Rashmin Savani, M.D.

Professor

Endowed Title: The William Buchanan Chair in Pediatrics

Department: Pediatrics

Graduate Programs: Integrative Biology

Biography

Rashmin Savani was born in Masaka, Uganda, received his primary education there,and then completed schooling at King Edward VII School in Sheffield, England (1977). He obtained his medical degree from the University of Sheffield (1982). He undertook internships in Internal Medicine, General Surgery and Obstetrics & Gynecology from 1982 to 1984. He was a pediatric resident at Duke University Medical Center (1984-1987) and a fellow in Neonatology (1987-1989) and in Pulmonary Biology (1989-1991) at Cincinnati Children’s Medical Center. He then moved to the University of Manitoba and Winnipeg Children’s Hospital where he was an Assistant Professor of Pediatrics in the Section of Neonatology (1991-1996). He undertook further postgraduate training in Cell & Molecular Biology at the Manitoba Institute of Cell Biology (1991-1994) after which he had an independent laboratory at the Institute. He was recruited to the University of Pennsylvania and Children’s Hospital of Philadelphia (1996-2006) and rose to the rank of Associate Professor with Tenure in 2002. His research focus has been on lung injury and development, including inflammation and angiogenesis. He has maintained continuous extramural funding since 1998. Dr. Savani moved from CHOP/PENN in 2006 to become Professor of Pediatrics. He was awarded the William Buchanan Chair in Pediatrics in 2006 and is currently Division Director of Neonatal-Perinatal Medicine and Associate Director of Pulmonary & Vascular Biology in the Department of Pediatrics.

Education

Medical School The University of Sheffield Medical School (1982)
Internship Royal Hallamshire Hospital (1983), Internal Medicine
Internship Northern General Hospital (1983), General Surgery
Internship Peterborough District Hospital (1984), Obstetrics & Gynecology
Residency Duke University Medical Center (1987), Pediatrics
Fellowship Cincinnati Children's Hospital Medical Center (1991), Neonatal-perinatal Medicine
Fellowship University of Manitoba (1994), Cell Biology

Specialty Areas

Clinical Interests

  • Bronchiopulmonary Dysplasia (BPD)
  • Chronic Lung Disease (CLD)

Research Interests

  • Hyaluronan

Publications

Featured Publications Legend

Featured Publications

Hormonal regulation of alveolarization: structure-function correlation.

Garber SJ, Foley JP, Godinez RI, Godinez MH, Gow AJ, Savani RC Respiratory Research 2006 7/1 47

Loss of PECAM-1 function impairs lung alveolarization.

DeLisser, Helmke, Cao, Pooler, Taichman, Fehrenbach, Zaman, Cui, Mohan, Baldwin, Davis, Savani J. Biol. Chem 2006 28/13 8724-8731

Surfactant Composition and Function in a Primate Model of Infant Chronic Lung Disease: Effects of Inhaled Nitric Oxide.

Ballard PI, Gonazles, LW, Godinez, RI, Godinez MH, Savani RC, McCurnin DC, Gibson LL, Yoder BA, Kerecman JD, Brubb PH, Shaul PW Pediatric Research 2005 59/1 157-162

Alveolar Surgactant Protein D Content Modulates Bleomycin Induced Lung Injury

Casey, Kaplan, Atochina, Gow, Kadire, Tomer, Fisher, Hawgood, Savani, Beers. Am. J. Respir. Crit Care Med. 2005 172/7 869-877

Expression and role of the hyaluronan receptor RHAMM in Inflammation after bleomycin injury

Zaman A, Cui Z, Foley JP, Grimm PC, DeLisser HM, Savani RC Am J Respir Cell Mol Biol 2005 33 447-454

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Honors/Awards

  • Honorary Masters of Arts
    University of Pennsylvania School of Medicine (2002)
  • Young Investigator Award, Perinatal Pediatrics
    American Academy of Pediatrics (1998)
  • Young Investigator Award, Basic Science
    Eastern Society for Pediatric Research (1997)

Professional Associations/Affiliations

  • Member, American Pediatric Society
  • Member, American Physiological Society
  • Member, American Society for Biochemistry and Molecular Biology
  • Member, The International Society for Hyaluronan Science