Shwu-Yuan Wu, Ph.D.

Assistant Professor

Department: Simmons Comprehensive Cancer Center, Biochemistry

Education

Graduate School Yang-Ming Medical College - China (1986), Biochemistry
Graduate School University of Rochester (1993), Biochemistry

Research Interests

  • Chromatin and Epigenetics
  • Human Papillomaviruses
  • p53 Tumor Supressor Protein
  • Post-Translational Modifications
  • Transcription and Gene Regulation

Publications

Featured Publications Legend

Featured Publications

The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation

Wu, S.-Y. and C.-M. Chiang J. Biol. Chem. 2007 282 13141-13145

CTCF interacts with and recruits the largest subunit of RNA polymerase II to CTCF target sites genome-wide

Chernukhin, I., S. Shamsuddin, S.Y. Kang, R. Bergstrom, Y.-W. Kwon, W. Yu, J. Whitehead, R. Mukhopadhyay, F. Docquier, D. Farrar, I. Morrison, M. Vigneron, S.-Y. Wu, C.-M. Chiang, D. Loukinov, V. Lobanenkov, and E. Klenova Mol. Cell. Biol. 2007 27 1631-1648

Recruitment of TFIIH to the HIV LTR is a rate-limiting step in the emergency of HIV from latency

Kim, Y.K., C.F. Bourgeois, R. Pearson, M. Tyagi, M.J. West, J. Wong, S.-Y. Wu, C.-M. Chiang, and J. Karn EMBO J. 2006 25 3596-3604

Dynamic localization of the human papillomavirus type 11 origin binding protein E2 through mitosis while in association with the spindle apparatus

Dao, L.D., A. Duffy, B.A. Van Tine, S.-Y. Wu, C.-M. Chiang, T.R. Broker, and L.T. Chow J. Virol. 2006 80 4792-4800

SREBP-1c and Sp1 interact to regulate transcription of the gene for phosphoenolpyruvate carboxykinase (GTP) in the liver

Chakravarty, K., S.-Y. Wu, C.-M. Chiang, D. Samols, and R.W. Hanson J. Biol. Chem. 2004 279 15385-15395

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Honors/Awards

  • Postdoctoral Fellow
    Aaron Diamond Foundation (1995)
  • Elon Huntington Hooker Graduate Fellowship
    University of Rochester (1993)