Stephen F Austin State Uni (1997), Biology
Graduate School
Stephen F Austin State Uni (1999), Biochemistry
Medical School
Univ of Tx Health Science Ctr (2004), Medicine

Research Interest

  • Diseases of the esophagus
  • Eosinophilic conditions in the GI tract
  • Inflammatory bowel diseases
  • Molecular diagnostics
  • Patient engagement


Featured Publications LegendFeatured Publications

Itraconazole Exerts its Anti-Tumor Effect in Esophageal Cancer by Suppressing the HER2/AKT Signaling Pathway.
Zhang W, Bhagwath AS, Ramzan Z, Williams TA, Subramaniyan I, Edpuganti V, Kallem RR, Dunbar KB, Ding P, Gong K, Geurkink SA, Beg MS, Kim J, Zhang Q, Habib AA, Choi SH, Lapsiwala R, Bhagwath G, Dowell JE, Melton SD, Jie C, Putnam WC, Pham TH, Wang DH, Mol Cancer Ther 2021 Aug
Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation.
Miyata N, Morris LL, Chen Q, Thorne C, Singla A, Zhu W, Winter M, Melton SD, Li H, Sifuentes-Dominguez L, Llano E, Huff-Hardy K, Starokadomskyy P, Lopez A, Reese TA, Turer E, Billadeau DD, Winter SE, Burstein E Cell Rep 2018 Aug 24 9 2342-2355
Laparoscopic ischemic conditioning of the stomach increases neovascularization of the gastric conduit in patients undergoing esophagectomy for cancer.
Pham TH, Melton SD, McLaren PJ, Mokdad AA, Huerta S, Wang DH, Perry KA, Hardaker HL, Dolan JP J Surg Oncol 2017 May
Clinical Implications of Histologic Abnormalities in Ileocolonic Biopsies of Patients With Crohn's Disease in Remission.
Brennan GT, Melton SD, Spechler SJ, Feagins LA J. Clin. Gastroenterol. 2016 Feb
Autocrine VEGF Signaling Promotes Proliferation of Neoplastic Barrett's Epithelial Cells Through a PLC-Dependent Pathway.
Zhang Q, Yu C, Peng S, Xu H, Wright E, Zhang X, Huo X, Cheng E, Pham TH, Asanuma K, Hatanpaa KJ, Rezai D, Wang DH, Sarode V, Melton S, Genta RM, Spechler SJ, Souza RF Gastroenterology 2013 Oct
Clinical implications of histologic abnormalities in colonic biopsy specimens from patients with ulcerative colitis in clinical remission.
Feagins LA, Melton SD, Iqbal R, Dunbar KB, Spechler SJ Inflamm. Bowel Dis. 2013 Jun 19 7 1477-82

Honors & Awards

  • McGovern (UT Houston) Medical School
    Distinguished Alumnus Award (2023)
  • McGovern (UT Houston) Medical School Alumni Association
    President (2016)
  • Leadership Emerging in Academic Departments (LEAD) Program Graduate
    The LEAD Program is designed for junior faculty who aspire to develop their leadership skills. Curriculum includes modules in self-discovery, communication, influence, negotiation, difficult conversations, inspiring trust, and embracing diversity. (2014)
  • North Texas Society of Pathology
    President (2013)
  • ACG Presidential Poster Award
    American College of Gastroenterology Annual Scientific Meeting, San Antonio, TX. (2010)
  • First Place, Poster Competition
    25th Annual John R. Rainey, MD, Residents'/Fellows' Seminar. 89th Annual Meeting for the Texas Society of Pathologists, Galveston, TX (2010)
  • GIPS Abstract Award
    Rodger C. Haggitt Gastrointestinal Pathology Society, 99th Annual Meeting for the United States and Canadian Academy of Pathology, Washington, DC. (2010)

Professional Associations/Affiliations

  • Association for Molecular Pathology - Awards Committee (2022)
  • Association for Molecular Pathology - Chair, Membership Affairs Committee (2020-2022)
  • Association for Molecular Pathology - Chair, Patient Engagement Subcommittee (2018-2020)
  • Association for Molecular Pathology - Nominating Committee, Solid Tumor Subdivision Representative (2017-2019)
  • Association for Molecular Pathology - Professional Relations Committee (2008-2018)
  • VA North Texas Health Care System (2010)
  • VA North Texas Health Care System - Chair, IRB (2016-2022)