Opposing Effect of EGFRWT on EGFRvIII-Mediated NF-?B Activation with RIP1 as a Cell Death Switch.
Puliyappadamba VT, Chakraborty S, Chauncey SS, Li L, Hatanpaa KJ, Mickey B, Noorani S, Shu HK, Burma S, Boothman DA, Habib AA Cell Rep 2013 Aug
The yeast Fun30 and human SMARCAD1 chromatin remodellers promote DNA end resection.
Costelloe T, Louge R, Tomimatsu N, Mukherjee B, Martini E, Khadaroo B, Dubois K, Wiegant WW, Thierry A, Burma S, van Attikum H, Llorente B Nature 2012 Sep 489 7417 581-4
INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells.
Morris C, Tomimatsu N, Richard DJ, Cluet D, Burma S, Khanna KK, Jalinot P Cancer Res. 2012 Apr 72 8 2006-16
Exo1 plays a major role in DNA end resection in humans and influences double-strand break repair and damage signaling decisions.
Tomimatsu N, Mukherjee B, Deland K, Kurimasa A, Bolderson E, Khanna KK, Burma S DNA Repair (Amst.) 2012 Apr 11 4 441-8
The dual PI3K/mTOR inhibitor NVP-BEZ235 is a potent inhibitor of ATM- and DNA-PKCs-mediated DNA damage responses.
Mukherjee B, Tomimatsu N, Amancherla K, Camacho CV, Pichamoorthy N, Burma S Neoplasia 2012 Jan 14 1 34-43
DNA double-strand breaks make bedfellows of ATM and AKT.
Mukherjee B, Burma S Cell Cycle 2011 Oct 10 19 3230
Targeting Non-Homologous End-Joining Through Epidermal Growth Factor Receptor Inhibition: Rationale and Strategies for Radiosensitization
B. Mukherjee, H. Choy, C. Nirodi, and S. Burma Seminars in Radiation Oncology October 2010 20 250-257
Loss of p15/Ink4b accompanies tumorigenesis triggered by complex DNA double-strand breaks
C. V. Camacho, B. Mukherjee, B. McEllin, L-H. Ding, B. Hu, A. Habib, X-J. Xie, C. Nirodi, D. Saha, M. Story, A. Balajee, R. M. Bachoo, D. A. Boothman, and S. Burma Carcinogenesis July 2010 31 1889-1896
PTEN Loss Compromises Homologous Recombination Repair in Astrocytes: Implications for Glioblastoma Therapy with Temozolomide or PARP Inhibitors
B. McElliin, C.V. Camacho, B. Mukherjee, B. Hahm, N. Tomimatsu, R.M. Bachoo, and S. Burma Cancer Research July 2010 70 5457-5464
Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks.
Bolderson E, Tomimatsu N, Richard DJ, Boucher D, Kumar R, Pandita TK, Burma S, Khanna KK Nucleic Acids Res. 2010 Apr 38 6 1821-31