Biography for Dr. Jeffrey Zigman

Jeffrey M. Zigman, M.D., Ph.D., is a tenured Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center with a secondary appointment in the Department of Psychiatry.

Dr. Zigman holds both the Diana and Richard C. Strauss Professorship in Biomedical Research and the Mr. and Mrs. Bruce G. Brookshire Professorship in Medicine.

An endocrinologist, Dr. Zigman specializes in treating patients with thyroid cancer and thyroid nodules. He played an active role in establishing UT Southwestern’s thyroid nodule and thyroid cancer clinic.

A Fellow of the Obesity Society, Dr. Zigman is American Board of Internal Medicine-certified in endocrinology, diabetes, and metabolism.

He also is certified by the American Association of Clinical Endocrinologists in neck ultrasound, thyroid ultrasound, and ultrasound-guided fine-needle aspiration biopsy. A recognized expert in performing these procedures, he instructs endocrinology trainees at UT Southwestern and other endocrinologists around the world in how to do them.

Dr. Zigman is affiliated with the Division of Hypothalamic Research and the Division of Endocrinology, as well as with the Integrative Biology Graduate Program and the Neuroscience Graduate Program.

His research is aimed at better understanding the neuro-hormonal framework underlying complex eating behaviors, including those linked to stress, depression and blood glucose control.

The Zigman Lab focuses largely on the hormone ghrelin, including mechanisms controlling ghrelin secretion and mechanisms by which the ghrelin system engages feeding, blood glucose-related processes, as well as antidepressant behaviors. The lab also investigates other hormones released by the stomach.

The lab’s researchers study conditions that include obesity, depression, psychosocial stress, diabetes, cachexia, and Prader-Willi syndrome.

Dr. Zigman has published more than 60 scholarly articles and delivered scores of invited lectures nationally and internationally.

He serves as a consulting editor for Molecular Metabolism and as an ad hoc reviewer for a number of respected academic journals.

He joined the UT Southwestern faculty in 2006.

Dr. Zigman earned his medical degree at the University of Chicago Pritzker School of Medicine. He completed an internal medicine residency at University of Chicago Hospitals and a fellowship in endocrinology, diabetes, and metabolism at Beth Israel Deaconess Medical Center in Boston.

He also holds a doctoral degree in biochemistry and molecular biology from the University of Chicago – earned through the university’s M.D.-Ph.D. Program – and a bachelor’s degree in biological sciences from Cornell University.

Professional Associations & Affiliations

  • American Society for Clinical Investigation (2012)
  • American Thyroid Association (2009)
  • The Endocrine Society (2009)
  • The Obesity Society (2008)
  • American Diabetes Association (2004)
  • American Association of Clinical Endocrinologists (2000)

Honors and Awards

  • Top Doctor
    Named by Castle Connolly (2015)
  • Patricia Usher Memorial Lecture speaker
    Division of Endocrinology, Diabetes & Metabolism, Beth Israel Deaconess Medical Center, Boston (2014)
  • Class of 2014 (MS2) Outstanding Teaching Award 2011-2012
    The University of Texas Southwestern Medical Center (2012)
  • Diana and Richard C. Strauss Professorship in Biomedical Research
    (2012)
  • Election as a member of the American Society for Clinical Investigation
    American Society for Clinical Investigation (2012)
  • Mr. and Mrs. Bruce G. Brookshire Professorship in Medicine
    (2012)
  • Class of 2013 (MS2) Outstanding Teaching Award 2010-2011
    The University of Texas Southwestern Medical Center (2011)
  • Top Doctor
    U.S. News & World Report (2011)
  • Class of 2013 (MS1) Outstanding Teaching Award in Physiology 2009-2010
    The University of Texas Southwestern Medical Center (2010)
  • UTSW Medical Center Disease Oriented Clinical Scholar
    The University of Texas Southwestern Medical Center (2006)
  • Graduation Cum Laude and with distinction in all subjects; Phi Beta Kappa National Honor Society from Cornell University
    Cornell University (1989)
  • National Institutes of Health Medical Scientist Training Program
    The University of Chicago (1989)