Jinming Gao, Ph.D.

Download Curriculum Vitae

Jinming Gao received his BS degree in Chemistry at Peking University in June 1991. He came to the US and carried out graduate studies at Harvard University under the supervision of Dr. G. M. Whitesides.  In May 1996, he received a PhD degree in Medicinal Chemistry with thesis research focused on rational drug design and protein charge ladders. Following his doctoral studies, he completed his postdoctoral training in Biomedical Engineering under Dr. R. S. Langer at Massachusetts Institute of Technology.

In August 1998, Dr. Gao joined the faculty of Biomedical Engineering at Case Western Reserve University in Cleveland, Ohio. He was promoted to Associate Professor with tenure in Biomedical Engineering and Radiology in April 2004.  In July 2005, Dr. Gao moved his lab to Dallas, Texas, where he currently holds a primary appointment as Professor (with tenure) of Oncology and Pharmacology in the Simmons Comprehensive Cancer Center at UT Southwestern and a joint appointment in Chemistry and Bioengineering at UT Dallas.

Using a highly-interdisciplinary approach, Dr. Gao's lab is focusing on development of multi-functional nanomedicine platforms that incorporate tumor targeting, imaging ultrasensitivity, and controlled drug release for cancer-targeted therapy.

 

Undergraduate	Peking University - China (), Chemistry
Graduate School	Harvard University (1996)

• Probing lysosome catabolism by nanoparticles
• Theranostic nanomedicine for cancer-targeted drug delivery
• Tumor-activatable imaging nanoprobes

Featured Publications

Beta-Lapachone Micellar Nanotherapeutics for Non-Small Cell Lung Cancer Therapy

Blanco, E.; Bey, E.A.; Khemtong, C.; Yang, S.; Setti-Guthi, J.; Chen, H.; Kessinger, C.; Garnevale, K.; Bornmann, W.; Boothman, D.; Gao, J. Cancer Res. 2010 70 3896-3904

In Vivo Off Resonance Saturation Magnetic Resonance Imaging of alpha(v)beta(3)-Targeted Superparamagnetic Nanoparticles

Khemtong, C.; Kessinger, C.W.; Ren, J.; Bey, E.; Yang, S.G.; Guthi, J.; Boothman, D.A., Sherry, A.D.; Gao, J. Cancer Res. 2009 69 1651-1658

Theranostic Nanomedicine for Cancer

Sumer, B.; Gao, J. Nanomedicine 2008 3 137

Multifunctional Polymeric Micelles as Cancer-Targeted, MRI-Ultrasensitive Drug Delivery Systems

Nasongkla N, Bey EA, Ren J, Ai H, Khemtong C, Setti JG, Chin SF, Sherry AD, Boothman DA, Gao J Nano Letters 2006 6 2427-2430

Functional Arteries Grown in Vitro

Niklason, L.; Gao, J.; Abbott, W.; Hirschi, K.; Houser, S.; Marini, R.; Langer, R. Science 1999 5413/284 489-493

Evaluating Electrostatic Contributions to Binding with the Use of Protein Charge Ladders

Gao, J.; Mammen, M.; Whitesides, G. M. Science 1996 272/5261 535-537

Intratumoral Delivery of beta-Lapachone via Polymer Implants for Prostate Cancer Therapy

Dong, Y.; Chin, S.F.; Blanco, E.; Bey, E.A.; Kabbani, W.; Xie, X.J.; Bornmann, W.G.; Boothman, D.A. Gao, J. Clin. Cancer Res. 2009 15 131-139

cRGD-Functionalized Polymer Micelles for Targeted Doxorubicin Delivery

Nasongkla, N.; Shuai, X.; Ai, H.; Weinberg, B.D.; Pink, J.; Boothman, D.A.; Gao, J. Angew. Chem. Int. Ed. 2004 43/46 6323-6327

Magnetite-Loaded Polymeric Micelles as Novel Magnetic Resonance Probes

Ai, H.; Flask, C.; Weinberg, R.; Shuai, X.; Pagel, M.; Farrell, D.; Duerk, J.; Gao, J. Adv. Mater. 2003 17 1949-1952

• Distinguished Scientist Award
  Society of Experimental Biology and Medicine (2011)
• Distinguished Overseas Young Scientist
  National Natural Science Foundation of China (2007)