Dr. Huang received his Bachelor’s degree from Tsinghua University in China in 1996. He then obtained a Master’s degree in Peking University in 1999. He received his PhD degree at Biomedical Engineering of Johns Hopkins University School of Medicine in 2005. Immediately after his PhD, he became a Research Associate faculty also at Johns Hopkins School of Medicine in 2005. He went to University of Texas Southwestern Medical Center as an Assistant Professor two years later.

Dr. Huang’s research is focused on developing novel MR techniques to answer fundamental questions on brain development and identify early biomarkers of mental and neurological disorders. In addition, Dr. Huang has extensive experience on signal modeling and tractography with advanced diffusion MRI techniques such as high b, high angular resolution and multi-shell diffusion imaging. His lab has been leading on early structural and connectivity development of human brain with diffusion tensor imaging (DTI). Dr. Huang’s lab has also been one of the first introducing tract analysis with diffusion MRI and tractography for white matter biomarker detection of Alzheimer’s disease, major depression disorder and maltreatment.


Undergraduate Tsinghua University - China , Civil Engineering
Graduate School Peking University - China (1999)
Graduate School Johns Hopkins University (2005), Biomedical Engineering

Research Interest

  • Anatomical MRI
  • Developmental Brain Connectivity and Network
  • Diffusion MRI
  • Identification of clinical biomarkers with DTI
  • MR physics and pulse programming


Featured Publications LegendFeatured Publications

Regional changes of cortical mean diffusivities with aging after correction of partial volume effects.
Jeon T, Mishra V, Uh J, Weiner M, Hatanpaa KJ, White CL, Zhao YD, Lu H, Diaz-Arrastia R, Huang H Neuroimage 2012 Sep 62 3 1705-16
White matter changes in healthy adolescents at familial risk for unipolar depression: a diffusion tensor imaging study.
Huang H, Fan X, Williamson DE, Rao U Neuropsychopharmacology 2011 Feb 36 3
Quantitative cortical mapping of fractional anisotropy in developing rat brains.
Huang H, Yamamoto A, Hossain MA, Younes L, Mori S J. Neurosci. 2008 Feb 28 6
Analysis of noise effects on DTI-based tractography using the brute-force and multi-ROI approach.
Huang H, Zhang J, van Zijl PC, Mori S Magn Reson Med 2004 Sep 52 3

Honors & Awards

  • Sigma Xi
  • Best Thesis Award

Professional Associations/Affiliations

  • IEEE
  • SfN