Kim Yancey, M.D.

Dr. Kim B. Yancey is Professor and Chair of the Department of Dermatology at the University of Texas Southwestern Medical Center in Dallas. He graduated from the University of Georgia (Summa Cum Laude and Valedictorian), and earned his Medical Degree (Alpha Omega Alpha) from the Medical College of Georgia. Dr. Yancey performed residency training at the Medical College of Georgia and subsequently completed a postdoctoral fellowship in immunodermatology in the Dermatology Branch of the National Cancer Institute at the National Institutes of Health. Dr. Yancey is certified by the American Board of Dermatology, and, in addition, holds special competence in dermatologic immunology and diagnostic laboratory immunology. In 1985, Dr. Yancey joined the faculty of the Uniformed Services University of Health Sciences in Bethesda, Maryland as an Assistant Professor of Dermatology. In 1987, he was promoted to Associate Professor; from 1990-1993 he served as Acting Chairman of this department. In 1993, Dr. Yancey joined the Dermatology Branch of National Cancer Institute as a tenured Senior Investigator at the National Institutes of Health (NIH). His NIH laboratory focused on mechanisms of keratinocyte adhesion to epidermal basement membrane and the pathophysiologic basis of autoimmune and inherited blistering diseases. Between 2001 and 2006, Dr. Yancey served as Professor and Chair of the Department of Dermatology at the Medical College of Wisconsin (MCW). His time was spread among clinical, teaching, research, and administrative responsibilities at MCW, Froedtert Hospital, and the Zablocki Veterans Affairs Medical Center. He was an active member of the Executive Committee of Medical College Physicians between 2004 and 2006, and served as Chair of this body between 2004 and 2005. In 2007, Dr. Yancey was appointed Professor and Chair of the Department of Dermatology at the University of Texas Southwestern Medical Center in Dallas. His professional efforts include clinical care, immunopathology, education, and departmental administrative activities. Dr. Yancey is a member of the American Society for Clinical Investigation, the Society for Investigative Dermatology, the American Academy of Dermatology, the Dermatology Foundation, the American Dermatological Association, and numerous other professional organizations. He is a former Director and Vice President of the American Board of Dermatology, a former member of the Board of Directors, Executive Committee, and President of the Society for Investigative Dermatology, a former member of the Executive Committee and President of the Dermatology Foundation, and current member of numerous editorial boards. In 2007, he received the American Academy of Dermatology’s Marion Sulzberger Award. He has published numerous research manuscripts, monographs, and chapters, served on an array of grant review panels, and presented over 100 scientific abstracts and invited lectures in the U.S. and abroad. He has held research support from the National Institutes of Health for over twenty years.

Medical School

Medical College of Georgia/Georgia Regents University (1978)

Internship

Medical College of Georgia (1979), Internal Medicine

Residency

Medical College of Georgia (1981), Dermatology

Other Post Graduate Training

National Institutes of Health (1982)

Fellowship

National Institutes of Health Clinical Center (1985), Immunodermatology

• Animal models of skin disease
• Autoimmune blistering diseases
• Inherited blistering diseases (i.e., epidermolysis bullosa)

Featured Publications

The pathophysiology of autoimmune blistering diseases.

Yancey, K.B. J. Clin. Invest. 2005 115 825-828

Revertant mosaicism: partial correction of a germline mutation in COL17A1 by a frame restoring mutation.

Darling, T.N., Yee, C., Bauer, J.W., Hintner, H., Yancey, K.B. J. Clin. Invest. 1999 103 1371-1377

Autoreactive CD4+ T-cell responses to the extracellular domain of bullous pemphigoid antigen 2 (BPAG2) in patients with bullous pemphigoid.

Budinger, L., Borradori, L., Yee, C., Merk, H.F., Yancey, K.B., Hertl, M. J. Clin. Invest. 1998 102 2082-2089

Passive transfer of anti-laminin 5 antibodies induces subepidermal blisters in neonatal mice.

Lazarova, Z., Yee, C., Darling, T., Briggaman, R.A., Yancey, K.B. J. Clin. Invest. 1996 98 1509-1518

Epiligrin, the major human keratinocye intergrin ligand, is the target of disease in both an acquired autoimmune and an inherited subepidermal blistering skin disease.

Domloge-Hultsch, N., Gammon, W.R., Briggaman, R.A., Gil, S.G., Carter, W.G., Yancey, K.B. J. Clin. Invest. 1992 90 1628-1633

Hair follicle stem cells provide a functional niche for melanocyte stem cells.

Tanimura, S., Tadokoro, Y., Inomata, K., Binh, N.T., Nishie, W., Yamazaki, S., Nakauchi, H., Tanaka, Y., McMillan, J.R., Sawamura, D., Yancey, K., Shimizu, H., Nishimura, E.K. Cell Stem Cell 2011 8 177-187

Sequential intramolecular epitope spreading of humoral responses to human BPAG2 in a transgenic model.

Di Zenzo, G., Calabresi, V., Olasz, E.O., Zambruno, G., Yancey, K.B. J. Invest. Dermatol. 2010 130 1040-1047

Transient Anti-CD40L Co-Stimulation Blockade Prevents Immune Responses against Human Bullous Pemphigoid Antigen 2: Implications for Gene Therapy.

Lanschuetzer, C.M., Olasz, E.B., Lazarova, Z., Yancey, K.B. J. Invest. Dermatol. 2009 129 1203-1207

Humanization of autoantigen.

Nishie, W., Sawamura, D., Goto, M., Ito, K., Shibaki, A., McMillian, J.R., Sakai, K., Nakamura, H., Olasz, E., Yancey, K.B., Akiyama, M., Shimizu H. Nature Medicine 2007 13 378-383

Human bullous pemphigoid antigen 2 in transgenic skin elicits specific IgG in wild type mice.

Olasz, E., Roh, J.Y., Yee, C., Arita, K., Akiyama, M., Shimizu, H., Vogel, J.C., Yancey, K.B. J. Invest. Dermatol. 2007 127 2807-2817

• Board of Directors, Association of Professors of Dermatology (2015-2018)
  
• Board of Directors, Dermatology Foundation (2008-2019)
  
• Board of Directors, Society for Investigative Dermatology (2004-2009)
  
• Deputy Editor, Journal of Investigative Dermatology (2007-2010)
  
• Director, American Board of Dermatology (1997-2005)
  
• President, Dermatology Foundation (2017-2019)
  
• President, Society for Investigative Dermatology (2011-2012)
  
• Sulzberger Award and Lecture, American Academy of Dermatology (2007)
  
• Vice President, American Board of Dermatology (2005)
  

• American Academy of Dermatology
• American Association for the Advancement of Science
• American Dermatological Association
• American Society for Clinical Investigation
• Association of Professors of Dermatology
• Dermatology Foundation
• Society for Investigative Dermatology