Education

Graduate School Iowa State University (1992)
Graduate School Iowa State University (1993)

Research Interest

  • Body Weight Homeostasis
  • Central Autonomic Control
  • Diabetes and Glucose Homeostasis
  • Neurobiology and Neuroanatomy of the Hypothalamus

Publications

Featured Publications LegendFeatured Publications

Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels.
Sohn JW, Xu Y, Jones JE, Wickman K, Williams KW, Elmquist JK Neuron 2011 Aug 71 3 488-97
Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus.
Kim KW, Zhao L, Donato J, Kohno D, Xu Y, Elias CF, Lee C, Parker KL, Elmquist JK Proc. Natl. Acad. Sci. U.S.A. 2011 Jun 108 26 10673-8
Induction of leptin resistance by activation of cAMP-Epac signaling.
Fukuda M, Williams KW, Gautron L, Elmquist JK Cell Metab. 2011 Mar 13 3 331-9
Melanocortin-4 receptors expressed by cholinergic neurons regulate energy balance and glucose homeostasis.
Rossi J, Balthasar N, Olson D, Scott M, Berglund E, Lee CE, Choi MJ, Lauzon D, Lowell BB, Elmquist JK Cell Metab. 2011 Feb 13 2 195-204
5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver.
Xu Y, Berglund ED, Sohn JW, Holland WL, Chuang JC, Fukuda M, Rossi J, Williams KW, Jones JE, Zigman JM, Lowell BB, Scherer PE, Elmquist JK Nat. Neurosci. 2010 Dec 13 12 1457-9
Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility.
Hill JW, Elias CF, Fukuda M, Williams KW, Berglund ED, Holland WL, Cho YR, Chuang JC, Xu Y, Choi M, Lauzon D, Lee CE, Coppari R, Richardson JA, Zigman JM, Chua S, Scherer PE, Lowell BB, Brüning JC, Elmquist JK Cell Metab. 2010 Apr 11 4 286-97
The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity.
Coppari R, Ichinose M, Lee CE, Pullen AE, Kenny CD, McGovern RA, Tang V, Liu SM, Ludwig T, Chua SC, Lowell BB, Elmquist JK Cell Metab. 2005 Jan 1 1 63-72
Activation of central melanocortin pathways by fenfluramine.
Heisler LK, Cowley MA, Tecott LH, Fan W, Low MJ, Smart JL, Rubinstein M, Tatro JB, Marcus JN, Holstege H, Lee CE, Cone RD, Elmquist JK Science 2002 Jul 297 5581 609-11

Honors & Awards

  • NPA Garnett-Powers & Associates Inc., 2014 Mentor Award
    National Postdoctoral Association (2014)
  • Outstanding Scientific Achievement Award
    American Diabetes Association (2014)
  • Ernst Oppenheimer Award, The Endocrine Society
    (2008)
  • Iowa State University Excellence in Research Award
    (1993)