Education

Medical School
Universidad Complutense de Madrid (1983), Medicine
Fellowship
University of South Florida - St. Petersburg, FL (1988), Research
Residency
University of South Florida - St. Petersburg, FL (1991), Pediatrics
Fellowship
University of South Florida - St. Petersburg, FL (1993), Allergy & Immunology
Fellowship
University of South Florida - St. Petersburg, FL (1995), Immunology

Specialty Areas

Clinical Interest

  • Allergy & Immunology
  • Clinical Immunology
  • Primary Immunodeficiency Diseases
  • Research Interest

    • Discovery of novel genes associated with primary immunodeficiency syndromes
    • Long term clinical outcomes of patients with chronic granulomatous disease
    • Long term clinical outcomes of patients with X-linked Hyper IgM syndrome
    • MicroRNAs in primary immunodeficiency disorders

    Publications

    Featured Publications LegendFeatured Publications

    Novel nonsense gain-of-function NFKB2 mutations associated with a combined immunodeficiency phenotype.
    Kuehn HS, Niemela JE, Sreedhara K, Stoddard JL, Grossman J, Wysocki CA, de la Morena MT, Garofalo M, Inlora J, Snyder MP, Lewis DB, Stratakis CA, Fleisher TA, Rosenzweig SD Blood 2017 08
    Natural Killer Cells from Patients with Recombinase-Activating Gene and Non-Homologous End Joining Gene Defects Comprise a Higher Frequency of CD56(bright) NKG2A(+++) Cells, and Yet Display Increased Degranulation and Higher Perforin Content.
    Dobbs K, Tabellini G, Calzoni E, Patrizi O, Martinez P, Giliani SC, Moratto D, Al-Herz W, Cancrini C, Cowan M, Bleesing J, Booth C, Buchbinder D, Burns SO, Chatila TA, Chou J, Daza-Cajigal V, Ott de Bruin LM, de la Morena M, Di Matteo G, Finocchi A, Geha R, Goyal RK, Hayward A, Holland S, Huang CH, Kanariou MG, King A, Kaplan B, Kleva A, Kuijpers TW, Lee BW, Lougaris V, Massaad M, Meyts I, Morsheimer M, Neven B, Pai SY, Plebani A, Prockop S, Reisli I, Soh JY, Somech R, Torgerson TR, Kim YJ, Walter JE, Gennery AR, Keles S, Manis JP, Marcenaro E, Moretta A, Parolini S, Notarangelo LD Front Immunol 2017 8 798
    Clinical Phenotypes of Hyper-IgM Syndromes.
    de la Morena MT J Allergy Clin Immunol Pract 2016 Nov - Dec 4 6 1023-1036
    Reply.
    Bonilla FA, Chapel H, Costa-Carvalho BT, Cunningham-Rundles C, de la Morena MT, Espinosa-Rosales FJ, Hammarström L, Nonoyama S, Quinti I, Routes JM, Tang ML, Warnatz K J Allergy Clin Immunol Pract 2016 Sep-Oct 4 5 1019-20
    Long term outcomes of 176 patients with X-linked hyper IgM syndrome treated with or without hematopoietic cell transplantation.
    de la Morena MT, Leonard D, Torgerson TR, Cabral-Marques O, Slatter M, Aghamohammadi A, Chandra S, Murguia-Favela L, Bonilla F, Kanariou M, Damrongwatanasuk R, Kuo CY, Dvorak CC, Meyts I, Chen K, Kobrynski L, Kapoor N, Richter D, DiGiovanni D, Dhalla F, Farmaki E, Speckmann C, Espanol T, Shcherbina A, Hanson C, Litzman J, Routes J, Wong M, Fuleihan R, Seneviratne SL, Small TN, Janda A, Bezrodnik L, Seger R, Raccio AG, Edgar JD, Chou J, Abbott JK, van Montfrans J, Gonzalez-Granado LI, Bunin N, Kutukculer N, Gray P, Seminario G, Pasic S, Aquino V, Wysocki C, Abolhassani H, Grunebaum E, Dorsey M, Costa Carvalho BT, Condino-Neto A, Cunningham-Rundles C, Knutsen AP, Sleasman J, Chapel H, Ochs HD, Filipovich A, Cowan M, Gennery A, Cant A, Notarangelo LD, Roifman C J. Allergy Clin. Immunol. 2016 Sep
    MicroRNA-205 maintains T cell development following stress by regulating Forkhead box N1 and selected chemokines.
    Hoover AR, Dozmorov I, MacLeod J, Du Q, de la Morena MT, Forbess J, Guleserian K, Cleaver OB, van Oers NS J. Biol. Chem. 2016 Sep
    Rapid molecular diagnostics of severe primary immunodeficiency determined by using targeted next-generation sequencing.
    Yu H, Zhang VW, Stray-Pedersen A, Hanson IC, Forbes LR, de la Morena MT, Chinn IK, Gorman E, Mendelsohn NJ, Pozos T, Wiszniewski W, Nicholas SK, Yates AB, Moore LE, Berge KE, Sorte H, Bayer DK, ALZahrani D, Geha RS, Feng Y, Wang G, Orange JS, Lupski JR, Wang J, Wong LJ J. Allergy Clin. Immunol. 2016 Jul
    DNA polymerase-a regulates the activation of type I interferons through cytosolic RNA:DNA synthesis.
    Starokadomskyy P, Gemelli T, Rios JJ, Xing C, Wang RC, Li H, Pokatayev V, Dozmorov I, Khan S, Miyata N, Fraile G, Raj P, Xu Z, Xu Z, Ma L, Lin Z, Wang H, Yang Y, Ben-Amitai D, Orenstein N, Mussaffi H, Baselga E, Tadini G, Grunebaum E, Sarajlija A, Krzewski K, Wakeland EK, Yan N, de la Morena MT, Zinn AR, Burstein E Nat. Immunol. 2016 Mar
    Methylotroph Infections and Chronic Granulomatous Disease.
    Falcone EL, Petts JR, Fasano MB, Ford B, Nauseef WM, Neves JF, Simões MJ, Tierce ML, de la Morena MT, Greenberg DE, Zerbe CS, Zelazny AM, Holland SM Emerging Infect. Dis. 2016 Mar 22 3 404-9
    RNA sequencing reveals the consequences of a novel insertion in dedicator of cytokinesis-8.
    Khan S, Kuruvilla M, Hagin D, Wakeland B, Liang C, Vishwanathan K, Gatti RA, Torgersen TR, Abraham RS, Wakeland EK, van Oers NS, de la Morena MT J. Allergy Clin. Immunol. 2016 Feb

    Books

    Featured Books Legend Featured Books

    Honors & Awards

    • Best Pediatric Specialists
      D Magazine (2013-2016)
    • Best Doctors
      D Magazine (2012)

    Professional Associations/Affiliations

    • European Society for Immunodeficiencies (2014)
    • Clinical Immunology Society (2012)
    • Dallas County Medical Association (2005)
    • Pediatric Society of Greater Dallas (2005)
    • Texas Medical Association (2005)
    • American Academy of Pediatrics (1999)
    • International Society for Heart and Lung Transplantation (1999-2005)
    • American Academy of Allergy, Asthma & Immunology (1997)