Dr. Wang grew up in Houston and received his B.S. from Stanford University. He then enrolled in the Tri-Institutional M.D./Ph.D. Program in New York. He completed his graduate work with Titia de Lange at The Rockefeller University where he studied the role of telomeres in the growth of both normal and transformed cells.
After receiving his M.D. from Cornell in 2006, he returned to Texas to complete his internship in internal medicine and residency in dermatology at UT Southwestern. He received support from the UTSW Physician Scientist Training Program and the Dermatology Foundation to do a research fellowship with Beth Levine.
His research focuses on pathways central to both the development of normal skin and non-melanoma skin cancer tumorigenesis. Specific areas of interest include autophagy and glucose transport. Research in the laboratory is supported by a K08 grant from the NIH/NCI and a Career Award for Medical Scientists from the Burroughs Wellcome Fund.
Dr. Wang practices general dermatology and has an interest in immunosuppressed patients with skin cancers or viral infections, including emerging polyomaviruses.
- Graduate School
- Rockefeller University (2005)
- Medical School
- Weill Cornell Medical College (2006)
- UT Southwestern Medical Center (2007), Internal Medicine
- UT Southwestern Medical Center (2010), Dermatology
- Merkel Cell Carcinoma
- Skin Cancer
- A Protein Kinase C Phosphorylation Motif in GLUT1 Affects Glucose Transport and is Mutated in GLUT1 Deficiency Syndrome.
- Lee EE, Ma J, Sacharidou A, Mi W, Salato VK, Nguyen N, Jiang Y, Pascual JM, North PE, Shaul PW, Mettlen M, Wang RC Mol. Cell 2015 May
- A Primary Melanoma and its Asynchronous Metastasis Highlight the Role of BRAF, CDKN2A, and TERT.
- Hosler GA, Davoli T, Mender I, Litzner B, Choi J, Kapur P, Shay JW, Wang RC J. Cutan. Pathol. 2014 Nov
- Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation.
- Wang RC, Wei Y, An Z, Zou Z, Xiao G, Bhagat G, White M, Reichelt J, Levine B Science 2012 Nov 338 6109 956-9
- Viral-associated trichodysplasia spinulosa: a case with electron microscopic and molecular detection of the trichodysplasia spinulosa-associated human polyomavirus.
- Matthews MR, Wang RC, Reddick RL, Saldivar VA, Browning JC J. Cutan. Pathol. 2011 May 38 5 420-31
- Homologous recombination generates T-loop-sized deletions at human telomeres.
- Wang RC, Smogorzewska A, de Lange T Cell 2004 Oct 119 3 355-68
- Glutathione Depletion, Pentose Phosphate Pathway Activation, and Hemolysis in Erythrocytes Protecting Cancer Cells from Vitamin C Induced Oxidative Stress.
- Zhang ZZ, Lee EE, Sudderth J, Yue Y, Zia A, Glass D, DeBerardinis RJ, Wang RC J. Biol. Chem. 2016 Sep
- Two cases of trichodysplasia spinulosa responsive to compounded topical cidofovir 3% cream.
- Leitenberger JJ, Abdelmalek M, Wang RC, Strasfeld L, Hopkins RS JAAD Case Rep 2015 Nov 1 6 S33-5
- The Cause of Follicular Spicules in Multiple Myeloma.
- Hosler GA, Weibel L, Wang RC JAMA Dermatol 2014 Dec
- Polyomavirus-Associated Trichodysplasia Spinulosa Involves Hyperproliferation, pRB Phosphorylation and Upregulation of p16 and p21.
- Kazem S, van der Meijden E, Wang RC, Rosenberg AS, Pope E, Benoit T, Fleckman P, Feltkamp MC PLoS ONE 2014 9 10 e108947
- Calcipotriol induces autophagy in HeLa cells and keratinocytes.
- Wang RC, Levine B J. Invest. Dermatol. 2011 Apr 131 4 990-3
Honors & Awards
- Burroughs Wellcome Fund Career Award for Medical Scientists
- The Dermatology Foundation Physician Scientist Career Development Award
- Stanford University President’s Scholar
- American Academy of Dermatology (2011)
- Society of Investigative Dermatology (2007)