Elizabeth Maher, M.D., Ph.D.

Associate Professor

Endowed Title: Theodore H. Strauss Professorship in Neuro-Oncology

Department: Internal Medicine, Neurology & Neurotherapeutics

Education

Graduate School McGill University (1989)
Medical School McGill University (1993)
Internship/Residency University of Toronto Hospitals - IM Residency (1996), Internal Medicine
Fellowship Dana Farber Cancer Center/Brigham & Women's Hospital (1999), Hematology and Oncology

Specialty Areas

Clinical Interests

  • Brain Cancer
  • Brain Metastases
  • Malignant Brain Tumor
  • Malignant Gliomas
  • Oncology Clinical Trials
  • Primary Central Nervous System Lymphoma

Research Interests

  • Development of improved imaging techniques for brain tumors
  • Primary and metastatic brain tumors
  • Role of altered metabolism in the progression of malignant gliomas.

Publications

Featured Publications Legend

Featured Publications

T(2) measurement of J-coupled metabolites in the human brain at 3T.

Ganji SK, Banerjee A, Patel AM, Zhao YD, Dimitrov IE, Browning JD, Sherwood Brown E, Maher EA, Choi C NMR Biomed 2011 Aug

The landscape of somatic copy-number alteration across human cancers.

Beroukhim R, Mermel CH, Porter D, Wei G, Raychaudhuri S, Donovan J, Barretina J, Boehm JS, Dobson J, Urashima M, Mc Henry KT, Pinchback RM, Ligon AH, Cho YJ, Haery L, Greulich H, Reich M, Winckler W, Lawrence MS, Weir BA, Tanaka KE, Chiang DY, Bass AJ, Loo A, Hoffman C, Prensner J, Liefeld T, Gao Q, Yecies D, Signoretti S, Maher E, Kaye FJ, Sasaki H, Tepper JE, Fletcher JA, Tabernero J, Baselga J, Tsao MS, Demichelis F, Rubin MA, Janne PA, Daly MJ, Nucera C, Levine RL, Ebert BL, Gabriel S, Rustgi AK, Antonescu CR, Ladanyi M, Letai A, Garraway LA, Loda M, Beer DG, True LD, Okamoto A, Pomeroy SL, Singer S, Golub TR, Lander ES, Getz G, Sellers WR, Meyerson M Nature 2010 Feb 463 7283 899-905

The telomerase antagonist, imetelstat, efficiently targets glioblastoma tumor-initiating cells leading to decreased proliferation and tumor growth.

Marian CO, Cho SK, McEllin BM, Maher EA, Hatanpaa KJ, Madden CJ, Mickey BE, Wright WE, Shay JW, Bachoo RM Clin. Cancer Res. 2010 Jan 16 1 154-63

A genome-wide screen reveals functional gene clusters in the cancer genome and identifies EphA2 as a mitogen in glioblastoma.

Liu F, Park PJ, Lai W, Maher E, Chakravarti A, Durso L, Jiang X, Yu Y, Brosius A, Thomas M, Chin L, Brennan C, DePinho RA, Kohane I, Carroll RS, Black PM, Johnson MD Cancer Res. 2006 Nov 66 22 10815-23

Phase I/II study of Imatinib Mesylate (Gleevac) for recurrent malignant gliomas (North American Brain Tumor Consortium Study 99-08).

Wen P, Yung A, Lamborn K, Dahia P, Wang Y, Peng B, Abrey L, Raizer J, Cloughesy T, Fink K, Gilbert M, Chang S, Junck L, Schiff D, Leiberman F, Fine H, Mehta M, Robins H, DeAngelis L, Groves M, Puduvalli V, Levin V, Conrad C, Maher E, Aldape K, Hayes M, Letvak L, Egorin M, Capdeville R, Kaplan R, Murgo A, Stiles C, Prados M. Clinical Cancer Research 2006 12(16) 4899-48907

Results 1-10 of 15

Professional Associations/Affiliations

  • Society for Neuro-Oncology (2003)
  • American Society of Clinical Oncology (2001)