Research Interest

  • CRISPR/Cas9 Screening
  • Host-Pathogen Interactions
  • Immunology
  • Norovirus
  • Virology


Featured Publications LegendFeatured Publications

UFMylation inhibits the proinflammatory capacity of interferon-?-activated macrophages.
Balce DR, Wang YT, McAllaster MR, Dunlap BF, Orvedahl A, Hykes BL, Droit L, Handley SA, Wilen CB, Doench JG, Orchard RC, Stallings CL, Virgin HW, Proc Natl Acad Sci U S A 2021 Jan 118 1
CD300lf conditional knockout mouse reveals strain-specific cellular tropism for murine norovirus.
Graziano VR, Alfajaro MM, Schmitz CO, Filler RB, Strine MS, Wei J, Hsieh LL, Baldridge MT, Nice TJ, Lee S, Orchard RC, Wilen CB, J Virol 2020 Nov
Cytidine monophosphate N-acetylneuraminic acid synthetase and solute carrier family 35 member A1 are required for reovirus binding and infection.
Urbanek K, Sutherland DM, Orchard RC, Wilen CB, Knowlton JJ, Aravamudhan P, Taylor GM, Virgin HW, Dermody TS, J Virol 2020 Oct

Professional Associations/Affiliations

  • Washington University School of Medicine (2013-2018)
  • UT Southwestern Medical Center (2008-2013)