Featured Publications
On the spontaneous emergence of polarity
Altschuler SJ, Angenent SB, Wang Y, Wu LF Nature August 2008 454 886-890
Image-based multivariate profiling of drug responses from single cells
Loo, L.H., Wu, L., Altschuler, S.J. Nature Methods May 2007 4 445
Endocytosis optimizes the dynamic localization of membrane proteins that regulate cortical polarity
Marco, E., Wedlich-Soldner, R., Li, R., Altschuler, S.J., Wu, L.F. Cell April 2007 129 411
Multi-dimensional drug profiling by automated microscopy.
Perlman, Z.E., Slack, M.D., Feng, Y., Mitchison, T.J., Wu, L.F., Altschuler, S.J. Science 2004 306(5699) 1194-1198
Spontaneous cell polarization through actomyosin-based delivery of the Cdc42 GTPase.
Wedlich-Soldner, R., Altschuler, S.J., Wu, L.F., Li, R. Science 2003 299(5610) 1231-1235
On the spontaneous emergence of polarity
Altschuler SJ, Angenent SB, Wang Y, Wu LF Nature August 2008 454 886-890
An actin-based wave generator organizes cell motility
Weiner, O.D., Marganski, W.A., Wu, L.F., Altschuler, S.J., Krischner, M.W. PLOS Biology August 2007 5 221
Image-based multivariate profiling of drug responses from single cells
Loo, L.H., Wu, L., Altschuler, S.J. Nature Methods May 2007 4 445
Endocytosis optimizes the dynamic localization of membrane proteins that regulate cortical polarity
Marco, E., Wedlich-Soldner, R., Li, R., Altschuler, S.J., Wu, L.F. Cell April 2007 129 411
Systems-level analyses identify extensive coupling among gene expression machines
Maciag, K., Altschuler, S.J., Slack, M.D., Krogan, N.J., Emili, A., Greenblatt, J.F., Maniatis, T., Wu, L.F. Molecular Systems Biology January 2006 2 1