Pancreatic islets engineered with SA-FasL protein establish robust localized tolerance by inducing regulatory T cells in mice.
Yolcu ES, Zhao H, Bandura-Morgan L, Lacelle C, Woodward KB, Askenasy N, Shirwan H J. Immunol. 2011 Dec 187 11 5901-9
Induction of tolerance to cardiac allografts using donor splenocytes engineered to display on their surface an exogenous fas ligand protein.
Yolcu ES, Gu X, Lacelle C, Zhao H, Bandura-Morgan L, Askenasy N, Shirwan H J. Immunol. 2008 Jul 181 2 931-9
Ex vivo expansion of CD4+CD25+FoxP3+ T regulatory cells based on synergy between IL-2 and 4-1BB signaling.
Elpek KG, Yolcu ES, Franke DD, Lacelle C, Schabowsky RH, Shirwan H J. Immunol. 2007 Dec 179 11 7295-304
CD4+CD25+ T regulatory cells dominate multiple immune evasion mechanisms in early but not late phases of tumor development in a B cell lymphoma model.
Elpek KG, Lacelle C, Singh NP, Yolcu ES, Shirwan H J. Immunol. 2007 Jun 178 11 6840-8
Senescent fibroblasts resist apoptosis by downregulating caspase-3.
Marcotte R, Lacelle C, Wang E Mech. Ageing Dev. 2004 Oct-Nov 125 10-11 777-83
Designer microarrays: from soup to nuts.
Wang E, Lacelle C, Xu S, Zhao X, Hou M J. Gerontol. A Biol. Sci. Med. Sci. 2002 Nov 57 11 B400-5
Blood-sample processing for the study of age-dependent gene expression in peripheral blood mononuclear cells.
Lacelle C, Riol H, Xu S, Tang YJ, Wang YS, Chuang YL, Lin HS, Chang MC, Liang J, Wang E J. Gerontol. A Biol. Sci. Med. Sci. 2002 Jul 57 7 B285-7
Establishing lymphoblastoid cell lines from frozen blood of extremely old individuals.
Lacelle C, Wang E Mech. Ageing Dev. 2002 Jul 123 10 1415-8
Alterations in TNF- and IL-related gene expression in space-flown WI38 human fibroblasts.
Semov A, Semova N, Lacelle C, Marcotte R, Petroulakis E, Proestou G, Wang E FASEB J. 2002 Jun 16 8 899-901
Identification of high caspase-3 mRNA expression as a unique signature profile for extremely old individuals.
Lacelle C, Xu S, Wang E Mech. Ageing Dev. 2002 Apr 123 8 1133-44