Biography

Dr. Deshpande completed her medical training as an Infectious Diseases fellow at UT Southwestern in 2009, during which she developed the hollow fiber model for disseminated intracellular Mycobcterium avium intracellulare complex (MAC) infection. Dr. Deshpande practiced as a general infectious diseases physician in the DFW area for four years. She has returned to Dr. Tawanda Gumbo’s lab at UT Southwestern to further pursue interests in pharmacokinetics and pharmacodynamics and optimization of medical therapy for tuberculosis and MAC. She also looks forward to being a part of the clinical general Infectious Diseases services at William P. Clements Jr. University Hospital.

Research Interest

  • Mycobacterium tuberculosis, Mycobacterium avium intracellulare complex
  • Pharmacokinetics/pharmacodynamics of antitubercular and MAC therapy
  • The Hollow Fiber System Model

Publications

Featured Publications LegendFeatured Publications

The antibiotic resistance arrow of time: efflux pump induction is a general first step in the evolution of mycobacterial drug resistance.
Schmalstieg AM, Srivastava S, Belkaya S, Deshpande D, Meek C, Leff R, van Oers NS, Gumbo T Antimicrob. Agents Chemother. 2012 Sep 56 9 4806-15
Pharmacokinetic/pharmacodynamic-based treatment of disseminated Mycobacterium avium.
Deshpande D, Gumbo T Future Microbiol 2011 Apr 6 4 433-9
Moxifloxacin pharmacokinetics/pharmacodynamics and optimal dose and susceptibility breakpoint identification for treatment of disseminated Mycobacterium avium infection.
Deshpande D, Srivastava S, Meek C, Leff R, Hall GS, Gumbo T Antimicrob. Agents Chemother. 2010 Jun 54 6 2534-9
Ethambutol optimal clinical dose and susceptibility breakpoint identification by use of a novel pharmacokinetic-pharmacodynamic model of disseminated intracellular Mycobacterium avium.
Deshpande D, Srivastava S, Meek C, Leff R, Gumbo T Antimicrob. Agents Chemother. 2010 May 54 5 1728-33