James Amatruda, M.D., Ph.D.

Associate Professor

Endowed Title: Nearburg Family Professorship in Pediatric Oncology Research; Horchow Family Scholar in Pediatrics

Department: Pediatrics, Internal Medicine, Molecular Biology

Graduate Programs: Cancer Biology

Biography

Harvard University

A.B.

June, 1986

Biochemistry

Washington University

M.D.

May, 1993

Medicine

Washington University

Ph.D.

May, 1993

Cell Biology

Brigham and Women’s Hospital, Boston, MA

Residency

1993-1996

Internal Medicine

Dana-Farber/Partners Cancer Care

Fellowship

1997-1999

Medical Oncology

Boston Children’s/Harvard Medical School

Post-doc

1999-2004

 Hematology-Oncology

Education

Medical School Washington University School of Medicine (1993)
Residency Brigham and Women's Hospital (1996), Internal Medicine
Fellowship Consglio Nazionale delle Ricerche (1997), Molecular Genetics
Fellowship Massachusetts General Hospital, Brigham & Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School (1999), Hematology & Oncology
Fellowship Children's Hospital of Boston (2004), Pediatric Hematology

Specialty Areas

Clinical Interests

  • Germ Cell Tumors
  • Ovarian Cancer
  • Sarcomas
  • Sickle Cell Disease
  • Testicular Cancer

Research Interests

  • Animal Models of Cancer
  • Cancer Genetics
  • DNA Damage Response
  • Testicular Cancer
  • Zebrafish

Publications

Featured Publications Legend

Featured Publications

Fetal and neonatal germ cell tumors.

Frazier AL, Weldon C, Amatruda J Semin Fetal Neonatal Med 2012 Aug 17 4 222-30

In vivo Wnt signaling tracing through a transgenic biosensor fish reveals novel activity domains.

Moro E, Ozhan-Kizil G, Mongera A, Beis D, Wierzbicki C, Young RM, Bournele D, Domenichini A, Valdivia LE, Lum L, Chen C, Amatruda JF, Tiso N, Weidinger G, Argenton F Developmental biology 2012 Apr

Children's Oncology Group's 2013 blueprint for research: Rare tumors.

Rodriguez-Galindo C, Krailo M, Frazier L, Chintagumpala M, Amatruda J, Katzenstein H, Malogolowkin M, Spector L, Pashankar F, Meyers R, Tomlinson G; on behalf of the COG Rare Tumors Disease Committee Pediatr Blood Cancer. 2012 2012 Dec 19. doi:10.1002/pbc.24428. [Epub ahead of print]

C/EBP transcription factors mediate epicardial activation during heart development and injury.

Huang GN, Thatcher JE, McAnally J, Kong Y, Qi X, Tan W, DiMaio JM, Amatruda JF, Gerard RD, Hill JA, Bassel-Duby R, Olson EN. Science 2012 338 6114 1599-603

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Honors/Awards

  • Outstanding Teacher, MS1 Class
    (2011)
  • Outstanding Teacher, MS1 Class
    (2010)
  • Health Care Heroes Award, Dallas Business Journal
    (2009)
  • Outstanding Teacher, MS1 Class
    (2009)
  • Outstanding Teacher, MS1 Class
    (2007)
  • Horchow Family Endowed Scholar in Pediatrics
    (2005)
  • William Guy Forbeck Research Foundation Scholar
    (2003)
  • Arnold Dunne Award
    (1994)
  • Alpha Omega Alpha
    (1993)