Margaret Schwarz, M.D.

Medical School	University of Missouri - Kansas City School of Medicine (1987)
Internship	Children's Hospital - Columbus (1988), Pediatrics
Residency	Children's Hospital - Columbus (1990), Pediatrics
Fellowship	Children's Hospital of Pittsburgh (1993), Pediatric Critical Care Medicine

• Critical Care Medicine
• Pediatrics

• Primary Interests
• Cardiac Intensive Care

• angiogenesis
• extracellular matrix
• pancreatic cancer
• pulmonary development
• vasculature

Featured Publications

Emerging Pulmonary Vasculature Lacks Fate Specification.

Schwarz, MA, Caldwell, L., Cafasso, D., and Zheng, H Am J Physiol Lung Cell Mol Physiol. January 2009 296(1): L71-81

Epithelial-mesenchymal interactions are linked to neovascularization.

Schwarz, MA, Wan, ZS, Lui, J. and Lee, MK Am J Respir Cell Mol Biol. June 2004 30(6): 784-92

Endothelial-Monocyte Activating Polypeptide (EMAP) II, a novel antitumor cytokine that suppresses primary and metastatic tumor growth, and induces apoptosis in growing endothelial cells.

Schwarz MA, Kandel, J., Brett, G., Li, J., Hayward, J., Schwarz, RE, Chappey, O., Wautier, J., Chabot, J., Lo Gerfo, P., and Stern, D.; J. Exp. Med. 1999 190(3): 341-354

Metallothionein protects against the cytotoxic and DNA-damaging effects of nitric oxide.

Schwarz, M.A., Lazo, J.S., Yalowich, J.C., Allen, W.P., Whitmore, M., Bergonia, H., Tzeng, E., Billiar, T., Robbins, P., Lancaster, J.R., and Pitt, B.R Pro. Nat. Acad. Sci. 1995 vol. 92 4452-4456

Cytoplasmic metallothionein overexpression protects NIH3T3 cells from tert-Butyl Hydroperoxide toxicity.

Schwarz, M., Lazo, J.S. Yalowich, J., Reynolds, I., Kagan, V., Tyurin, V., Kim, Y-M., Watkins, S., and Pitt, B. J. Biol. Chem. 1994 269(21): 15238-43

Anti-tumor Effects of EMAP II against Pancreatic Cancer through inhibition of Fibronectin-Dependent Proliferation.

Schwarz, RE, Conduri, S., Awasthi, N., Caldwell, L., Cafasso, D., and Schwarz, MA Cancer Biol Ther. April 2010 20;9(8) 1-8

Lung Self-Assembly is Modulated by Tissue Surface Tensions

Schwarz, MA, Zheng, H., Legan, S., and Foty, RA Am J Resp Mol Biol. 2010 epub

Schwarz, MA, Zheng, H., Legan, S., and Foty, RA, Lung Self-Assembly is Modulated by Tissue Surface Tensions

Schwarz, MA, Zheng, H., Legan, S., and Foty, RA Am J Resp Mol Biol. 2010 epub

Emerging Pulmonary Vasculature Lacks Fate Specification.

Schwarz, MA, Caldwell, L., Cafasso, D., and Zheng, H Am J Physiol Lung Cell Mol Physiol. January 2009 296(1) L71-81

Endothelial Monocyte Activating Polypeptide II interferes with VEGF induced angiogenesis signaling.

Awasthti, N., Schwarz, MA, Varma, V., Cappiello, C., and Schwarz, RE Lab Invest. January 2009 89(1) 38-46

• Member, NIH NHLBI RIBT Study Section
  (2005)
• AOA
  (2003)
• Dr. Edward Livingston Trudeau Scholar from the American Lung Association
  (1998)
• AHA Clinician Scientst Award
  (1992)