Biography

EDUCATION

Undergraduate

St Xavier's College, Mumbai, India (1999), Lifesciences/Biochemistry

Graduate School

Texas A & M University (2005), Genetics

Research Interest

  • Cancer
  • Genetic basis of Autoimmunity
  • Primary Immunodeficiency Disease
  • Systemic Lupus Erythematosus (SLE)

Publications

Featured Publications LegendFeatured Publications

DNA polymerase-a regulates the activation of type I interferons through cytosolic RNA:DNA synthesis.
Starokadomskyy P, Gemelli T, Rios JJ, Xing C, Wang RC, Li H, Pokatayev V, Dozmorov I, Khan S, Miyata N, Fraile G, Raj P, Xu Z, Xu Z, Ma L, Lin Z, Wang H, Yang Y, Ben-Amitai D, Orenstein N, Mussaffi H, Baselga E, Tadini G, Grunebaum E, Sarajlija A, Krzewski K, Wakeland EK, Yan N, de la Morena MT, Zinn AR, Burstein E Nat. Immunol. 2016 Mar
Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients.
Banchereau R, Hong S, Cantarel B, Baldwin N, Baisch J, Edens M, Cepika AM, Acs P, Turner J, Anguiano E, Vinod P, Kahn S, Obermoser G, Blankenship D, Wakeland E, Nassi L, Gotte A, Punaro M, Liu YJ, Banchereau J, Rossello-Urgell J, Wright T, Pascual V Cell 2016 Mar
Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.
Raj P, Rai E, Song R, Khan S, Wakeland BE, Viswanathan K, Arana C, Liang C, Zhang B, Dozmorov I, Carr-Johnson F, Mitrovic M, Wiley GB, Kelly JA, Lauwerys BR, Olsen NJ, Cotsapas C, Garcia CK, Wise CA, Harley JB, Nath SK, James JA, Jacob CO, Tsao BP, Pasare C, Karp DR, Li QZ, Gaffney PM, Wakeland EK Elife 2016 Feb 5
RNA sequencing reveals the consequences of a novel insertion in dedicator of cytokinesis-8.
Khan S, Kuruvilla M, Hagin D, Wakeland B, Liang C, Vishwanathan K, Gatti RA, Torgersen TR, Abraham RS, Wakeland EK, van Oers NS, de la Morena MT J. Allergy Clin. Immunol. 2016 Feb
Fatty Acid Amide Hydrolase Regulates Peripheral B Cell Receptor Revision, Polyreactivity, and B1 Cells in Lupus.
Pathak S, Kumar KR, Kanta H, Carr-Johnson F, Han J, Bashmakov A, Faure L, Ding H, Vanarsa K, Khan S, Li QZ, Chapman K, Wakeland EK, Mohan C J. Immunol. 2016 Jan
Cutting Edge: Inhibiting TBK1 by Compound II Ameliorates Autoimmune Disease in Mice.
Hasan M, Dobbs N, Khan S, White MA, Wakeland EK, Li QZ, Yan N J. Immunol. 2015 Oct
Activation of nuclear TR3 (NR4A1) by a diindolylmethane analog induces apoptosis and proapoptotic genes in pancreatic cancer cells and tumors.
Yoon K, Lee SO, Cho SD, Kim K, Khan S, Safe S Carcinogenesis 2011 Jun 32 6 836-42
Targeting NR4A1 (TR3) in cancer cells and tumors.
Lee SO, Li X, Khan S, Safe S Expert Opin. Ther. Targets 2011 Feb 15 2 195-206
Nur77 agonists induce proapoptotic genes and responses in colon cancer cells through nuclear receptor-dependent and nuclear receptor-independent pathways.
Cho SD, Yoon K, Chintharlapalli S, Abdelrahim M, Lei P, Hamilton S, Khan S, Ramaiah SK, Safe S Cancer Res. 2007 Jan 67 2 674-83
Molecular mechanism of inhibitory aryl hydrocarbon receptor-estrogen receptor/Sp1 cross talk in breast cancer cells.
Khan S, Barhoumi R, Burghardt R, Liu S, Kim K, Safe S Mol. Endocrinol. 2006 Sep 20 9 2199-214

Honors & Awards

  • George T. EDDS Award for outstanding graduate student, Texas A&M University
    (2003)
  • Department of Defense Predoctoral traineeship grant
    Breast Cancer Research Grant (2002-2005)

Professional Associations/Affiliations

  • American Society of Human Genetics (2010)
  • American Association for Cancer Research (2004-2016)