Sarvjeet Singh, Ph.D.

Assistant Instructor

Department: Internal Medicine

Biography

Dr. Sarvjeet Singh received his Ph.D. (Molecular Biology) in 2007 from one of India’s preeminent biomedical institutions, the Center for Cellular and Molecular Biology (CCMB) located in Hyderabad, India. Dr. Singh’s doctoral work was performed under the guidance of Dr. Ashok Khar, one of India’s renowned immunologists and who is the former Deputy Director of CCMB. Sarvjeet’s Ph.D. work focused on the role of apoptosis in tumor biology. From 2007 to 2013, Dr. Singh was a postdoctoral research fellow in the Mammen Laboratory at UT Southwestern Medical Center. Under the guidance of Dr. Pradeep Mammen, his postdoctoral work focused on investigating the role of redox signaling in modulating myocyte proliferation and differentiation. Dr Singh’s postdoctoral work was partially funded by an American Heart Association Postdoctoral Research Fellowship Grant Award (2009-2011). In addition, he was selected as a finalist for the 2010 Louis N. and Arnold M. Katz Basic Science Research Award. This Award is sponsored by the American Heart Association and represents the highest honor that can be bestowed upon a junior investigator. Finally, in February of 2013, Dr. Singh joined the cardiology research faculty at UT Southwestern Medical Center. Currently, his research efforts are focused on further enhancing our understanding of the molecular mechanisms that regulate skeletal muscle and cardiac growth and regeneration under basal and pathologic conditions.

Education

Graduate School "hamdard University, Delhi , India" (2000), Biochemistry
Graduate School University of Hyderabad - India (2006), Molecular Biology

Research Interests

  • Apoptosis
  • Cardiac Hypertrophy
  • Cell Cycle
  • Redox Signaling and Homeostasis
  • Regeneration and Growth

Publications

Featured Publications Legend

Featured Publications

Calcineurin and its regulator, RCAN1, confer time-of-day changes in susceptibility of the heart to ischemia/reperfusion.

Rotter D, Grinsfelder DB, Parra V, Pedrozo Z, Singh S, Sachan N, Rothermel BA J. Mol. Cell. Cardiol. 2014 May

Immunomodulatory and therapeutic activity of curcumin.

Srivastava RM, Singh S, Dubey SK, Misra K, Khar A Int. Immunopharmacol. 2011 Mar 11 3 331-41

Immunomodulatory effects of curcumin: in-vivo.

Varalakshmi Ch, Ali AM, Pardhasaradhi BV, Srivastava RM, Singh S, Khar A Int. Immunopharmacol. 2008 May 8 5 688-700

Antitumour immune responses.

Mitra R, Singh S, Khar A Expert Rev Mol Med 2003 Jan 5 3 1-19

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Honors/Awards

  • The Louis N. and Arnold M. Katz Basic Science Research Award Finalist
    Competitive award for young investigators in basic cardiovascular research, sponsored by the AHA (2010)
  • AHA South Central Postdoctoral Research Award
    Postdoctoral Fellowship (2009)
  • New Investigator Travel Award
    Competitive award from the American Heart Association to attend the 2009 AHA Basic Cardiovascular Symposium (2009)
  • International Travel Award
    Travel and supportive grant from the Government of India and Cold Spring Harbor Laboratory to attend the 6th Conference on Programmed Cell Death (2005)
  • National Eligibility Test Scholarship
    Predoctoral Fellowship (2001)

Professional Associations/Affiliations

  • Sigma Xi (2012)
  • AAAS (2010)
  • American Heart Association (2009)