Featured Publications
Inhibitory receptors bind Angptls and support blood stem cells and leukemia development
Zheng J*, Umikawa M*, Cui C*, Li J, Chen X, Zhang C, Huynh H, Kang X, Silvany R, Wan X, Ye J, Canto AP, Chen SH, Wang HY, Ward ES, Zhang CC. Nature 2012 485 656-660
Ex vivo expanded hematopoietic stem cells overcome the MHC barrier in allogeneic transplantation
Zheng J, Umikawa M, Zhang S, Huynh H, Silvany R, Chen BPC, Chen L, Zhang CC. Cell Stem Cell 2011 9 119-130
Metabolic Profiling Enriches for Hematopoietic Stem Cells
Simsek T, Kocabas F, Zheng J, DeBerardinis RJ, Olson EN, Schneider JW, Zhang CC*, Sadek HA* Cell Stem Cell 2010 7 380-390
Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal
Zhang CC, Steele AD, Lindquist S, Lodish HF Proc Natl Acad Sci U S A 2006 103 2184-2189
Angiopoietin-like proteins stimulate ex vivo expansion of hematopoietic stem cells
Zhang CC, Kaba M, Ge G, Xie K, Tong W, Hug C, Lodish HF Nature Medicine 2006 12 240-245
Angiopoietin-like protein 3 supports the activity of mouse hematopoietic stem cells in the bone marrow niche
Zheng J, Huynh H, Umikawa M, Silvany R, Zhang CC Blood 2011 117 470-479
IGF Binding Protein 2 Supports the Survival and Cycling of Hematopoietic Stem Cells
Huynh H, Zheng J, Umikawa M, Zhang C, Silvany R, Iizuka S, Holzenberger M, Zhang W, Zhang CC Blood 2011 118
IGFBP2 secreted by a tumorigenic cell line supports ex vivo expansion of mouse hematopoietic stem cells
Huynh H, Iizuka S, Kaba M, Kirak O, Zheng J, Lodish HF, Zhang CC Stem Cells 2008 26 1628-1635