Dr. Wang grew up in Houston and received his B.S. from Stanford University. He then enrolled in the Tri-Institutional M.D./Ph.D. Program in New York. He completed his graduate work with Titia de Lange at The Rockefeller University where he studied the role of telomeres in the growth of both normal and transformed cells.
After receiving his M.D. from Cornell in 2006, he returned to Texas to complete his internship in internal medicine and residency in dermatology at UT Southwestern. He received support from the UTSW Physician Scientist Training Program and the Dermatology Foundation to do a research fellowship with Beth Levine, M.D.
Currently, his research focuses on whether autophagy, a cellular ‘recycling’ process, can prevent the development of non-melanoma skin cancer. Another area of interest in the lab is human polyomaviruses and their role in skin diseases, including cancer. Research in the laboratory is supported by a K08 grant from the NIH/NCI and a Career Award for Medical Scientists from the Burroughs Wellcome Fund.
Dr. Wang practices general dermatology and has an interest in immunosuppressed patients with skin cancers or viral infections.
|Graduate School||Rockefeller University (2005)|
|Medical School||Weill Cornell Medical College (2006)|
|Internship||UT Southwestern Medical Center (2007), Internal Medicine|
|Residency||UT Southwestern Medical Center (2010), Dermatology|
- Atopic Dermatitis
- Chronic Cellulitis
- Merkel Cell Carcinoma
- Nevi (Moles)
- Patients with Multiple Moles
- Pigmented Lesions
- Previous Skin Cancers
- Skin Check
- Skin Disorders
- Transplant Patients
- Merkel Cell Carcinoma
- Skin Cancer
- A Primary Melanoma and its Asynchronous Metastasis Highlight the Role of BRAF, CDKN2A, and TERT.
- Hosler GA, Davoli T, Mender I, Litzner B, Choi J, Kapur P, Shay JW, Wang RC J. Cutan. Pathol. 2014 Nov
- Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation.
- Wang RC, Wei Y, An Z, Zou Z, Xiao G, Bhagat G, White M, Reichelt J, Levine B Science 2012 Nov 338 6109 956-9
- Viral-associated trichodysplasia spinulosa: a case with electron microscopic and molecular detection of the trichodysplasia spinulosa-associated human polyomavirus.
- Matthews MR*, Wang RC*, Reddick RL, Saldivar VA, Browning JC. J Cutan Pathol. May 2011 38(5) 420-31
- Homologous recombination generates T-loop-sized deletions at human telomeres.
- Wang RC, Smogorzewska A, de Lange T Cell 2004 Oct 119 3 355-68
- Polyomavirus-Associated Trichodysplasia Spinulosa Involves Hyperproliferation, pRB Phosphorylation and Upregulation of p16 and p21.
- Kazem S, van der Meijden E, Wang RC, Rosenberg AS, Pope E, Benoit T, Fleckman P, Feltkamp MC PLoS ONE 2014 9 10 e108947
- Calcipotriol induces autophagy in HeLa cells and keratinocytes.
- Wang RC, Levine B. J Invest Dermatol. April 2011 131(4) 990-3
- Subclinical Lung Disease, Macrocytosis and Premature Graying in Kindreds with Telomerase (TERT) Mutations.
- Diaz de Leon A, Cronkhite JT, Yilmaz C, Brewington C, Wang R, Xing C, Hsia CC, Garcia CK. Chest February 2011
- Autophagy in cellular growth control.
- Wang RC, Levine B. FEBS Lett. April 2010 584(7) 1417-26
- Engineered telomere degradation models dyskeratosis congenita.
- Hockemeyer D, Palm W, Wang RC, Couto SS, de Lange T. Genes Dev. July 2008 22(13) 1773-85
- Tel2 regulates the stability of PI3K-related protein kinases
- Takai H, Wang RC, Takai KK, Yang H, de Lange T Cell December 2007 131(7) 2167-77
Honors & Awards
- Burroughs Wellcome Fund Career Award for Medical Scientists
- The Dermatology Foundation Physician Scientist Career Development Award
- Stanford University President’s Scholar
- American Academy of Dermatology (2011)
- Society of Investigative Dermatology (2007)